MODIFIED CHANNEL RHODOPSIN
    3.
    发明申请

    公开(公告)号:US20210347831A1

    公开(公告)日:2021-11-11

    申请号:US17277468

    申请日:2019-09-15

    Abstract: An object of the present invention is to provide a modified channel rhodopsin capable of opening and closing an ion channel by irradiation with light at different wavelengths, and/or having high ion permeability (photoreactivity). The solution is to substitute a C-terminal region of a channel rhodopsin obtained by substituting an N-terminal region of a Volvox carteri-derived channel rhodopsin by an N-terminal region of a Chlamydomonas reinhardtii-derived channel rhodopsin-1, by a C-terminal region of a Chlamydomonas reinhardtii-derived channel rhodopsin-2 or a C-terminal region of a Tetraselmis striata-derived channel rhodopsin.

Patent Agency Ranking