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1.发明授权Lysosomal phospholipase A2 (LPLA2) activity as a therapeutic target for treating systemic lupus erythematosus 有权溶酶体磷脂酶A2（LPLA2）活性作为治疗系统性红斑狼疮的治疗靶点公开(公告)号：US09309553B2
公开(公告)日：2016-04-12
申请号：US13272949
申请日：2011-10-13
Applicant: James A. Shayman , Akira Abe , Robert Kelly , Jessica Kollmeyer , Ye Lu
Inventor： James A. Shayman , Akira Abe , Robert Kelly , Jessica Kollmeyer , Ye Lu
CPC classification number: A61K38/45 , A61K38/465 , C12Q1/44 , C12Y203/01 , C12Y301/01005 , G01N33/6854 , G01N2333/91051 , G01N2333/918 , G01N2800/104 , G01N2800/56
Abstract: The present invention is directed to methods for diagnosis and treatment of systemic lupus erythematosus and drug-induced systemic lupus erythematosus. More specifically, the specification describes methods using a lysosomal phospholipase A2 in methods for the diagnosis and treatment of autoimmune disorders such as systemic lupus erythematosus and drug-induced systemic lupus erythematosus.
Abstract translation: 本发明涉及用于诊断和治疗系统性红斑狼疮和药物诱发的系统性红斑狼疮的方法。 更具体地，本说明书描述了在诊断和治疗诸如系统性红斑狼疮和药物诱发的系统性红斑狼疮的自身免疫疾病的方法中使用溶酶体磷脂酶A2的方法。
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公开(公告)号：US07798156B2
公开(公告)日：2010-09-21
申请号：US11353411
申请日：2006-02-13
Applicant: Robert Kelly
Inventor： Robert Kelly
CPC classification number: A46B7/023 , A46B5/06 , A46B2200/01 , A46B2200/1066
Abstract: Brushcards are provided. The brushcards include a planar member having a plurality of sections, each separated by lines of weakness, each section having a handle region and a bristle region. The planar member includes at least one recess, and the member is configured to fold into a toothbrush.
Abstract translation: 提供刷卡。 刷卡包括具有多个部分的平面部件，每个部分由弱线分开，每个部分具有手柄区域和刷毛区域。 平面构件包括至少一个凹部，并且构件构造成折叠成牙刷。
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公开(公告)号：US07204534B2
公开(公告)日：2007-04-17
申请号：US10738125
申请日：2003-12-16
Applicant: Robert Kelly
Inventor： Robert Kelly
IPC: A47F13/06
CPC classification number: G08B29/145 , G08B17/113 , Y10T16/44
Abstract: The invention relates to a novel device for easy maintenance of smoke detectors, comprising a three dimensional “receptacle” that attaches to a pole and fits around a smoke detector housing to easily remove it from its mounting plate.
Abstract translation: 本发明涉及一种易于维护烟雾探测器的新型装置，包括一个三维“插座”，该三维“插座”连接到一个极上，并安装在烟雾探测器外壳周围，以便将其从其安装板上移除。
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公开(公告)号：US20050015620A1
公开(公告)日：2005-01-20
申请号：US10621408
申请日：2003-07-18
Applicant: John Edison , Robert Kelly
Inventor： John Edison , Robert Kelly
CPC classification number: G06Q30/06 , G06Q10/063
Abstract: A management system for determining the security measures of a plurality of vendors. An assessment is performed on a plurality of vendors at a discount. The assessment is placed into a database and is reviewable and accessible by clients who subscribe to the management system. The management system allows clients to review and assess the security information regarding a plurality of vendors without the cost of performing an assessment of each vendor.
