公开(公告)号：US20190210003A1

公开(公告)日：2019-07-11

申请号：US15520390

申请日：2015-10-01

Applicant: JNC CORPORATION

Inventor： Natuki OKANIWA ,  Tsuyoshi NAKAMA ,  Eri IWAMOTO ,  Shuji SASAKI ,  Takuo IKEDA

IPC: B01J20/24 ,  B01J20/28 ,  B01J20/285 ,  B01J20/30 ,  B01D15/36 ,  B01J41/16 ,  B01J41/07 ,  C08B15/00 ,  C08B15/06 ,  C08J9/28 ,  B01J20/281

CPC classification number: B01J20/24 ,  B01D15/361 ,  B01J20/28042 ,  B01J20/281 ,  B01J20/285 ,  B01J20/30 ,  B01J20/305 ,  B01J20/3085 ,  B01J41/05 ,  B01J41/07 ,  B01J41/16 ,  B01J2220/52 ,  C07K1/16 ,  C07K1/18 ,  C08B15/005 ,  C08B15/06 ,  C08J9/26 ,  C08J9/28 ,  C08J2201/026 ,  C08J2301/12 ,  G01N30/482 ,  G01N30/88 ,  G01N2030/484

Abstract: Provided is a manufacturing method for monolithic structure that is a porous body formed of polysaccharide being a naturally-occurring polymer, has continuous pores with an average pore diameter suitable for biomolecule separation, and allows formation into arbitrary shape. The polysaccharide monolithic structure is manufactured by a method including a first step of obtaining a polysaccharide solution by dissolving polysaccharide into a mixed solvent of a first component and a second component at temperature lower than a boiling point of the mixed solvent, and a second step of obtaining polysaccharide monolithic structure by cooling the polysaccharide solution, wherein the first component is a solvent selected from lactate, and the second component is a solvent selected from water, lower alcohol, and a combination thereof. The monolithic structure obtained is a porous body having continuous pores with an average pore diameter of 0.01 to 20.0 micrometers, and a thickness of 100 micrometers or more.