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公开(公告)号：US10052590B2
公开(公告)日：2018-08-21
申请号：US14900051
申请日：2014-06-20
Applicant: TORAY INDUSTRIES, INC.
Inventor： Aya Nishio , Norihiro Takeuchi , Atsushi Kobayashi
IPC: B01D21/24 , B01D61/58 , B01D61/22 , B01D65/02 , B01D61/14 , B01D61/18 , B01D63/02 , B01D63/04 , B01D61/08 , C12M1/00
CPC classification number: B01D61/58 , B01D61/08 , B01D61/147 , B01D61/18 , B01D61/22 , B01D63/02 , B01D63/04 , B01D65/02 , B01D2311/14 , B01D2311/16 , B01D2315/10 , B01D2315/12 , B01D2317/022 , B01D2317/04 , B01D2321/04 , B01D2321/16 , C12M29/04
Abstract: In order to efficiently transport a filtration target liquid to a separation membrane module and to facilitate additional simplification of equipment in a filtration device including the separation membrane modules in which a plurality of lines thereof are disposed in series, a filtration device according to the present invention is a filtration device including a plurality of separation membrane modules each of which separates a liquid to be filtrated into a permeated liquid and a non-permeated liquid, in which the filtration device includes: a series non-permeated liquid flow channel that forms a series unit by connecting non-permeation sides of the plurality of separation membrane modules in series; and a parallel permeated liquid flow channel that forms a parallel unit by connecting permeation sides of the plurality of separation membrane modules in parallel.
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2.发明申请公开(公告)号：US20170291145A1
公开(公告)日：2017-10-12
申请号：US15507522
申请日：2015-09-01
Applicant: TORAY INDUSTRIES, INC.
Inventor： Shun Shimura , Atsushi Kobayashi , Norihiro Takeuchi , Yoshiki Okamoto
CPC classification number: B01D63/04 , B01D65/022 , B01D69/08 , B01D2313/44 , B01D2321/00
Abstract: A hollow-fiber membrane module of the invention includes: a cylindrical case having a first end and a second end in a height direction thereof; a hollow-fiber membrane bundle being housed in the cylindrical case and having a plurality of hollow-fiber membranes each closed at an end part on the first end side and opened at an end part on the second end side; a first binding part binding the end parts on the first end side of the hollow-fiber membranes; a first flow channel guiding fluid to pass through the first binding part from the first end side to the second end side of the first binding part; and a channel material directing, at a terminal on the second end side of the first flow channel, a flow of at least a part of the fluid flowing out from the terminal on the second end side of the first flow channel toward a direction intersecting the height direction of the cylindrical case.
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3.发明申请公开(公告)号：US20150050694A1
公开(公告)日：2015-02-19
申请号：US14385627
申请日：2013-03-01
Applicant: TORAY INDUSTRIES, INC.
Inventor： Norihiro Takeuchi , Atsushi Kobayashi
CPC classification number: C12M37/02 , A61L2/07 , A61L2202/17 , B01D65/022 , B01D67/0093 , B01D69/08 , B01D69/12 , B01D71/34 , B01D2321/08 , C12M33/14 , C12M37/00 , C12P7/56
Abstract: A method of sterilizing a separation membrane module using water vapor includes: a liquid supplying step of supplying a liquid having a boiling point of 80° C. or higher at atmospheric pressure to a secondary side of the separation membrane module such that a filling ratio of the liquid in a space surrounded by a filtration portion of a separation membrane is 70% or more, the filtration portion being used for filtration; a liquid sealing step of isolating the secondary side of the separation membrane module such that the filling ratio of the liquid supplied to the secondary side in the liquid supplying step is 70% or more; and a sterilization step of sterilizing the separation membrane module by supplying water vapor to a primary side of the separation membrane module while the secondary side of the separation membrane module is isolated.
Abstract translation: 使用水蒸气对分离膜组件进行灭菌的方法包括：向大气压下的沸点为80℃以上的液体供给到分离膜组件的二次侧的液体供给工序， 由分离膜的过滤部包围的空间中的液体为70％以上，过滤部用于过滤; 液体密封步骤，分离所述分离膜组件的二次侧，使得在所述液体供给步骤中供给到所述次级侧的液体的填充率为70％以上; 以及灭菌步骤，在分离膜组件的二次侧分离时，通过向分离膜组件的初级侧供给水蒸气来对分离膜组件进行灭菌。
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公开(公告)号：US10207226B2
公开(公告)日：2019-02-19
申请号：US14911503
申请日：2014-09-26
Applicant: TORAY INDUSTRIES, INC.