Abstract translation: 一种用于确定多个供应商的安全措施的管理系统。 以折扣方式对多个供应商进行评估。 评估被放入数据库中，并且可以由订阅管理系统的客户进行审阅和访问。 管理系统允许客户审查和评估关于多个供应商的安全信息，而不需要对每个供应商进行评估的成本。
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公开(公告)号：US09157243B2
公开(公告)日：2015-10-13
申请号：US14487590
申请日：2014-09-16
Applicant: Robert Kelly
Inventor： Robert Kelly
CPC classification number: E04B1/703 , E04B2/02 , E04F13/007 , E04F17/04
Abstract: A plurality of devices used alone or in combination for releasing moisture from a building are provided. The devices are especially suitable for use in new or existing masonry and frame buildings with low-slope roofs, on parapet walls and mansard roofs, and on masonry walls and foundation walls. The devices give buildings adequate wall and roof system ventilation and moisture vapor release portals so as to better prevent mold and other water related damage. The devices may be used individually or in combination wherein the devices are placed on or against a parapet wall, masonry wall or foundation wall of a building. Further, the devices may be used in connection with a joist or truss system of a building to prevent moisture damage to the joists or truss system and to prevent compromises and other structural integrity problems to a building which often occur with moisture.
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公开(公告)号：US20080014807A1
公开(公告)日：2008-01-17
申请号：US11822187
申请日：2007-07-03
Applicant: Edward Auck , Robert Kelly
Inventor： Edward Auck , Robert Kelly
IPC: B63H21/32
CPC classification number: B63H21/32 , F01N13/004 , F01N13/12 , F01N2240/36 , F01N2590/022
Abstract: The present invention is a reversion control device including a housing with a proximal end and a distal end. The reversion control device further includes at least one reversion cone, a stationary vane and a flapper. In one example, the reversion control device includes an oxygen sensor for monitoring the oxygen content of the engine for routine operations or for diagnostic purposes. In an example, the housing includes an expansion chamber to house the reversion cone, the stationary vane and the flapper. In another example, the stationary vane is housed within the reversion cone. In yet another example, the reversion control device is integrated within an exhaust manifold elbow.
Abstract translation: 本发明是一种逆转控制装置，其包括具有近端和远端的壳体。 还原控制装置还包括至少一个反转锥体，固定叶片和挡板。 在一个示例中，逆转控制装置包括氧传感器，用于监测用于常规操作或用于诊断目的的发动机的氧含量。 在一个示例中，壳体包括用于容纳逆转锥体，固定叶片和挡板的膨胀室。 在另一个实例中，固定叶片容纳在回转锥体内。 在另一个示例中，回退控制装置集成在排气歧管弯头内。
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公开(公告)号：US20070207097A1
公开(公告)日：2007-09-06
申请号：US11707044
申请日：2007-02-16
Applicant: Robert Kelly , Alisa Roddick-Lanzilotta , Sigrid Vorwerk , Luisa Coderch
Inventor： Robert Kelly , Alisa Roddick-Lanzilotta , Sigrid Vorwerk , Luisa Coderch
IPC: A61K8/37
Abstract: Animal or human hair or nails, eyelashes or eyebrows are treated with internal wool lipid extract.
Abstract translation: 用内部羊毛脂提取物处理动物或人的头发或指甲，睫毛或眉毛。
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8.发明申请Keratin and soluble derivatives thereof for a nutraceutical and to reduce oxidative stress and to reduce inflammation and to promote skin health 有权角蛋白及其可溶性衍生物，用于营养药物并降低氧化应激并减少炎症并促进皮肤健康
公开(公告)号：US20070065506A1
公开(公告)日：2007-03-22
申请号：US11370063
申请日：2006-03-08
Applicant: Robert Kelly , Gregory Ellis , Rebecca Macdonald , Robert McPherson , Paul Middlewood , Mark Nuthall , Guang-Feng Rao , Alisa Roddick-Lanzilotta , Gudmundur Sigurjonsson , Diane Singleton
Inventor： Robert Kelly , Gregory Ellis , Rebecca Macdonald , Robert McPherson , Paul Middlewood , Mark Nuthall , Guang-Feng Rao , Alisa Roddick-Lanzilotta , Gudmundur Sigurjonsson , Diane Singleton
CPC classification number: A61K38/1709 , A61K31/375 , A61K31/717 , A61K33/00 , A61K2300/00
Abstract: Keratin and derivatives thereof, preferably S-sulfonated keratin intermediate filament protein, S-sulfonated keratin high sulfur protein, and S-sulfonated peptides provide antioxidant activity, e.g., that equal to 200-2200 μmol TEAC/100 g or 100 ml, and are useful in an oral supplement to cause reduction in oxidative stress and benefits stemming therefrom, e.g., promoting skin health and to provide anti-inflammatory effect.
