The invention relates to a biological modified producing peptide protein feed, which uses animal blood meal as a main raw material and uses beer grains as an auxiliary material, and is characterized in that the content of protein is 50-70 percent, the amino acid is equal or greater than 40 percent, and the true nutritive value of pepsin is equal or greater than 90 percent. The invention further comprises massive vitamin, minerals, probiotics and enzyme. The product of the invention is used for culture industries such as livestock and poultry, and has the functions of rapid proliferation and reducing feed conversion ratio and the like. The method for preparation is that using the process of combining mixed solid fermentation and adding exogenous compound enzyme, big molecular matters of the blood meal and the beer grains are biologically modified into small molecular protein, polypeptide and free amino acids and the like, and then being dried, crushed and packaged. The invention has the characteristics of simple process, easy operation, short production cycle, low production cost, and excellent product quality.