The invention relates to an engineering vehicle active anti-rollover control system and method, belonging to the technical field of engineering vehicle security study. In the system of the invention, an input interface is connected with a rollover state detection module, an output interface is connected with a control module; an active hydro-pneumatic suspension fork controller, a differential braking system controller, a working device controller and a steering system controller are separately used to control an active hydro-pneumatic suspension fork, a differential braking system, a working device and a steering system; a voice warner and a pilot lamp warner receive the rollover hazard warning signals outputted by a anti-rollover central processing unit, and a vertical gyroscope is arranged in the cab of the engineering vehicle. By using the system of the invention, before the engineering vehicle rolls over, early warning signals can be provided for the driver and the rollover control system for rollover early warning, the height of the hydro-pneumatic suspension fork, the relative angle of the front and rear frames and the posture of the working equipment can be autonomously adjusted, and the braking force can be changed. Therefore, rollovers can be actively avoided so as to reduce rollover accidents fundamentally and realize the active protection of the rollover of engineering vehicles; and the system is easy to operate.