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公开(公告)号：US20170100386A1
公开(公告)日：2017-04-13
申请号：US15288400
申请日：2016-10-07
Applicant: AbbVie S.à.r.l. , Galapagos NV
Inventor： Rhalid Akkari , Luke Jonathan Alvey , Xavier Marie Bock , Brian S. Brown , Pieter Isabelle Roger Claes , Marlon D. Cowart , Katja E. Conrath , Douglas Cyr , Elsa De Lemos , Gert Jules Hector De Wilde , Nicolas Desroy , Béranger Duthion , Gregory A. Gfesser , Romain Luc Marie Gosmini , Christopher Gaëtan Housseman , Koen Karel Jansen , Jianguo Ji , Philip R. Kym , Jean-Michel Lefrancois , Oscar Mammoliti , Christel Jeanne Marie Menet , Nuria Merayo Merayo , Gregory John Robert Newsome , Adeline Marie Elise Palisse , Sachin V. Patel , Mathieu Rafaël Pizzonero , Anurupa Shrestha , Elizabeth C. Swift , Chris Tse , Steven Emiel Van der Plas , Xueqing Wang
IPC: A61K31/4545 , G01N33/50 , A61K45/06
CPC classification number: A61K31/4545 , A61K45/06 , C07D471/04 , C07D519/00 , G01N33/5023 , G01N2800/382
Abstract: A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of cystic fibrosis.
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公开(公告)号：US10130622B2
公开(公告)日：2018-11-20
申请号：US15288400
申请日：2016-10-07
Applicant: AbbVie S.à.r.l. , Galapagos NV
Inventor： Rhalid Akkari , Luke Jonathan Alvey , Xavier Marie Bock , Brian S. Brown , Pieter Isabelle Roger Claes , Marlon D. Cowart , Katja E. Conrath , Douglas Cyr , Elsa De Lemos , Gert Jules Hector De Wilde , Nicolas Desroy , Béranger Duthion , Gregory A. Gfesser , Romain Luc Marie Gosmini , Christopher Gaëtan Housseman , Koen Karel Jansen , Jianguo Ji , Philip R. Kym , Jean-Michel Lefrancois , Oscar Mammoliti , Christel Jeanne Marie Menet , Nuria Merayo Merayo , Gregory John Robert Newsome , Adeline Marie Elise Palisse , Sachin V. Patel , Mathieu Rafaël Pizzonero , Anurupa Shrestha , Elizabeth C. Swift , Chris Tse , Steven Emiel Van der Plas , Xueqing Wang
IPC: A61K31/437 , A61K31/4545 , C07D471/04 , C07D519/00 , A61K45/06 , G01N33/50
Abstract: A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of cystic fibrosis.
