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公开(公告)号：US20160367478A1
公开(公告)日：2016-12-22
申请号：US15186977
申请日：2016-06-20
Applicant: Harsha Chigurupati
Inventor： Harsha Chigurupati , Manish Radheshyam Biyani , Biswajit Auddy , Shrabana Chakrabarti
IPC: A61K9/00 , A61K38/05 , A23L2/52 , A61K31/047 , A61K47/12 , A61K31/704 , A61K38/01
CPC classification number: A61K9/0095 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/18 , A23V2002/00 , A61K31/047 , A61K31/704 , A61K38/018 , A61K38/05 , A61K47/12 , A23V2200/334 , A23V2250/21 , A23V2250/55 , A23V2250/64
Abstract: Disclosed is a synergistic beverage composition for alleviating alcohol-induced oxidative stress, hepatic stress, CNS stress, veisalgia and modulating immunology parameters. The composition includes saponin glycoside, amino acid derivative and sugar or sugar alcohol as active ingredients and pH adjusting agents and flavouring agents as inactive ingredients. The calculated proportions of amino acid derivatives, Saponin glycoside and sugar or sugar alcohol in the alcohol exhibit synergistic effects, thereby alleviating oxidative stress, hepatic stress, CNS stress, veisalgia and modulating immunology parameters, which could ultimately leads to prevention of alcohol-induced damage or impairment of organs, which could be temporary or permanent.
Abstract translation: 公开了用于减轻酒精诱导的氧化应激，肝应激，CNS应激，维持麻醉和调节免疫学参数的协同饮料组合物。 该组合物包括皂苷苷，氨基酸衍生物和糖或糖醇作为活性成分和pH调节剂和调味剂作为惰性成分。 氨基酸衍生物，皂苷苷和糖或糖醇在醇中的计算比例表现出协同效应，从而减轻氧化应激，肝应激，CNS应激，维持麻醉和调节免疫学参数，这可能最终导致酒精诱发损伤的预防 或器官的损伤，这可能是暂时的或永久性的。
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公开(公告)号：US20170362394A1
公开(公告)日：2017-12-21
申请号：US15626712
申请日：2017-06-19
Applicant: Harsha Chigurupati
Inventor： Harsha Chigurupati , Manish Radheshyam Biyani , Biswajit Auddy , Shrabana Chakrabarti
IPC: C08H7/00 , A61K31/7028 , A61K31/047 , A61K31/197 , C07K5/062 , C01B25/30
CPC classification number: C08H6/00 , A61K31/047 , A61K31/197 , A61K31/198 , A61K31/7004 , A61K31/7028 , A61K31/704 , A61K38/018 , A61K38/05 , A61K38/063 , A61P1/16 , A61P25/00 , A61P25/32 , C01B25/30 , C07K5/06026 , A61K2300/00 , A61K38/00
Abstract: Provided herein is a composition to reduce DNA and hepatic damage and to enhance repair thereof. More particularly the composition includes a combination of active ingredients which can be used in a beverage composition and also relates to a beverage composition including said synergistic composition of active ingredients, wherein each active ingredient in the combination composition and/or beverage composition in appropriate concentration synergistically reduces the DNA damage as well as hepatic damage due to alcohol consumption and/or due to other reasons. The composition also enhances repair of the DNA and hepatic which has already been damaged. The composition also synergistically reduces hangover, modulates and/or alleviates immunology parameters and CNS parameters due to alcohol consumption and due to other reasons. Further a beverage composition including above synergistic composition and method of preparation thereof is provided.
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公开(公告)号：US10456359B2
公开(公告)日：2019-10-29
申请号：US15186977
申请日：2016-06-20
Applicant: Harsha Chigurupati
Inventor： Harsha Chigurupati , Manish Radheshyam Biyani , Biswajit Auddy , Shrabana Chakrabarti
IPC: A61K9/00 , A61K38/05 , A61K31/047 , A61K47/12 , A61K31/704 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/18 , A61K38/01
Abstract: Disclosed is a synergistic beverage composition for alleviating alcohol-induced oxidative stress, hepatic stress, CNS stress, veisalgia and modulating immunology parameters. The composition includes saponin glycoside, amino acid derivative and sugar or sugar alcohol as active ingredients and pH adjusting agents and flavoring agents as inactive ingredients. The calculated proportions of amino acid derivatives, Saponin glycoside and sugar or sugar alcohol in the alcohol exhibit synergistic effects, thereby alleviating oxidative stress, hepatic stress, CNS stress, veisalgia and modulating immunology parameters, which could ultimately leads to prevention of alcohol-induced damage or impairment of organs, which could be temporary or permanent.
