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1.
公开(公告)号:US20150315198A1
公开(公告)日:2015-11-05
申请号:US14703848
申请日:2015-05-04
Applicant: Global Blood Therapeutics, Inc.
Inventor: Zhe Li , Qing Xu , Chul Yu , Calvin Yee , Stephen L. Gwaltney,, II , Brian W. Metcalf , Steven Richards , Matthew A. Lardy , Lina Setti , Hing Sham
IPC: C07D487/04 , C07D471/04
CPC classification number: C07D471/04 , C07D487/04 , C07D519/00
Abstract: In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.
Abstract translation: 一方面,本发明一般涉及式及其分式,或其各自的互变异构体,其各自的药学上可接受的盐或上述各自的药学上可接受的溶剂合物,其中X1,L1,L3 和R3在本文中描述。
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公开(公告)号:US09695166B2
公开(公告)日:2017-07-04
申请号:US14703848
申请日:2015-05-04
Applicant: Global Blood Therapeutics, Inc.
Inventor: Zhe Li , Qing Xu , Chul Yu , Calvin Yee , Stephen L. Gwaltney, II , Brian W. Metcalf , Steven Richards , Matthew A. Lardy , Lina Setti , Hing Sham
IPC: C07D471/04 , C07D487/04 , C07D519/00 , A61K31/437 , A61K31/4162
CPC classification number: C07D471/04 , C07D487/04 , C07D519/00
Abstract: In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.