公开(公告)号：US20170184565A1

公开(公告)日：2017-06-29

申请号：US15116319

申请日：2015-02-12

Applicant: Thomas M. ROBERTS ,  Haoxuan TONG ,  Jean J. ZHAO ,  John BLENIS ,  Dana-Farber Cancer Institute, Inc. ,  PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Inventor： Thomas M. Roberts ,  Haoxuan Tong ,  Jean Zhao ,  John Blenis

IPC: G01N33/50 ,  A61K45/06 ,  A61K31/58 ,  G01N33/574 ,  C12Q1/68

CPC classification number: G01N33/5011 ,  A61K31/58 ,  A61K45/06 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/5088 ,  G01N33/57492 ,  G01N2333/91215 ,  G01N2500/10

Abstract: The present invention is based, in part, on the identification of novel FI.3K-mTORCI-S6K 1 signaling pathway biomarkers predictive of responsiveness to anti-cancer therapies.