-
1.发明申请公开(公告)号：US20250044304A1
公开(公告)日：2025-02-06
申请号：US18784874
申请日：2024-07-25
Inventor： Karina R. Seferian , Evgenia O. Kuzichkina , Erzhena G. Altaeva , Fedor N. Rozov , Stanislav V. Kozlovsky , Yury N. Lezhnin , Kristina M. Gaynova , Liudmila V. Ageeva , Natalia A. Gruzdeva , Natalia N. Tamm , Elizaveta D. Kulieva , Anna A. Trufanova , Sergei A. Kotlov , Chengxiong ZHAN , Qixue SONG , Tao TANG , Yufeng YAN , Ke LI
Abstract: The present application relates to an antibody, kit, detection method, and sample analyzer for detecting thyroid stimulating hormone. Specifically, the present application relates to a monoclonal antibody or antigen-binding antibody fragment thereof that specifically binds to thyroid stimulating hormone (TSH), wherein the antibody can recognize TSH variant R55G and does not cross-react with an α-subunit shared by human luteinizing hormone (LH), follicle stimulating hormone (FSH), human chorionic gonadotropin (hCG), and free glycoprotein hormones, and is particularly suitable for developing TSH detection kit with a functional sensitivity of ≤0.0015 μIU/ml. The present application also relates to a thyroid stimulating hormone detection kit, detection method, and sample analyzer.
-
公开(公告)号：US20240360205A1
公开(公告)日：2024-10-31
申请号：US18648572
申请日：2024-04-29
Inventor： Vladimir L. Filatov , Petr N. Datskevich , Antonina S. Kokisheva , Alexey G. Katrukha , Stanislav V. Kozlovsky , Alexander B. Postnikov , Fedor N. Rozov , Tao TANG , Chengxiong ZHAN , Lingjia WU , Shibo ZHU , Ke LI , Yue WU
CPC classification number: C07K16/18 , G01N33/6854 , C07K2317/565
Abstract: The present application relates to a PINP-specific antibody, kit and use thereof. Specifically, the present invention provides a PINP-specific antibody, as well as a kit containing the antibody, and use thereof in detecting the presence or level of tPINP in a sample.
