公开(公告)号：US10709140B2

公开(公告)日：2020-07-14

申请号：US15913109

申请日：2018-03-06

申请人： The University of The West Indies

发明人： Trevor Herbert Yee ,  Charah Tabetha Watson ,  Eric Garraway ,  Dwight Robinson ,  Nemoi Nastassia Sri Garcia Chisholm

IPC分类号： A01N65/36 ,  A01N65/00 ,  A01N65/08

摘要： The methods, kits, and products for controlling a target insect population are disclosed in which a non-host plant containing a toxin and a chemical attractant known to attract the target insect is treated with chemical attractant from a plant of interest. The chemical attractant induces the target insect to lay eggs on the non-host plant. The resulting offspring die of starvation from refusing to feed on the non-host plant. The non-host plant and plant of interest contain at least one common chemical. The methods, kits, and products for controlling a target insect population using an extract from a non-host plant are also disclosed. The non-host plant extract is applied to the plant of interest, and when ingested or applied directly to the target insect, kills the target insect or causes it to develop with deformities.

公开(公告)号：US08217187B2

公开(公告)日：2012-07-10

申请号：US12181412

申请日：2008-07-29

申请人： Trevor Herbert Yee ,  Helen Marjorie Jacobs

发明人： Trevor Herbert Yee ,  Helen Marjorie Jacobs

IPC分类号： C07D407/00

CPC分类号： C07D311/78

摘要： A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.

摘要翻译： 提供了使用美国食品和药物管理局一般被认可为安全的化合物从而提取和结晶类似物质的方法，例如来自含有这些化合物的天然来源的quassin和neoquassin。 特别地，提供了不需要使用乙酸铅，氯仿，甲醇或乙醚的提取方法。 该方法包括从提取的残余物中除去非极性和非极性物质的手段，以增强喹喔啉从残余物中的结晶。

公开(公告)号：US20230382926A1

公开(公告)日：2023-11-30

申请号：US18138452

申请日：2023-04-24

申请人： The University of The West Indies

发明人： Antonio RAMKISSOON ,  Adash RAMSUBHAG ,  Jayaraj JAYARAMAN

IPC分类号： C07D519/00 ,  A61P31/04 ,  A61K45/06

CPC分类号： C07D519/00 ,  A61P31/04 ,  A61K45/06

摘要： A compound of Formula I




or a pharmaceutically acceptable salt thereof is described. Compositions comprising the compound and methods of using the compound or composition to treat microbial infection are also described.

公开(公告)号：US08268369B2

公开(公告)日：2012-09-18

申请号：US13018679

申请日：2011-02-01

申请人： Curtis O. Green ,  Helen N. Asemota

发明人： Curtis O. Green ,  Helen N. Asemota

IPC分类号： A61K36/752

CPC分类号： A61K31/352

摘要： The invention relates to compositions and methods for treating hypercholesterolemia, including methods for increasing HDL cholesterol levels, using a composition comprising an extract from the Ortanique peel. The invention also relates to compositions and methods for treating hypercholesterolemia, including methods for increasing HDL cholesterol levels, using a composition comprising substantially similar amounts of tetramethylscutellarein and nobiletin by weight and/or a composition comprising substantially similar amounts of tetramethylscutellarein, nobiletin, and tangeretin by weight.

摘要翻译： 本发明涉及使用包含Ortanique皮的提取物的组合物治疗高胆固醇血症的组合物和方法，包括增加HDL胆固醇水平的方法。 本发明还涉及用于治疗高胆固醇血症的组合物和方法，包括用于增加HDL胆固醇水平的方法，使用包含基本上相似量的四甲基透明质酸和新柏林重量的组合物和/或包含基本上相似量的四甲基盾草甙，诺贝利和蒂内宾的组合物， 重量。

公开(公告)号：US08778689B1

公开(公告)日：2014-07-15

申请号：US12126639

申请日：2008-05-23

申请人： Gurdial Singh ,  Patrice G. J. Plaza ,  Bhoomendra A. Bhongade

发明人： Gurdial Singh ,  Patrice G. J. Plaza ,  Bhoomendra A. Bhongade

IPC分类号： C07H19/052 ,  C07H1/06 ,  G01N21/31 ,  G01N21/33 ,  G01N21/35 ,  G01N24/08

CPC分类号： C07H19/052 ,  C07H1/06 ,  G01N21/31

摘要： We disclose the synthesis and use of chiral ionic liquids based on a substituted pentose, furanose, hexose, or pyranose sugar. The compounds and processes to make or use them are provided.

