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    Method for Measuring Color Change of Oxidation-Reduction Indicator
    5.
    发明申请
    Method for Measuring Color Change of Oxidation-Reduction Indicator 有权
    测量氧化还原指示剂颜色变化的方法

    公开(公告)号：US20140322749A1

    公开(公告)日：2014-10-30

    申请号：US14348199

    申请日：2012-08-17

    Applicant: Eiji Nishinaga ,  Naho Suzuki ,  Takashi Hama ,  Isao Fukuta

    Inventor： Eiji Nishinaga ,  Naho Suzuki ,  Takashi Hama ,  Isao Fukuta

    IPC: C12Q1/14 ,  C12Q1/06

    CPC classification number: C12Q1/14 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/32 ,  G01N33/52 ,  G01N2333/9029

    Abstract: Provided is a method for measuring a color change of an oxidation-reduction indicator, which method is applicable to measurement of the cariogenic bacterial count and the like. A color change of an oxidation-reduction indicator is measured by a method for measuring a color change of an oxidation-reduction indicator, the method comprising reacting a test reagent with a test sample and measuring a color change, wherein the test reagent contains an oxidation-reduction indicator, an oxidation-reduction promoter, and a halogen salt.

    Abstract translation: 提供了一种用于测量氧化还原指示剂的颜色变化的方法，该方法可应用于致龋细菌计数的测量等。 通过测定氧化还原指示剂的颜色变化的方法测定氧化还原指示剂的颜色变化，所述方法包括使测试试剂与测试样品反应并测量颜色变化，其中测试试剂含有氧化 - 还原指示剂，氧化还原促进剂和卤素盐。

    ANALYTE SENSORS EMPLOYING MULTIPLE ENZYMES AND METHODS ASSOCIATED THEREWITH
    6.
    发明公开
    ANALYTE SENSORS EMPLOYING MULTIPLE ENZYMES AND METHODS ASSOCIATED THEREWITH 审中-公开

    公开(公告)号：US20240350047A1

    公开(公告)日：2024-10-24

    申请号：US18596447

    申请日：2024-03-05

    Applicant: Abbott Diabetes Care Inc.

    Inventor： Stephen OJA ,  Tianmei OUYANG ,  Hyun CHO ,  Benjamin J. FELDMAN ,  Namvar KIAIE

    IPC: A61B5/1486 ,  A61B5/145 ,  C12Q1/00

    CPC classification number: A61B5/14865 ,  A61B5/14532 ,  C12Q1/002 ,  C12Q1/005 ,  G01N2333/9029 ,  G01N2333/904 ,  G01N2333/908

    Abstract: Multiple enzymes may be present in the active area(s) of an electrochemical sensor to facilitate analysis of one or more analytes. The multiple enzymes may function independently to detect several analytes or in concert to detect a single analyte. One sensor configuration includes a first active area and a second active area, where the first active area has an oxidation-reduction potential that is sufficiently separated from the oxidation-reduction potential of the second active area to allow independent signal production. Some sensor configurations may have an active area overcoated with a multi-component membrane containing two or more different membrane polymers. Sensor configurations having multiple enzymes capable of interacting in concert include those in which a first enzyme converts an analyte into a first product and a second enzyme converts the first product into a second product, thereby generating a signal at a working electrode that is proportional to the analyte concentration.

    Analyte sensors employing multiple enzymes and methods associated therewith
    7.
    发明授权
    Analyte sensors employing multiple enzymes and methods associated therewith 有权

    公开(公告)号：US12048539B2

    公开(公告)日：2024-07-30

    申请号：US16774841

    申请日：2020-01-28

    Applicant: Abbott Diabetes Care Inc.

    Inventor： Stephen Oja ,  Tianmei Ouyang ,  Hyun Cho ,  Benjamin J. Feldman ,  Namvar Kiaie

    IPC: A61B5/1486 ,  A61B5/145 ,  C12Q1/00

    CPC classification number: A61B5/14865 ,  A61B5/14532 ,  C12Q1/002 ,  C12Q1/005 ,  G01N2333/9029 ,  G01N2333/904 ,  G01N2333/908

    Abstract: Multiple enzymes may be present in the active area(s) of an electrochemical sensor to facilitate analysis of one or more analytes. The multiple enzymes may function independently to detect several analytes or in concert to detect a single analyte. One sensor configuration includes a first active area and a second active area, where the first active area has an oxidation-reduction potential that is sufficiently separated from the oxidation-reduction potential of the second active area to allow independent signal production. Some sensor configurations may have an active area overcoated with a multi-component membrane containing two or more different membrane polymers. Sensor configurations having multiple enzymes capable of interacting in concert include those in which a first enzyme converts an analyte into a first product and a second enzyme converts the first product into a second product, thereby generating a signal at a working electrode that is proportional to the analyte concentration.

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