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公开(公告)号：US11471845B2
公开(公告)日：2022-10-18
申请号：US16441454
申请日：2019-06-14
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventor： Takenori Ikeda
IPC: B01J2/10 , H01M4/04 , H01M4/505 , H01M4/525 , H01M4/62 , H01M10/0585 , B01F29/64 , H01M10/0525 , H01M4/02
Abstract: A manufacturing method of a particle aggregate aggregated with wet particles in which active material particles and conductive particles are evenly dispersed and a manufacturing method of an electrode body including the particle aggregate are provided. The manufacturing method of a particle aggregate includes a first step of obtaining a first mixture by mixing conductive particles with a binder dispersion in which binder is dispersed in a dispersion medium, a second step of obtaining a clay-like mixture by kneading the first mixture with active material particles, and a third step of obtaining the particle aggregate aggregated with wet particles formed of the clay-like mixture.
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公开(公告)号：US20220298471A1
公开(公告)日：2022-09-22
申请号：US17698539
申请日：2022-03-18
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor： Eben Alsberg , Oju Jeon
Abstract: A method of forming a gel particle slurry includes providing a first solution that includes a cross-linkable hydrogel polymer macromer and an optional first crosslinker in a first depot and optionally a second solution in a second depot that is separated from the first depot by a mixing unit that includes a mixing element; and reversibly transferring the first solution and the optional second solution through the mixing unit between the first depot and the second depot such that the first solution and the optional second solution are mixed and agitated to form the gel particle slurry.
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公开(公告)号：US20220211713A1
公开(公告)日：2022-07-07
申请号：US17706783
申请日：2022-03-29
Applicant: Janssen Pharmaceutica NV
Inventor： Manish Kumar Gupta , Kaustubh Tambwekar , Binuraj Krishnan Nair , Dilip J. Gole , Maristella Bernini , Sabine Inghelbrecht
IPC: A61K31/519 , A61K9/48 , A61K9/00 , A61J3/07 , B01J2/22 , B01J2/10 , A61K47/02 , A61K47/12 , A61K9/10 , A61K47/38 , A23L33/10 , A23L33/16
Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate. In another embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, carboxymethylcellulose sodium, hydroxypropylmethylcellulose, citric acid monohydrate, disodium hydrogen phosphate, sucralose, sodium methyl parahydroxybenzoate, sodium ethyl parahydroxybenzoate, concentrated hydrochloric acid, sodium hydroxide, and water.
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公开(公告)号：US11014055B2
公开(公告)日：2021-05-25
申请号：US14004700
申请日：2012-03-13
Applicant: Stefan Gerl , Christina Klein
Inventor： Stefan Gerl , Christina Klein
Abstract: The present invention relates to a granulating and/or agglomerating tool for a granulating and/or agglomerating device with a fastening shaft and a substantially disk-shaped element with a diameter d which is fastened thereto and has an upper surface, a lower surface and a circumferential surface connecting the upper and the lower surface. In order to provide a granulating and/or agglomerating tool for a granulating and/or agglomerating device and a corresponding granulating and/or agglomerating device and a method for granulating or agglomerating with which the desired granulating or agglomerating result can be obtained very much faster and above all with a significantly finer granulated material with a significantly higher yield in the range of from 0.1 to 0.8 mm, it is proposed according to the invention that the circumferential surface exhibits a plurality of essentially V-shaped grooves running parallel to the axis of the shaft.
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公开(公告)号：US10526492B2
公开(公告)日：2020-01-07
申请号：US15608509
申请日：2017-05-30
Applicant: Saint-Gobain Ceramics & Plastics, Inc.
Inventor： Elodie Bahon , Pierre-Loup Judas , Nabil Nahas
IPC: C01B21/064 , C09C1/00 , C09C3/04 , C08K3/38 , B28B11/24 , C04B35/583 , C04B18/02 , C04B35/626 , C04B35/632 , C04B35/634 , C04B38/00 , B01J2/10
Abstract: Disclosed are methods for forming boron nitride-containing aggregates that exhibit improved wear by attrition, and resulting filled polymers that exhibit significantly improved thermal conductivity. The boron nitride-containing aggregates are prepared according to a method that includes wet granulating boron nitride powder with a granulation solution to form wet boron nitride-containing granules; and drying the wet boron nitride-containing granules to cause evaporation of solvent in the granulation solution, thereby forming boron nitride-containing granules. Sintering achieves the desired boron nitride-containing aggregates.
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公开(公告)号：US10207251B2
公开(公告)日：2019-02-19
申请号：US15392176
申请日：2016-12-28
Applicant: EURECAT S.A
Inventor： Pierre Dufresne , Pauline Galliou , Mathieu Baffert , Fabien Laboulfie
IPC: B01J2/10 , B01J2/12 , B01J2/16 , B01J20/26 , B01J20/08 , B01J20/28 , B01J20/32 , B01J21/04 , B01J23/882 , B01J31/06 , B01J31/34 , B01J35/00 , B01J37/02 , B01J2/00 , B01J23/85 , B01J33/00 , B01J23/94 , B01J23/883 , B01J23/888 , B01J35/02 , B01J35/10
Abstract: A process is disclosed for limiting the emissions of gases from a porous material in the form of particles comprising a porous inorganic support and at least 0.1% by weight of one or more compounds chosen from organic compounds, halogen compounds, boron compounds and phosphorus compounds. The particles are placed in motion within a hot gas stream traversing them, and a liquid composition containing one or more film-forming polymer(s) is sprayed over the moving particles by means of a twin-fluid atomization nozzle, in which the liquid composition is mixed with a pressurized gas, with a relative atomization pressure of greater than or equal to 0.7×1005 Pa, until a protective layer containing the film-forming polymer(s) and exhibiting a mean thickness of less than or equal to 20 μm is obtained on the surface of the said particles. A material resulting from this process is also disclosed.