Inventor： Atsushi Kobayashi , Shun Shimura , Mikiko Ikeda , Norihiro Takeuchi , Shinya Takeuchi
Abstract: A cartridge type hollow fiber membrane module including a housing, a hollow-fiber membrane bundle having a plurality of hollow fiber membranes, a first potting part that bonds the hollow fiber membranes at at least one end of the bundle of the plurality of hollow fiber membranes such that the hollow fiber membranes are open, and a sealing material that fixes the first potting part to the housing liquid-tightly, wherein the first potting part comprises an inner potting part and an outer potting part, wherein the inner potting part and the outer potting part are both formed of a potting material, wherein the sealing material is in contact with the outer potting part, and wherein both the inner potting part and the outer potting part are formed in a sealing direction of the sealing material.The cartridge type hollow fiber membrane module is free of leakage and contamination due to separation of a potting material even when steam sterilization is performed.
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公开(公告)号：US20190262774A1
公开(公告)日：2019-08-29
申请号：US16407763
申请日：2019-05-09
Applicant: Toray Industries, Inc.
Inventor： Hiroshi Matsumoto , Mikiko Ikeda , Atsushi Kobayashi , Shun Shimura , Norihiro Takeuchi , Hiroaki Kanai
Abstract: A housing (30) of a hollow-fiber membrane module (101) is so configured as to have a small-diameter part (3B) having an inner diameter smaller than an inner diameter of a flow regulation cylinder (9) facing a part of the housing (30) on which a nozzle (8) is provided, and which is arranged on a lower side than a lower end of the flow regulation cylinder (9) in an axial direction of the hollow-fiber membrane module (101); or the flow regulation cylinder (9) is so configured as to have a small-diameter part (9G) which has an inner diameter smaller than the inner diameter of the flow regulation cylinder (9) facing the part of the housing (30) on which the nozzle (8) is provided, and which is arranged on a lower side than the existing region of the flow regulation holes (10) in the axial direction of the hollow-fiber membrane module (101).
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Patent Agency Ranking
公开(公告)号：US10350549B2
公开(公告)日：2019-07-16
申请号：US15507522
申请日：2015-09-01
Applicant: TORAY INDUSTRIES, INC.
Inventor： Shun Shimura , Atsushi Kobayashi , Norihiro Takeuchi , Yoshiki Okamoto
Abstract: A hollow-fiber membrane module of the invention includes: a cylindrical case having a first end and a second end in a height direction thereof; a hollow-fiber membrane bundle being housed in the cylindrical case and having a plurality of hollow-fiber membranes each closed at an end part on the first end side and opened at an end part on the second end side; a first binding part binding the end parts on the first end side of the hollow-fiber membranes; a first flow channel guiding fluid to pass through the first binding part from the first end side to the second end side of the first binding part; and a channel material directing, at a terminal on the second end side of the first flow channel, a flow of at least a part of the fluid flowing out from the terminal on the second end side of the first flow channel toward a direction intersecting the height direction of the cylindrical case.
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公开(公告)号：US09795923B2
公开(公告)日：2017-10-24
申请号：US14384994
申请日：2013-02-14
Applicant: TORAY INDUSTRIES, INC.
Inventor： Hayato Inuzuka , Kohei Fujii , Norihiro Takeuchi , Atsushi Kobayashi , Takashi Mimitsuka
CPC classification number: B01D63/02 , B01D63/04 , B01D2313/02 , B01D2313/21 , B01D2313/44 , B01D2317/04
Abstract: A cartridge type hollow fiber membrane module includes: a cartridge type hollow fiber membrane element including a hollow fiber membrane bundle, a distribution cylinder, and an adhesive resin portion; a module case including a module case main body portion which has at least one port corresponding to a supply outlet of filtrate or an undiluted solution on a side surface, and a header which has a port corresponding to a supply outlet of filtrate or an undiluted solution, and accommodating the cartridge type hollow fiber membrane element; a first sealing member disposed to come into contact with the distribution cylinder and the header on an external side of a boundary surface between the supporting portion and the adhesive resin portion; and a second sealing member disposed to come into contact with an outer circumference portion of the distribution cylinder and the module case main body portion.
