公开(公告)号：US20160223562A1

公开(公告)日：2016-08-04

申请号：US15074214

申请日：2016-03-18

Applicant: JPT Peptide Technologies GmbH

Inventor： Johannes Zerweck ,  Mike Schutkowski ,  Holger Wenschuh

IPC: G01N33/68

CPC classification number: G01N33/6848 ,  C07K2/00 ,  G01N33/68 ,  G01N2458/15 ,  G01N2560/00

Abstract: The present invention is related to a method for preparing an internal peptide standard, comprising a) providing a first tag, and b) coupling of a first peptide to the first tag, whereby the first peptide comprises an amino acid sequence, or a) providing a first tag and b) coupling to the first tag the amino acids forming the first peptide comprising an amino acid sequence, whereby the C-terminal end of the amino acid sequence of the first peptide corresponds to the C-terminal end generated by a sequence-specific hydrolysis of an amide bond, ester bond or thioester bond preferably of an amide bond of a peptide.