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公开(公告)号：US10039776B2
公开(公告)日：2018-08-07
申请号：US14852794
申请日：2015-09-14
Applicant: Harsha Chigurupati
Inventor： Harsha Chigurupati , Manish Radheshyam Biyani , Biswajit Auddy
IPC: A61K31/704 , A61K31/7004 , A61K31/7016 , A61K9/00 , A61K31/047 , A23L2/52 , C12G3/04 , C12G3/06
CPC classification number: A61K31/704 , A23L2/52 , A23V2002/00 , A61K9/0053 , A61K9/0095 , A61K31/047 , A61K31/7004 , A61K31/7016 , C12G3/04 , C12G3/06 , A23V2200/334 , A23V2250/252 , A23V2250/6418 , A23V2250/64 , A23V2250/628 , A61K2300/00
Abstract: The present invention relates to a hepato-protective beverage composition comprising a potable liquid, a primary hepato-protective agent comprising 18β-Glycyrrhizin or 18α-Glycyrrhizin or a combination thereof, and a complimentary hepato-protective agent comprising sugar or sugar alcohol or a combination thereof. The combination of effective amounts of the primary and complimentary hepato-protective agents provides hepato-protection and reduced toxicity caused by consumption of alcoholic beverages. The present invention also provides a beverage additive comprising these hepato-protective agents designed to be mixed with a potable liquid, providing the same beneficial results.
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公开(公告)号：US20180092934A1
公开(公告)日：2018-04-05
申请号：US15394117
申请日：2016-12-29
Applicant: Harsha CHIGURUPATI
Inventor： Manish Radheshyam BIYANI , Biswajit AUDDY , Shrabana CHAKRABARTI
IPC: A61K31/704 , A61K31/047 , A61K9/00 , C12G3/06
CPC classification number: A61K31/704 , A23L33/105 , A23L33/18 , A61K9/0095 , A61K31/047 , A61K31/70 , C12G3/06
Abstract: The invention discloses a composition for DNA protection. More particularly, the invention discloses a composition to reduce DNA damage, to repair the damaged DNA and to enhance the DNA repair wherein such DNA damage may be caused due to alcohol consumption or due to any other known or unknown reasons.
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公开(公告)号：US20170071963A1
公开(公告)日：2017-03-16
申请号：US14852794
申请日：2015-09-14
Applicant: Harsha Chigurupati
Inventor： Harsha Chigurupati , Manish Radheshyam Biyani , Biswajit Auddy
IPC: A61K31/704 , A23L2/52 , A61K31/7004 , A61K31/7016 , A61K9/00 , A61K31/047
CPC classification number: A61K31/704 , A23L2/52 , A23V2002/00 , A61K9/0053 , A61K9/0095 , A61K31/047 , A61K31/7004 , A61K31/7016 , C12G3/04 , C12G3/06 , A23V2200/334 , A23V2250/252 , A23V2250/6418 , A23V2250/64 , A23V2250/628 , A61K2300/00
Abstract: The present invention relates to a hepato-protective beverage composition comprising a potable liquid, a primary hepato-protective agent comprising 18β-Glycyrrhizin or 18α-Glycyrrhizin or a combination thereof, and a complimentary hepato-protective agent comprising sugar or sugar alcohol or a combination thereof. The combination of effective amounts of the primary and complimentary hepato-protective agents provides hepato-protection and reduced toxicity caused by consumption of alcoholic beverages. The present invention also provides a beverage additive comprising these hepato-protective agents designed to be mixed with a potable liquid, providing the same beneficial results.
Abstract translation: 本发明涉及包含饮用液体，包含18β-甘草甜素或18α-甘草酸或其组合的初级肝保护剂的肝保护性饮料组合物，以及包含糖或糖醇或组合的补充性肝保护剂 其中。 主要和补充的肝保护剂的有效量的组合提供肝脏保护和由含酒精饮料消耗引起的毒性降低。 本发明还提供一种饮料添加剂，其包含这些设计为与饮用液体混合的肝保护剂，提供相同的有益效果。
