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公开(公告)号：US12128256B2
公开(公告)日：2024-10-29
申请号：US18464499
申请日：2023-09-11
Applicant: Profound Medical Inc.
Inventor： Ron Kurtz , Patrick Leonard , Xiaoyu Zhang
CPC classification number: A61N7/02 , A61B2090/374 , A61N2007/0078 , A61N2007/0095 , A61N2007/025
Abstract: Methods for reducing electromagnetic interference arising from use of multiple ultrasound transducers in an array, particularly inside a human body that is inside a magnetic resonance imaging device. Electrical signals driving the transducers are offset in phase with respect to one another so as to achieve maximum offset of electrical and magnetic fields arising from such signals and transducers. Phase offsets are dynamically adjusted to respond to changes in driving amplitudes and frequencies so as to maintain optimal reduction of electromagnetic interference.
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公开(公告)号：US20230072545A1
公开(公告)日：2023-03-09
申请号：US18055552
申请日：2022-11-15
Applicant: Profound Medical Inc.
Inventor： Levant Tinaz , Patrick Leonard , Xiaoyu Zhang , Ron Kurtz , Mathieu Allard
Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.
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3.发明授权
公开(公告)号：US11471053B2
公开(公告)日：2022-10-18
申请号：US15797075
申请日：2017-10-30
Applicant: Profound Medical Inc.
Inventor： Alexandre Bigot , Patrick Leonard , Ron Kurtz
Abstract: Temperature uncertainty maps are calculated based on a rolling window of temperature maps, which is updated as new temperature maps are generated. The rolling window mitigates the effect of transient motion during a thermal therapy procedure. A clinician or an automated control system can then update a portion of an anatomical boundary or the thermal therapy applicator center based on the temperature uncertainty map.
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公开(公告)号：US20220096872A1
公开(公告)日：2022-03-31
申请号：US17643518
申请日：2021-12-09
Applicant: Profound Medical Inc.
Inventor： Aaro Tuominen
Abstract: An apparatus for controlling the angular direction of energy emitted from a plurality of energy delivery devices. The apparatus includes a plurality of rods, each rod mechanically coupled to one of the energy delivery devices, to a stationary plate, and to a moveable plate. The stationary plate includes holes that are configured to receive a portion of a first rotatable joint that is mechanically coupled to each rod. The moveable plate includes holes that are configured to receive a portion of a second rotatable joint, the second rotatable joint slidingly engaging a portion of the respective rod. The angle of each rod changes when the moveable plate is moved in any direction with respect to the stationary plate. Changing the rod angle changes the angular direction of the energy emitted from the energy delivery devices such that the energy passes through an intended focal position.
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公开(公告)号：US11224768B2
公开(公告)日：2022-01-18
申请号：US15981383
申请日：2018-05-16
Applicant: Profound Medical Inc.
Inventor： Aaro Tuominen
Abstract: An apparatus for controlling the angular direction of energy emitted from a plurality of energy delivery devices. The apparatus includes a plurality of rods, each rod mechanically coupled to one of the energy delivery devices, to a stationary plate, and to a moveable plate. The stationary plate includes holes that are configured to receive a portion of a first rotatable joint that is mechanically coupled to each rod. The moveable plate includes holes that are configured to receive a portion of a second rotatable joint, the second rotatable joint slidingly engaging a portion of the respective rod. The angle of each rod changes when the moveable plate is moved in any direction with respect to the stationary plate. Changing the rod angle changes the angular direction of the energy emitted from the energy delivery devices such that the energy passes through an intended focal position.
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公开(公告)号：US11191444B2
公开(公告)日：2021-12-07
申请号：US15788414
申请日：2017-10-19
Applicant: Profound Medical Inc.
