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公开(公告)号：US20210332348A1
公开(公告)日：2021-10-28
申请号：US17237495
申请日：2021-04-22
Inventor： Xiang CHEN , Lei WANG , Su LI , Longtang ZHENG , Yanan WANG , Fei WEN , Juan XIN , Wentian ZHANG , Jing CHENG
IPC: C12N15/10 , C12Q1/6806
Abstract: A nucleic acid extraction composition, reagents and kits containing the same and uses thereof. Provided is a nucleic acid extraction and purification reagent free of volatile organic solvents, which prevents the damage of volatile organic solvents to people and greatly improves the timeliness of nucleic acid extraction and purification, making the operation extremely simple, and the nucleic acid can be obtained within 10 minutes. The obtained nucleic acid may be used for biological reactions such as PCR, NASBA, LAMP and RPA. Moreover, the reagents of the present disclosure may be used to extract nucleic acids of cells, bacteria, fungi, DNA viruses and RNA viruses from various samples such as blood, throat swab preserving fluid, saliva, urine, sputum, excrement and the like, and very suitable for clinical and scientific research uses.
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公开(公告)号：US20210322980A1
公开(公告)日：2021-10-21
申请号：US17249398
申请日：2021-03-01
Applicant: CAPITALBIO CORPORATION
Inventor： Lei WANG , Liang BAI , Xiang CHEN , Tengfei GUO , Xinying ZHOU , Jing CHENG , Fei WEN , Yanan WANG , Longtang ZHENG , Peng LIU , Baolian LI , Youchun XU , Bin ZHUANG , Wanli XING
IPC: B01L3/00
Abstract: A whole-process biological detection device is provided. The whole-process biological detection device belongs to the technical field of biological detection, and includes at least one reactor, where the reactor includes at least one sample-loading unit, at least one liquid release-control unit, at least one extraction unit, at least one liquid switch-control unit, at least one liquid collection unit, at least one liquid transfer unit, at least one liquid flow-control unit, at least one liquid quantitative dispersion unit and multiple reaction cells. The product of the solution has the characteristics of high integration, no need for additional reagents, simple operation, stable and reliable, etc., thereby achieving the goal of sealing the whole process of biological detection and effectively avoiding cross-contamination between samples and equipment.
