The invention provides compound health-care fruit wine prepared by adding a certain proportion of honey to the raw material of the apple and the pear. The method of preparing the apple-pear honey wine comprises the steps of mixing the apple juice, the pear juice and the honey, adding the yeast which is specially used for preparing the fruit wine, fermenting, filtering and ageing the mixture. The invention makes full use of the apple resource and the pear resource and solves the problems that it is difficult for the farmers to store and keep apples and pears fresh and sell the apples and the pears. The compound apple-pear honey wine has pure, soft and strong fruit flavor and bright color and has various health-care functions of building up the body, promoting the production of the body fluid, stimulating the appetite, moistening the lung, clearing away the heat, reducing the blood fat, eliminating the fatigue and defeating and preventing the cancer due to long-term drinking.