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发明公开
CN101747175A 药用级硬脂酸镁及其精制方法 有权

药用级硬脂酸镁及其精制方法
摘要：
本发明提供了一种药用级硬脂酸镁及其制备方法。该方法包括：(a)将食品级硬脂酸镁加入到溶解罐中，加入无水乙醇，在50-70℃的温度下以100-150rpm速度搅拌15-30分钟，其中硬脂酸镁和无水乙醇的混合比例为1∶10(g/ml)；(b)在获得的溶液中加入10-20g/L铁改性的海泡石吸附剂振荡吸附2-3h，过滤；(c)将滤液在60-70℃温度下减压蒸馏回收乙醇，收集产物；(d)将产物加入到溶解罐中，加入纯化水，在70-90℃的温度下以100-150rpm速度搅拌15-30分钟，其中硬脂酸镁和纯化水的混合比例为1∶8(g/ml)；(e)过滤，干燥，过筛，检验分装以得到产品。
摘要（英）：

The invention provides a medicinal-grade magnesium stearate and a refining process thereof. The process comprises the following steps: (a) adding a food-grade magnesium stearate in a dissolving tank and then adding absolute ethyl alcohol, stirring for 15 to 30 minutes at the speed of 100 to 150 rpm under the temperature of 50 to 70 DEG C, wherein the mixing proportion of the magnesium stearates and the absolute ethyl alcohol is 1 to 10 (g/ml); (b) adding 10 to 20 g/ml sepiolite absorbents modified by iron to the obtained solution for oscillation and absorption for 2 to 3 h and then filtering;(c) distilling the filtrate at reduced pressure under the temperature of 60 to 70 DEG C to recover ethyl alcohol, thereby collecting a product; (d) adding the product in the dissolving tank and adding purified water, stirring for 15 to 30 minutes at the speed of 100 to 150 rpm under the temperature of 70 to 90 DEG C, wherein the mixing proportion of the magnesium stearates and the purified water is 1 to 8 (g/ml); (e) filtering, drying, sieving, testing and split charging to obtain the product.

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