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公开(公告)号：US12025595B2
公开(公告)日：2024-07-02
申请号：US17281929
申请日：2019-10-04
Applicant: LECO Corporation
Inventor： Gaetano Stallone , Mark Firmer Merrick
CPC classification number: G01N30/30 , G01N2030/303 , G01N30/465 , G01N2030/623
Abstract: A thermal modulator for a chromatographic system includes a cooler, a thermal valve, a thermal buffer, a heater, and a capillary. The thermal valve thermally-engages the cooler. The thermal buffer thermally-engages the thermal valve. The heater thermally-engages the thermal buffer. The capillary thermally-engages the heater and is configured to transport an analyte in a first direction.
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公开(公告)号：US20240209517A1
公开(公告)日：2024-06-27
申请号：US18146485
申请日：2022-12-27
Applicant: DIONEX CORPORATION
Inventor： Yongjing Chen , Yan Liu
IPC: C25B1/02 , C25B1/22 , C25B11/042 , G01N30/62
CPC classification number: C25B1/02 , C25B1/22 , C25B11/042 , G01N30/62 , G01N2030/027
Abstract: An eluent generation module includes an electrolytic gas generator and an electrolytic eluent generator. The electrolytic gas generator includes a generation chamber having an inlet and an outlet; an outlet electrode within the generation chamber; a first ion exchange connector; a bulk solvent chamber separated from the generation chamber by the ion exchange connector; and a bulk solvent chamber electrode within the bulk solvent chamber. The electrolytic eluent generator includes an electrolyte chamber containing an aqueous electrolyte solution; an electrolyte chamber electrode within the electrolyte chamber; a second ion exchange connector; an eluent generation chamber separated from the electrolyte chamber by the second ion exchange connector; and an eluent generation chamber electrode.
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公开(公告)号：US20240201144A1
公开(公告)日：2024-06-20
申请号：US18555564
申请日：2022-02-21
Applicant: HITACHI HIGH TECH CORPORATION
Inventor： Daisuke Akieda , Yushi Harada , Mitsuhiko Uedo , Shoji Tomida , Yuichiro Hashimoto
CPC classification number: G01N30/32 , G01N30/14 , G01N30/62 , G01N30/86 , G01N30/8651 , G01N2030/027 , G01N2030/326
Abstract: A liquid chromatography (LC) that can supply a mobile phase to a storage bottle and can prevent mixing of air bubbles into a flow path without stopping analysis and liquid feeding. The LC includes a liquid feeding device that feeds out a mobile phase, a sample injection portion that injects a sample into the mobile phase, a column that separates the sample carried by the mobile, and a detection device that detects the sample. The LC further comprises a storage bottle that stores the mobile phase fed by the liquid feeding device, a mobile phase supply bottle that supplies the mobile phase to the storage bottle, a mobile phase supply pump that supplies the mobile phase to the storage bottle, and a control unit that controls an operation of the mobile phase supply pump and determines an amount of the mobile phase to be supplied to the storage bottle.
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公开(公告)号：US11879878B2
公开(公告)日：2024-01-23
申请号：US17422794
申请日：2019-08-06
Applicant: SHIMADZU CORPORATION
Inventor： Tasuku Murata , Mitsuru Nishishita , Shigeo Yasui
CPC classification number: G01N30/54 , B01D53/025 , G01N30/62 , B01D2253/106 , G01N2030/025
Abstract: A gas separation system includes a separation column for separating components contained in sample gas, a sample gas supplier fluidly connected to an inlet of the separation column for supplying sample gas to the separation column, a detector fluidly connected to an outlet of the separation column, a collection tube filled with an adsorbent having a property of adsorbing a target component in the sample gas under a condition of a first temperature or less and desorbing the adsorbed target component under a condition of a second temperature or more higher than the first temperature, a temperature adjuster for adjusting a temperature of the collection tube, a collection container for collecting the target component, and a switching mechanism for switching between a state in which the collection tube is connected to an outlet of the detector and a state in which the collection tube is connected to the collection container.
