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公开(公告)号：US20160251633A1
公开(公告)日：2016-09-01
申请号：US15155445
申请日：2016-05-16
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventor： Masayoshi MURAMATSU , Masakazu ITO
CPC classification number: C12N9/0006 , C12N9/1205 , C12N9/13 , C12N9/88 , C12N9/90 , C12N15/52 , C12N15/81 , C12P7/02 , C12P7/04 , C12P7/54 , C12P7/62 , C12P19/32 , C12Y101/01001 , C12Y207/01011 , C12Y208/03008 , C12Y401/01004 , C12Y401/02009 , Y02P20/52
Abstract: Substance productivity is improved by introducing a metabolic pathway for synthesis of acetyl-CoA or acetic acid from glucose-6-phosphate into yeast. Acetic acid productivity, acetyl-CoA productivity, and productivity of a substance made from acetyl-CoA-derived are improved by attenuating genes involved in the glycolytic system of yeast and introducing a phosphoketolase gene into the yeast.
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公开(公告)号：US20240310343A1
公开(公告)日：2024-09-19
申请号：US18271532
申请日：2022-01-14
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA , INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION RESEARCH ORGANIZATION OF INFORMATION AND SYSTEMS
Inventor： Akinobu TOYODA , Masakazu ITO , Satoshi KATAHIRA , Yuji MATSUO , Akinori IKEUCHI , Ken KUROKAWA , Koichi HIGASHI , Hiroshi MORI
IPC: G01N33/00
CPC classification number: G01N33/0027
Abstract: Provided is a novel space evaluation system capable of simply and quantitatively evaluating how close an unknown space is to a natural environment. The space evaluation system 1 comprises: a setting unit 12 for setting naturalness as an index of how close a space is to a natural environment; and an estimating unit 11 for estimating, from air quality data indicating a type of material including a microbe included in a sample collected from air in a target space to be evaluated and indicating an abundance of each material, the naturalness of the target space from which the sample has been collected.
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公开(公告)号：US20170233713A1
公开(公告)日：2017-08-17
申请号：US15497685
申请日：2017-04-26
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventor： Masayoshi MURAMATSU , Masakazu ITO
IPC: C12N9/00
CPC classification number: C12N9/93 , C12N9/0008 , C12P5/02 , C12Y102/01048 , C12Y601/00
Abstract: A hydrocarbon synthase gene encoding protein having excellent capacity to synthesize a hydrocarbon such as alkane and novel functions is provided. The gene encodes a protein comprising an amino acid sequence comprising a motif sequence shown in SEQ ID NO: 1 and having activity of synthesizing a hydrocarbon with a carbon number one less than that of an aldehyde compound from the aldehyde compound.
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4.发明申请
公开(公告)号：US20150344913A1
公开(公告)日：2015-12-03
申请号：US14717019
申请日：2015-05-20
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA , KYOTO UNIVERSITY
Inventor： Chikara OHTO , Masayoshi MURAMATSU , Masakazu ITO , Jun OGAWA , Shigenobu KISHINO
IPC: C12P5/02
CPC classification number: C12P5/02 , C12P7/04 , C12Y102/0105
Abstract: This invention provides a recombinant microorganism into which an acyl-CoA reductase exerting excellent activity in a reduction reaction involving the use of acyl-CoA as a substrate has been introduced. Such recombinant microorganism comprises a nucleic acid encoding a protein (a) or (b) below introduced into a host microorganism: (a) a protein comprising the amino acid sequence of SEQ ID NO: 2; or (b) a protein comprising an amino acid sequence having 70% or higher identity to the amino acid sequence of SEQ ID NO: 2 and having activity for synthesizing an aldehyde compound from acyl-CoA.
Abstract translation: 本发明提供了一种重组微生物，其中引入了在涉及使用酰基辅酶A作为底物的还原反应中具有优异活性的酰基辅酶A还原酶。 这样的重组微生物包含编码下文中引入到宿主微生物中的蛋白质（a）或（b））的核酸：（a）包含SEQ ID NO：2的氨基酸序列的蛋白质; 或（b）包含与SEQ ID NO：2的氨基酸序列具有70％或更高同一性的氨基酸序列并具有从酰基辅酶A合成醛化合物的活性的蛋白质。
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5.发明申请RECOMBINANT MICROORGANISM AND METHOD FOR PRODUCING A SUBSTANCE USING THE SAME 审中-公开重组微生物和使用该物质生产物质的方法
公开(公告)号：US20150344851A1
公开(公告)日：2015-12-03
申请号：US14716973
申请日：2015-05-20
Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA , KYOTO UNIVERSITY
Inventor： Chikara OHTO , Masayoshi MURAMATSU , Masakazu ITO , Jun OGAWA , Shigenobu KISHINO
CPC classification number: C12N9/0008 , C12P5/00 , C12P7/04 , C12P7/24 , C12Y102/0105
Abstract: This invention provides a recombinant microorganism into which an acyl-CoA reductase exhibiting excellent activity in a reduction reaction using acyl-CoA as a substrate has been introduced. Such recombinant microorganism comprises a nucleic acid encoding an acyl-CoA reductase comprising any of characteristic Common sequences 1 to 3 introduced into a host microorganism.
Abstract translation: 本发明提供一种重组微生物，其中引入了使用酰基辅酶A作为底物的还原反应中表现出优异活性的酰基辅酶A还原酶。 这种重组微生物包含编码引入宿主微生物中的任何特征性通用序列1-3的酰基辅酶A还原酶的核酸。