Inventor： Alexandre Bigot , Patrick Leonard
Abstract: In one aspect, a method comprises: receiving data indicative of at least one phase image captured using a magnetic resonance imaging (MRI) device during delivery of thermal therapy by a thermal therapy applicator to a target volume within a patient's body; and processing said at least one phase image; wherein said processing said at least one phase image comprises: applying a first mask; applying phase unwrap; and applying a second mask.
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公开(公告)号：US10046180B2
公开(公告)日：2018-08-14
申请号：US14431932
申请日：2013-09-25
Applicant: Profound Medical Inc.
Inventor： Jaakko Juhani Tolo
Abstract: The invention provides for a medical apparatus (200, 400, 500) comprising a high intensity focused ultrasound system (206). Machine executable instructions (260, 262, 264, 266, 408, 526) in a memory (250) cause a processor (244) to: receive (100) location data (252) descriptive of multiple sonication points (224, 226, 228, 230); determine (102) a sonication path (254) for each of the multiple sonication points using a geometric transducer element model (262); detect (104) an overlap region (256, 306) using the sonication path in the near field region; determine (106) transducer control commands (258) using the overlap region, wherein the transducer commands are operable to control the multiple transducer elements to reduce the deposition of ultrasonic energy in the overlap region during sonication of the two or more sonication points; and control (108) the high intensity focused ultrasound system using the transducer control commands.
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公开(公告)号：US10010727B2
公开(公告)日：2018-07-03
申请号：US14781598
申请日：2014-04-04
Applicant: Profound Medical Inc.
Inventor： Max Oskar Kohler
CPC classification number: A61N7/022 , A61B5/055 , A61B8/12 , A61B2090/374 , A61N2007/0078 , A61N2007/0095
Abstract: The invention provides for a medical apparatus (300) comprising: a magnetic resonance imaging system (302); an ultrasonic system (322) for connecting to a catheter (324, 504, 600) with an ultrasound array (400, 402, 404, 508, 602, 604). The ultrasonic system is operable for driving the ultrasound array. Machine executable instructions (354, 356, 358) cause a processor (334) for controlling the medical apparatus to: generate (100, 202) at least one acoustic radiation impulse with the ultrasonic system, wherein the generated ultrasound energy is below a predetermined level; acquire (102, 204) the magnetic resonance data using an acoustic radiation force imaging pulse sequence; reconstruct (104, 206) at least one acoustic radiation force pulse image using the magnetic resonance data; and determine (106, 208) an energy deposition zone for the catheter using at least partially the at least one acoustic radiation force pulse image.
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公开(公告)号：US11944847B2
公开(公告)日：2024-04-02
申请号：US16984367
申请日：2020-08-04
Applicant: Profound Medical Inc.
Inventor： Mathieu Allard
IPC: A61N7/00
CPC classification number: A61N7/00 , A61N2007/0004 , A61N2007/0043 , A61N2007/0052 , A61N2007/0078 , A61N2007/0086
Abstract: A method for delivering ultrasound therapy using open-loop controls comprises inserting a distal tip of a therapeutic ultrasound applicator into a patient's urethra, the distal tip including an ultrasound transducer; acquiring ultrasound images of the patient's urethra and prostate with an ultrasound imaging probe; aligning the distal tip of the therapeutic ultrasound applicator with the patient's prostate using the ultrasound images; delivering therapeutic ultrasound energy to the patient's prostate, with the ultrasound transducer, according to a treatment plan, the treatment plan including a predetermined limited angular range for the therapeutic ultrasound energy that avoids the patient's rectum and neurovascular bundles, wherein the therapeutic ultrasound is delivered without temperature feedback data.
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公开(公告)号：US11819713B2
公开(公告)日：2023-11-21
申请号：US18055552
申请日：2022-11-15
Applicant: Profound Medical Inc.
Inventor： Levant Tinaz , Patrick Leonard , Xiaoyu Zhang , Ron Kurtz , Mathieu Allard
CPC classification number: A61N7/02 , B06B1/0276 , B06B1/0607 , A61N2007/0073 , A61N2007/0078 , B06B2201/76
Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.