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公开(公告)号：US20230176017A1
公开(公告)日：2023-06-08
申请号：US17997018
申请日：2021-06-25
Applicant: CELANESE INTERNATIONAL CORPORATION
Inventor： Billy Charles TIPTON , Laiyuan CHEN , Yaw-Hwa LIU , Dheeraj KUMAR
Abstract: Ion chromatography may be used for measuring the concentration of metal ions in various streams of a vinyl acetate production process. For example, a method may comprise: reacting ethylene, oxygen, and acetic acid in the presence of a catalyst and optionally a catalyst promotor like sodium acetate and/or potassium acetate to yield a crude vinyl acetate stream; measuring a concentration of a metal ion of the crude vinyl acetate stream and/or a stream downstream thereof with an ion chromatograph, wherein the metal ion is selected from the group consisting of Group I metal ions, Group II metal ions, transition metal ions, and any combination thereof.
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公开(公告)号：US20230137952A1
公开(公告)日：2023-05-04
申请号：US18146491
申请日：2022-12-27
Applicant: DIONEX SOFTRON GMBH
Inventor： Martin Rendl
Abstract: A method for determining a state of a fluidic system can include measuring back pressures in the fluidic system at different times and determining a state of the fluidic system. The determination is based on at least the measured back pressures and on additional status information indicative of at least one status of the fluidic system at at least one of the different times.
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公开(公告)号：US20230034390A1
公开(公告)日：2023-02-02
申请号：US17786107
申请日：2020-12-15
Applicant: Seagen Inc.
Inventor： Jing Liu , Ethan Tyler Brickman , Luke David Munier Cody
Abstract: The present invention provides an analytical method for separating and optionally quantifying two or more buffers or excipients in a sample in a single assay.
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公开(公告)号：US20230003696A1
公开(公告)日：2023-01-05
申请号：US17930616
申请日：2022-09-08
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Daniel Intelmann , Julian Michely
IPC: G01N30/62
Abstract: A method for identifying and/or verifying at least one analyte peak in a chromatogram of a sample for said analyte from a liquid chromatography mass spectrometer device, said method comprising: a) determining a chromatogram of the sample by acquiring a plurality of data points for quantifier signal intensities and/or qualifier signal intensities, over time; and, in case the sample comprises an internal standard, optionally acquiring a plurality of data points for internal standard quantifier signal intensities and/or internal standard qualifier signal intensities, over time; b) determining for at least a fraction of the data points acquired in step a), a ratio type; c) comparing the ratios determined in step b) to a reference; and d) identifying and/or verifying at least one analyte peak in a chromatogram based on comparison step c).
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公开(公告)号：US11110385B2
公开(公告)日：2021-09-07
申请号：US16558228
申请日：2019-09-02
Applicant: PERKINELMER HEALTH SCIENCES, INC.
Inventor： Andrew Tipler
Abstract: A laminated microfluidic device is described that includes an internal microchannel formed from laminating individual layers of the laminated microfluidic device to each other. The laminated microfluidic device also includes a first port, a second port, a third port, and a fourth port each fluidically coupled to the internal microchannel. The laminated microfluidic device permits flow of sample into the laminated microfluidic device through the first port. The laminated microfluidic device fluidically couples to an external pressure source through the second port. The laminated microfluidic device permits the flow of the sample to a first component fluidically coupled to the third port and to a second component fluidically coupled to the fourth port depending on pressure within the internal microchannel of the laminated microfluidic device.
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公开(公告)号：US10948466B2
公开(公告)日：2021-03-16
申请号：US15449868
申请日：2017-03-03
Applicant: DIONEX CORPORATION
Inventor： Kannan Srinivasan , Mrinal Sengupta , SM Rahmat Ullah
Abstract: An in-line electrolytic reagent concentrator device that circumvents the need for additional pumps and supplies of reagents to support operation of a carbonate or ammonia removal device. The device generates regenerant solutions as strong as, or even stronger, than commercially recommended regenerant solutions. The device may also regenerate eluent solutions so as to reduce the frequency of eluent maintenance and replacement in ion chromatography systems.
