-
公开(公告)号：US07585976B2
公开(公告)日：2009-09-08
申请号：US11340256
申请日：2006-01-26
Applicant: Silvio A. Campagna , Francis G. Fang , James J. Kowalczyk , Shawn Schiller , Boris M. Seletsky , Mark Spyvee , Hu Yang
Inventor： Silvio A. Campagna , Francis G. Fang , James J. Kowalczyk , Shawn Schiller , Boris M. Seletsky , Mark Spyvee , Hu Yang
IPC: C07D215/14
CPC classification number: C07D207/04 , C07D207/12 , C07D207/16 , C07D207/42 , C07D209/20 , C07D211/60 , C07D217/26 , C07D223/06 , C07D233/84 , C07D237/04 , C07D241/04 , C07D265/30 , C07D277/06 , C07D279/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D405/12 , C07D471/04 , C07K5/0205 , C07K5/0207 , C07K5/0821
Abstract: The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.
Abstract translation: 本发明提供具有式（I）的化合物：另外提供其合成方法及其用于治疗癌症的方法，其中R1-R7，X1，X2，R，Q和n如本文所定义 。
-
2.发明授权
公开(公告)号：US08350059B2
公开(公告)日：2013-01-08
申请号：US12746672
申请日：2008-12-08
Applicant: Roch Boivin , Silvio A. Campagna , Hong Du , Francis G. Fang , Thomas Horstmann , Charles-Andre Lemelin , Jing Li , Pamela McGuinness , Xiang Niu , Matthew J. Schnaderbeck , Kevin (kuo-ming) Wu , Xiaojie (jeff) Zhu
Inventor： Roch Boivin , Silvio A. Campagna , Hong Du , Francis G. Fang , Thomas Horstmann , Charles-Andre Lemelin , Jing Li , Pamela McGuinness , Xiang Niu , Matthew J. Schnaderbeck , Kevin (kuo-ming) Wu , Xiaojie (jeff) Zhu
IPC: C07D493/00
CPC classification number: C07D313/00 , C07D317/22 , C07D317/24 , C07D317/30 , C07D319/08 , C07D493/04 , Y02P20/55
Abstract: Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.
Abstract translation: 本文公开了可用于制备大环内酯类的方法和中间体，例如其中R 1 -R 12如本文所定义的式（IV）化合物。
-
3.发明申请INTERMEDIATES AND METHODS FOR MAKING ZEARALENONE MACROLIDE ANALOGS 有权制备ZEARALENONE MACROLIDE ANALOGS的中间体和方法
公开(公告)号：US20110237805A1
公开(公告)日：2011-09-29
申请号：US12746672
申请日：2008-12-08
Applicant: Roch Boivin , Silvio A. Campagna , Hong Du , Francis G. Fang , Thomas Horstmann , Charles-Andre Lemelin , Jing Li , Pamela Mcguinness , Xiang Niu , Matthew J. Schnaderbeck , Kevin (kuo-ming) Wu , Xiaojie (Jeff) Zhu
Inventor： Roch Boivin , Silvio A. Campagna , Hong Du , Francis G. Fang , Thomas Horstmann , Charles-Andre Lemelin , Jing Li , Pamela Mcguinness , Xiang Niu , Matthew J. Schnaderbeck , Kevin (kuo-ming) Wu , Xiaojie (Jeff) Zhu
IPC: C07D313/00
CPC classification number: C07D313/00 , C07D317/22 , C07D317/24 , C07D317/30 , C07D319/08 , C07D493/04 , Y02P20/55
Abstract: Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.
Abstract translation: 本文公开了可用于制备大环内酯类的方法和中间体，例如其中R 1 -R 12如本文所定义的式（IV）化合物。
-
公开(公告)号：US20080108820A1
公开(公告)日：2008-05-08
申请号：US10572871
申请日：2004-09-22
Applicant: Silvio A. Campagna , Francis G. Fang , James J. Kowalczyk , Shawn Schiller , Boris M. Seletsky , Mark Spyvee , Hu Yang
Inventor： Silvio A. Campagna , Francis G. Fang , James J. Kowalczyk , Shawn Schiller , Boris M. Seletsky , Mark Spyvee , Hu Yang
IPC: C07D211/60 , C07D277/06
CPC classification number: C07D207/04 , C07D207/12 , C07D207/16 , C07D207/42 , C07D209/20 , C07D211/60 , C07D217/26 , C07D223/06 , C07D233/84 , C07D237/04 , C07D241/04 , C07D265/30 , C07D277/06 , C07D279/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D405/12 , C07D471/04 , C07K5/0205 , C07K5/0207 , C07K5/0821
Abstract: The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.
Abstract translation: 本发明提供具有式（I）的化合物：另外提供其合成方法及其用于治疗癌症的方法，其中R 1 -R 7 X 1，X 2，R 3，Q 3和n如本文所定义。