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公开(公告)号：US10155996B2
公开(公告)日：2018-12-18
申请号：US15021301
申请日：2014-07-07
Applicant: PRIMETALS TECHNOLOGIES AUSTRIA GMBH
Inventor： Christoph Aichinger , Stefan Hoetzinger , Karl Laaber , Johann Reidetschlaeger
Abstract: A method and a device for producing granulates (1) which are obtained by the method steps: intensively mixing raw materials (2) and optionally additives (6) by adding water (3) to form a mixture (4); introducing the mixture (4) and optional additives (6) into a granulator (11); granulating the mixture (4) by adding water (3) to form raw granulates (12); introducing the raw granulates (12), water (3) and optional additives (6) into a rolling drum (17) and rolling the raw granulates (12) to form the granulates (1).
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公开(公告)号：US09950331B2
公开(公告)日：2018-04-24
申请号：US14785283
申请日：2014-04-24
Applicant: BASF Corporation
Inventor： Laura Beth Phillips , Brent Christopher Packer , David Chamberlain Roller , Richard Alan Moffitt, Jr. , Douglas Edward Grunder
CPC classification number: B05B12/006 , B01J2/006 , B01J2/10 , B05B1/14 , B05B7/12 , B05B12/12 , B05B15/25
Abstract: A method and apparatus are defined for coating a particulate material. The apparatus includes a mixer having a mixing chamber. A quantity of particulate material is fed into an inlet of the mixing chamber. An agitator is provided for mixing and conveying the particulate material. A feed system is also provided for delivery of a coating into the mixing chamber. The coating is delivered as an atomized spray directed at the mixing particulate material within the mixing chamber. A controller is provided for adjusting the flow of the coating into the mixing chamber based on the volumetric feed rate of the particulate material.
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公开(公告)号：US20170362440A1
公开(公告)日：2017-12-21
申请号：US15608509
申请日：2017-05-30
Applicant: Saint-Gobain Ceramics & Plastics, Inc.
Inventor： Elodie Bahon , Pierre-Loup Judas , Nabil Nahas
Abstract: Disclosed are methods for forming boron nitride-containing aggregates that exhibit improved wear by attrition, and resulting filled polymers that exhibit significantly improved thermal conductivity. The boron nitride-containing aggregates are prepared according to a method that includes wet granulating boron nitride powder with a granulation solution to form wet boron nitride-containing granules; and drying the wet boron nitride-containing granules to cause evaporation of solvent in the granulation solution, thereby forming boron nitride-containing granules. Sintering achieves the desired boron nitride-containing aggregates.
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公开(公告)号：US09440374B2
公开(公告)日：2016-09-13
申请号：US13990544
申请日：2011-03-03
Applicant: Raimund Schwarz , Stephan Poller , Markus Brunkau , Thomas Schill , Dick Van Dijk
Inventor： Raimund Schwarz , Stephan Poller , Markus Brunkau , Thomas Schill , Dick Van Dijk
CPC classification number: B29B9/08 , B01J2/10 , B29B9/14 , B29C47/0019 , B29C47/366 , B29C47/38 , B29C47/402 , B29C47/6031
Abstract: The invention relates to a device (1) for producing polymer agglomerates, comprising a compounder (2) having a housing (21) and a twin screw (22) arranged therein as well as a plurality of material inlets (3, 4) for admission of a polymer and additives, tempering units for heating the mix comprising polymer and additives, at least one degassing unit (5) and an outlet (23) and an agglomerating vessel (11) having an agglomerating tool (8) and a cooling tool (10). The agglomerating vessel (11) is connected via a connection channel (6) to the outlet (23) of the compounder (2), wherein the twin screw (22) of the compounder (2) is designed as a co-rotating twin Screw (22) and the agglomerating tool (8) of the agglomerating vessel (11) is arranged in the fall direction of the mix below the connection channel (6) and comprises mutually engaging rotors (81) and stators (82) for producing agglomerates of defined particle size. The invention further relates to a method for producing polymer agglomerates.
Abstract translation: 本发明涉及一种用于生产聚合物附聚物的装置（1），其包括具有壳体（21）和布置在其中的双螺杆（22）的混合器（2）以及用于进入的多个材料入口（3,4） 聚合物和添加剂的回火单元，用于加热包含聚合物和添加剂的混合物的回火单元，至少一个脱气单元（5）和出口（23）和具有附聚工具（8）和冷却工具（8）的附聚容器（11） 10）。 附聚容器（11）经由连接通道（6）连接到混合器（2）的出口（23），其中混合器（2）的双螺杆（22）被设计为同向旋转的双螺杆 （22）和附聚装置（11）的附聚工具（8）沿着连接通道（6）下方的混合物的倾倒方向布置，并且包括相互接合的转子（81）和定子（82），用于产生 定义的粒度。 本发明还涉及聚合物附聚物的制造方法。