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8.发明申请METHOD OF PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION AND CONTINUOUS FERMENTATION APPARATUS 有权通过连续发酵和连续发酵装置生产化学品的方法公开(公告)号：US20150056665A1
公开(公告)日：2015-02-26
申请号：US14388306
申请日：2013-03-27
Applicant: Toray Industries, Inc.
Inventor： Satoko Kanamori , Hideki Sawai , Norihiro Takeuchi
IPC: C12P13/24 , C12P13/14 , C12P13/22 , C12P13/12 , C12P13/00 , C12P13/10 , C12P13/20 , C12P13/06 , C12P13/08 , C12P7/56
CPC classification number: C12P13/24 , C12M29/04 , C12M33/14 , C12M41/34 , C12P7/56 , C12P13/001 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227
Abstract: A method of producing a chemical includes culturing cells in a culture solution in a fermentor to ferment a feedstock to produce a chemical; supplying the culture solution containing the chemical produced in the culturing to a plurality of separation membrane units arranged in parallel; filtering the culture solution supplied in the supplying to separate a permeate containing the chemical; refluxing a retentate that is not filtered in the filtering to the fermentor; and supplying a gas containing oxygen to the plurality of separation membrane units while a supply amount is changed to at least two different values to perform scrubbing, wherein the supply amount and supply time of the gas containing oxygen supplied in the culturing and the supplying the gas are set so that a kLa value is within a predetermined range from an optimal kLa value for the cells cultured in the culturing.
Abstract translation: 生产化学品的方法包括在发酵罐的培养液中培养细胞以发酵原料以生产化学品; 将含有培养中生成的化学品的培养液供给到并列配置的多个分离膜单元; 过滤供应中提供的培养液以分离含有化学品的渗透物; 在过滤中回流未过滤的保留物到发酵罐; 向多个分离膜单元供给含氧气体，同时将供给量变更为至少两个不同的值进行洗涤，其中，在培养中供给的气体和供给气体的供给量和供给时间 被设定为使得kLa值在培养中培养的细胞的最佳kLa值的预定范围内。
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公开(公告)号：US09895664B2
公开(公告)日：2018-02-20
申请号：US14786932
申请日：2014-04-24
Applicant: TORAY INDUSTRIES, INC.
Inventor： Atsushi Kobayashi , Hayato Inuzuka , Shun Shimura , Norihiro Takeuchi
CPC classification number: B01D63/04 , B01D63/02 , B01D2313/02 , B01D2313/04 , B01D2313/08 , B01D2315/08 , C02F1/44
Abstract: A cartridge type hollow-fiber membrane module of the present invention includes: a housing; a plurality of hollow fiber membranes housed in the housing; a first potting part which bundles first ends of the hollow fiber membranes while keeping the first ends open; a second potting part which bundles second ends of the hollow fiber membranes while keeping the second ends sealed; a fixing part which detachably fixes the first potting part to the housing; a sealing part which liquid-tightly seals a space between the first potting part and the housing; and a holding part which holds the second potting part so that the second potting part is detachable from the housing and so that liquids can pass through a space between the second potting part and the housing.
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10.发明授权公开(公告)号：US09644221B2
公开(公告)日：2017-05-09
申请号：US14388306
申请日：2013-03-27
Applicant: Toray Industries, Inc.
Inventor： Satoko Kanamori , Hideki Sawai , Norihiro Takeuchi
IPC: C12P1/00 , C12P13/24 , C12P7/56 , C12P13/04 , C12M1/00 , C12M1/26 , C12M1/34 , C12P13/00 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/22
CPC classification number: C12P13/24 , C12M29/04 , C12M33/14 , C12M41/34 , C12P7/56 , C12P13/001 , C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/222 , C12P13/225 , C12P13/227
Abstract: A method of producing a chemical includes culturing cells in a culture solution in a fermentor to ferment a feedstock to produce a chemical; supplying the culture solution containing the chemical produced in the culturing to a plurality of separation membrane units arranged in parallel; filtering the culture solution supplied in the supplying to separate a permeate containing the chemical; refluxing a retentate that is not filtered in the filtering to the fermentor; and supplying a gas containing oxygen to the plurality of separation membrane units while a supply amount is changed to at least two different values to perform scrubbing, wherein the supply amount and supply time of the gas containing oxygen supplied in the culturing and the supplying the gas are set so that a kLa value is within a predetermined range from an optimal kLa value for the cells cultured in the culturing.
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