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1.发明授权Benzimidazole derivatives and their use for modulating the GABAA receptor complex 有权苯并咪唑衍生物及其用于调节GABA A受体复合物的用途公开(公告)号：US08492408B2
公开(公告)日：2013-07-23
申请号：US13129066
申请日：2009-11-13
Applicant: Janus S. Larsen , Philip K. Ahring , Elsebet Østergaard Nielsen , Naheed Mirza
Inventor： Janus S. Larsen , Philip K. Ahring , Elsebet Østergaard Nielsen , Naheed Mirza
IPC: A61K31/4439 , C07D401/14
CPC classification number: C07D401/14
Abstract: The present application discloses novel benzimidazole derivatives and their use as modulators of the GABAA receptor complex. In other aspects the application discloses the use of these compounds, in a method for therapy and to pharmaceutical compositions comprising these compounds.
Abstract translation: 本申请公开了新的苯并咪唑衍生物及其作为GABA A受体复合物调节剂的用途。 在其它方面，本申请公开了这些化合物在治疗方法中的用途以及包含这些化合物的药物组合物。
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Patent Agency Ranking
2.发明授权Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors 有权色烯-2-酮衍生物及其作为单胺神经递质再摄取抑制剂的用途公开(公告)号：US09133184B2
公开(公告)日：2015-09-15
申请号：US14263664
申请日：2014-04-28
Applicant: ANIONA APS
Inventor： Dan Peters , Gordon Munro , Elsebet Ostergaard Nielsen , Karin Sandager Nielsen
IPC: A01N43/42 , A61K31/44 , C07D451/06
CPC classification number: C07D451/06
Abstract: The present application discloses novel 8-aza-bicyclo[3.2.1]oct-3-yloxy)-chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the application discloses the use of these compounds, a method for therapy and to pharmaceutical compositions comprising these compounds.
Abstract translation: 本申请公开了可用作单胺神经递质再摄取抑制剂的新颖的8-氮杂 - 双环[3.2.1]辛-3-基氧基） - 色烯-2-酮衍生物。 在其它方面，本申请公开了这些化合物的使用，治疗方法和包含这些化合物的药物组合物。
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3.发明申请CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS 有权CHROMEN-2-ONE衍生物及其作为单胺神经递质抑制剂的用途公开(公告)号：US20140235669A1
公开(公告)日：2014-08-21
申请号：US14263664
申请日：2014-04-28
Applicant: ANIONA APS
Inventor： Dan PETERS , Gordon MUNRO , Elsebet Ostergaard NIELSEN , Karin Sandager NIELSEN
IPC: C07D451/06
CPC classification number: C07D451/06
Abstract: The present application discloses novel 8-aza-bicyclo[3.2.1]oct-3-yloxy)-chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the application discloses the use of these compounds, a method for therapy and to pharmaceutical compositions comprising these compounds.
Abstract translation: 本申请公开了可用作单胺神经递质再摄取抑制剂的新颖的8-氮杂 - 双环[3.2.1]辛-3-基氧基） - 色烯-2-酮衍生物。 在其它方面，本申请公开了这些化合物的使用，治疗方法和包含这些化合物的药物组合物。
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4.发明授权Carbonylamino derivatives useful for the treatment of certain inflammatory disorders 有权用于治疗某些炎性疾病的羰基氨基衍生物公开(公告)号：US08455549B2
公开(公告)日：2013-06-04
申请号：US12674746
申请日：2008-08-21
Applicant: Lars Siim Madsen , Palle Christophersen
Inventor： Lars Siim Madsen , Palle Christophersen
IPC: A61K31/165 , A61P1/04
CPC classification number: A61K31/165
Abstract: The present invention relates to the use of a particular group of carbonylamino derivatives for the treatment or alleviation of a disease or condition relating to certain inflammatory disorders.
Abstract translation: 本发明涉及特定的一组羰基氨基衍生物用于治疗或减轻与某些炎性疾病有关的疾病或病症的用途。
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5.发明授权Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors 有权色烯-2-酮衍生物及其作为单胺神经递质再摄取抑制剂的用途公开(公告)号：US08697721B2
公开(公告)日：2014-04-15
申请号：US13319955
申请日：2010-05-06
Applicant: Dan Peters , Elsebet Østergaard Nielsen , Karin Sandager Nielsen , Gordon Munro
Inventor： Dan Peters , Elsebet Østergaard Nielsen , Karin Sandager Nielsen , Gordon Munro
IPC: A01N43/42 , A61K31/44 , C07D401/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00 , C07D421/00
CPC classification number: C07D451/06 , A61K31/46
Abstract: The present applications discloses novel 8-aza-bicyclo[3.2.1]oct-3-yloxy)-chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors. In other aspects the applications discloses the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
Abstract translation: 本申请公开了新颖的8-氮杂 - 双环[3.2.1]辛-3-基氧基） - 苯并二氢吡喃-2-酮衍生物及其作为单胺神经递质再摄取抑制剂的用途。 在其它方面，申请公开了这些化合物在治疗方法中的用途以及包含本发明化合物的药物组合物。
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![8-azabicyclo[3.2.1]oct-2-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors](/abs-image/US/2014/01/21/US08633218B2/abs.jpg.150x150.jpg)
6.发明授权8-azabicyclo[3.2.1]oct-2-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors 有权8-氮杂双环[3.2.1]辛-2-烯衍生物及其作为单胺神经递质再摄取抑制剂的用途公开(公告)号：US08633218B2
公开(公告)日：2014-01-21
申请号：US13129561
申请日：2009-11-16
Applicant: Dan Peters , David Spencer Jones , Elsebet Østergaard Nielsen
Inventor： Dan Peters , David Spencer Jones , Elsebet Østergaard Nielsen
CPC classification number: C07D409/04
Abstract: The present invention relates to novel 8-azabicyclo[3.2.1]oct-2-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
Abstract translation: 本发明涉及可用作单胺神经递质再摄取抑制剂的新型8-氮杂双环[3.2.1]辛-2-烯衍生物。 在其它方面，本发明涉及这些化合物在治疗方法中的用途以及包含本发明化合物的药物组合物。
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