Abstract translation: 角蛋白及其衍生物，优选S-磺化角蛋白中间丝蛋白，S-磺化角蛋白高硫蛋白和S-磺化肽提供抗氧化活性，例如等于200-2200mumol TEAC / 100g或100毫升，并且 可用于口服补充剂以引起氧化应激和由此产生的益处，例如促进皮肤健康并提供抗炎作用。
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公开(公告)号：US20060165635A1
公开(公告)日：2006-07-27
申请号：US10536325
申请日：2003-11-28
Applicant: Robert Kelly , Alisa Roddick-Lanzilotta
Inventor： Robert Kelly , Alisa Roddick-Lanzilotta
CPC classification number: A61K8/65 , A61Q1/02 , A61Q1/06 , A61Q1/10 , A61Q3/02 , A61Q5/02 , A61Q5/04 , A61Q5/06 , A61Q5/065 , A61Q5/12 , A61Q9/02 , A61Q19/00 , A61Q19/002 , A61Q19/08 , A61Q19/10
Abstract: A range of personal care products that include a keratin protein fraction. The fraction may be intact or hydrolysed. It is preferably S-sulfonated. The content of the fraction may range from 0.001% to 50%. In most formulations its content will be less than 1% although in certain products such as nail care products the content will be higher. A wide range of personal care products are described including shampoos, body gels and lotions, conditioners, creams and cosmetics generally.
Abstract translation: 一系列包括角质蛋白级分的个人护理产品。 馏分可以是完整的或水解的。 优选S-磺化。 级分的含量可以在0.001％至50％的范围内。 在大多数制剂中，其含量将不到1％，尽管某些产品如指甲护理产品的含量会更高。 描述了广泛的个人护理产品，包括洗发剂，凝胶和乳液，调理剂，霜剂和化妆品。
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公开(公告)号：US09157244B1
公开(公告)日：2015-10-13
申请号：US14738841
申请日：2015-06-13
Applicant: Robert Kelly
Inventor： Robert Kelly
CPC classification number: E04B1/703 , E04B2/02 , E04F13/007 , E04F17/04
Abstract: A plurality of devices used alone or in combination for releasing moisture from a building are provided. The devices are especially suitable for use in new or existing masonry and frame buildings with low-slope roofs, on parapet walls and mansard roofs, and on masonry walls and foundation walls. The devices give buildings adequate wall and roof system ventilation and moisture vapor release portals so as to better prevent mold and other water related damage. The devices may be used individually or in combination wherein the devices are placed on or against a parapet wall, masonry wall or foundation wall of a building. Further, the devices may be used in connection with a joist or truss system of a building to prevent moisture damage to the joists or truss system and to prevent compromises and other structural integrity problems to a building which often occur with moisture.
Abstract translation: 提供了单独使用或组合使用以从建筑物释放水分的多个装置。 这些设备特别适用于新建或现有的砌体和框架建筑物，其中包括低坡屋顶，护栏墙和人造屋顶以及砖石墙和基础墙。 这些设备为建筑物提供足够的墙壁和屋顶系统通风和湿气释放入口，以更好地防止模具和其他与水有关的损坏。 这些装置可以单独使用或组合使用，其中将装置放置在建筑物的栏杆壁，砖石墙壁或基础墙壁上或靠在墙壁上。 此外，这些装置可以与建筑物的托梁或桁架系统结合使用，以防止对托梁或桁架系统的水分损伤，并且防止对经常与水分发生的建筑物的折衷和其他结构完整性问题。