摘要翻译： 我们公开了基于取代的戊糖，呋喃糖，己糖或吡喃糖的手性离子液体的合成和使用。 提供了制备或使用它们的化合物和方法。

公开(公告)号：US08129102B2

公开(公告)日：2012-03-06

申请号：US12485512

申请日：2009-06-16

申请人： Paul S. Ramphal

发明人： Paul S. Ramphal

IPC分类号： G09B23/28 ,  A01N1/00

CPC分类号： G09B23/30 ,  G09B23/288

摘要： A method is described and disclosed for harvesting and preparing porcine hearts that may be used, among other things, as an improved analog of the human heart in cardiac simulator systems for training surgical personnel for performing beating heart surgery.

摘要翻译： 描述和公开了用于收获和制备猪心脏的方法，其可以用于心脏模拟器系统中用于训练外科人员进行搏动心脏手术的心脏的改进的类似物。

公开(公告)号：US07404972B2

公开(公告)日：2008-07-29

申请号：US11450423

申请日：2006-06-12

申请人： Trevor Herbert Yee ,  Helen Marjorie Jacobs

发明人： Trevor Herbert Yee ,  Helen Marjorie Jacobs

IPC分类号： A61K36/00

CPC分类号： C07D311/78

摘要： A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.

摘要翻译： 提供了使用美国食品和药物管理局一般被认可为安全的化合物从而提取和结晶类似物质的方法，例如来自含有这些化合物的天然来源的quassin和neoquassin。 特别地，提供了不需要使用乙酸铅，氯仿，甲醇或乙醚的提取方法。 该方法包括从提取的残余物中除去非极性和非极性物质的手段，以增强喹喔啉从残余物中的结晶。

公开(公告)号：US08710247B2

公开(公告)日：2014-04-29

申请号：US13545720

申请日：2012-07-10

申请人： Trevor Herbert Yee ,  Helen Marjorie Jacobs

发明人： Trevor Herbert Yee ,  Helen Marjorie Jacobs

IPC分类号： C07D311/78

CPC分类号： C07D311/78

摘要： A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.

摘要翻译： 提供了使用美国食品和药物管理局一般被认可为安全的化合物从而提取和结晶类似物质的方法，例如来自含有这些化合物的天然来源的quassin和neoquassin。 特别地，提供了不需要使用乙酸铅，氯仿，甲醇或乙醚的提取方法。 该方法包括从提取的残余物中除去非极性和非极性物质的手段，以增强喹喔啉从残余物中的结晶。

公开(公告)号：US20140100279A1

公开(公告)日：2014-04-10

申请号：US14046759

申请日：2013-10-04

申请人： THE UNIVERSITY OF THE WEST INDIES

发明人： Denise DALEY-BECKFORD ,  Trevor Herbert YEE ,  Ruby Lisa ALEXANDER-LINDO ,  Paul Bancroft REESE

IPC分类号： A61K31/201 ,  A61K31/01 ,  A61K31/20

CPC分类号： A61K31/201 ,  A61K31/01 ,  A61K31/20 ,  A61K36/61 ,  A61K2300/00

摘要： The present invention relates to the discovery that compounds isolated from the leaves of the plant Eucalyptus camaldulensis can be used to treat or prevent hyperglycemia and/or hypertension.

摘要翻译： 本发明涉及从植物桉树叶中分离的化合物可用于治疗或预防高血糖和/或高血压的发现。

公开(公告)号：US08445042B2

公开(公告)日：2013-05-21

申请号：US12403760

申请日：2009-03-13

申请人： Michelle A. Hamilton Hamilton ,  Garth S. Dawkins ,  Winston A. Mellowes

发明人： Michelle A. Hamilton Hamilton ,  Garth S. Dawkins ,  Winston A. Mellowes

IPC分类号： A23L1/08

CPC分类号： C12N1/20 ,  A23L29/27 ,  C12P19/06

摘要： Disclosed herein is a method of making xanthan gum by inoculating sugarcane fluid with a bacterium that can synthesize xanthan gum, such as a bacterium of the genus Xanthomonas.

摘要翻译： 本文公开了通过用可合成黄原胶的细菌（例如黄单胞菌属的细菌）接种甘蔗液制备黄原胶的方法。