-
公开(公告)号：US20230303718A1
公开(公告)日：2023-09-28
申请号：US18163484
申请日：2023-02-02
Applicant: NYKODE THERAPEUTICS ASA
Inventor： Bjarne BOGEN , Agnete Brunsvik FREDRIKSEN , Inger SANDLIE
IPC: C07K16/44 , C07K16/28 , C07K14/005 , C07K14/34 , C07K14/705 , C07K14/715 , C12N9/12
CPC classification number: C07K16/44 , C07K16/2833 , C07K14/005 , C07K14/34 , C07K14/70578 , C07K14/7158 , C07K16/28 , C12N9/1276 , A61K2039/505
Abstract: Recombinant antibody-based molecules that trigger both T-cell and B-cell immune responses are disclosed. The recombinant molecules are comprised by at least one targeting unit and at least one antigenic unit connected through a dimerization motif. Also disclosed are nucleic acid molecules encoding the recombinant antibody-based molecule and methods of treating multiple myeloma or lymphoma in a patient using the recombinant antibody-based molecules or the nucleic acid molecules.
-
公开(公告)号：US20230048561A1
公开(公告)日：2023-02-16
申请号：US17689076
申请日：2022-03-08
Applicant: NYKODE THERAPEUTICS ASA
Inventor： Bjarne BOGEN , Agnete B. FREDRICKSEN , Inger SANDLIE
IPC: C07K16/44 , C07K16/28 , C07K14/005 , C07K14/34 , C07K14/705 , C07K14/715 , C12N9/12
Abstract: Recombinant antibody-based molecules that trigger both T-cell and B-cell immune responses are disclosed. The recombinant molecules are comprised by at least one targeting unit and at least one antigenic unit connected through a dimerization motif. Also disclosed are nucleic acid molecules encoding the recombinant antibody-based molecule and methods of treating multiple myeloma or lymphoma in a patient using the recombinant antibody-based molecules or the nucleic acid molecules.
