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公开(公告)号:US09248103B2
公开(公告)日:2016-02-02
申请号:US14380442
申请日:2013-02-21
IPC分类号: A61K9/50 , A01N25/26 , A61K8/24 , A61K8/19 , A23L1/03 , A61K9/16 , A61K8/02 , A61K31/10 , A61K31/167 , A61K31/18 , A61K31/195 , A61K31/40 , A61K31/426 , A61K31/4515 , A61K31/505 , A61K31/7048 , B05D3/12 , B05D5/04 , A61K8/44 , A61K8/46 , A61K8/67 , A61Q19/00 , A01N25/00 , A61K9/14
CPC分类号: A61K9/501 , A01N25/00 , A01N25/26 , A23L29/015 , A23V2002/00 , A61K8/0241 , A61K8/19 , A61K8/24 , A61K8/44 , A61K8/463 , A61K8/676 , A61K9/143 , A61K9/1611 , A61K9/5089 , A61K31/10 , A61K31/167 , A61K31/18 , A61K31/195 , A61K31/40 , A61K31/426 , A61K31/4515 , A61K31/505 , A61K31/7048 , A61K2800/412 , A61K2800/413 , A61K2800/49 , A61Q19/00 , B05D3/12 , B05D5/04 , A23V2250/1578
摘要: It is an object of the present invention to provide a method for improving the solubility of a poorly-soluble substance, which is capable of increasing the solubility of substantially all poorly-soluble substances. This is a method comprising coating the surface of a poorly-soluble substance particle with microparticles of a calcium compound such as calcium phosphate or calcium carbonate, and at least one selected from a pH adjuster and a surfactant, by applying mechanical energy thereto.
摘要翻译: 本发明的目的是提供一种提高难溶性物质的溶解性的方法,其能够增加基本上所有难溶性物质的溶解度。 这是通过向其中施加机械能,包括用钙化合物如磷酸钙或碳酸钙的微粒和选自pH调节剂和表面活性剂的至少一种来涂覆难溶性物质颗粒的表面的方法。
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公开(公告)号:US09034301B2
公开(公告)日:2015-05-19
申请号:US12594230
申请日:2008-04-08
CPC分类号: A61K8/24 , A61K8/55 , A61K33/24 , A61Q11/00 , C01B25/322
摘要: It is intended to provide a remineralization promoter for tooth enamel and a composition for an oral cavity, which can highly effectively promote the remineralization of tooth enamel and strongly inhibit dental caries. The remineralization promoter for tooth enamel and the composition for an oral cavity are characterized by containing amorphous hydroxyapatite and/or amorphized hydroxyapatite showing two peaks at 2θ=31 to 35° in X-ray diffraction. The amorphized hydroxyapatite is obtained by reacting calcium salt with phosphate in an aqueous solution and drying the reaction solution at a temperature of 10 to 70° C.
摘要翻译: 旨在提供用于牙釉质的再矿化促进剂和用于口腔的组合物,其可以高度有效地促进牙釉质的再矿化并且强烈抑制龋齿。 用于牙釉质的再矿化促进剂和口腔组合物的特征在于含有无定形羟基磷灰石和/或非晶化羟基磷灰石,其在2θ处显示两个峰;在X射线衍射中为31至35°。 无定形羟基磷灰石是通过在水溶液中使钙盐与磷酸盐反应得到的,并在10-70℃的温度下干燥反应溶液。
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3.
公开(公告)号:US09023398B2
公开(公告)日:2015-05-05
申请号:US13497637
申请日:2010-09-10
CPC分类号: A61K9/143 , A01N25/08 , A01N25/26 , A23L29/015 , A23P20/10 , A61K9/501 , A61K9/5015 , A61K9/5089 , A61K47/02 , A01N25/30 , A01N47/30
摘要: Provided is a method for increasing the solubility of a poorly-soluble substance used in pharmaceutical products, veterinary pharmaceutical products, quasi-drugs, cosmetic products, food products, agricultural chemicals, and the like, without using large amounts of additives. This is a method for improving aqueous solubility, which comprises coating the surface of the particle of a poorly-soluble substance used in pharmaceutical products, veterinary pharmaceutical products, quasi-drugs, cosmetic products, food products, agricultural chemicals, and the like, with microparticles of a calcium compound such as calcium phosphate or calcium carbonate.
摘要翻译: 本发明提供了在不使用大量添加剂的情况下,增加药物,兽药,准药,化妆品,食品,农药等中使用的难溶性物质的溶解性的方法。 这是提高水溶性的方法,其包括将用于药物产品,兽药,准药,化妆品,食品,农药等的难溶性物质的颗粒表面涂覆在其中, 钙化合物如磷酸钙或碳酸钙的微粒。
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公开(公告)号:US20130172634A1
公开(公告)日:2013-07-04
申请号:US13822047
申请日:2011-09-14
申请人: Tetsuya Yoshioka , Takashi Tsuchida , Jun Kubo , Shuji Sakuma
发明人: Tetsuya Yoshioka , Takashi Tsuchida , Jun Kubo , Shuji Sakuma
IPC分类号: C07C29/34
CPC分类号: C07C29/34 , B01J21/10 , B01J23/007 , B01J27/18 , B01J29/082 , B01J37/03 , C07C31/12 , C07C31/10 , C07C31/125
摘要: A method for increasing the yield of alcohols by a Guerbet reaction in a gas phase and reducing production cost is provided. A method for producing alcohols by a Guerbet reaction, wherein the reaction is performed in a gas phase and at a total pressure of less than 1 atm and preferably from 0.01 to 0.5 atm, using one or more raw material alcohols.
摘要翻译: 提供了一种通过Guerbet反应在气相中提高醇的产率并降低生产成本的方法。 通过Guerbet反应制备醇的方法,其中使用一种或多种原料醇在气相和小于1atm,优选0.01至0.5atm的总压下进行反应。
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公开(公告)号:US5348577A
公开(公告)日:1994-09-20
申请号:US967067
申请日:1992-10-28
申请人: Kiminori Atsumi , Tomoki Saito , Masaaki Komori
发明人: Kiminori Atsumi , Tomoki Saito , Masaaki Komori
CPC分类号: A01N59/16
摘要: A calcium tertiary phosphate is used as a carrier, and the carrier is caused to carry silver and zinc. The result is an antibacterial ceramic exhibiting an ultra high degree of whiteness and suppressed discoloration. This material may be heat fired at a temperature above 960.degree. C. to obtain a further improvement.
摘要翻译: 使用磷酸三钙作为载体,并使载体携带银和锌。 结果是具有超高白度和抑制变色的抗菌陶瓷。 该材料可以在高于960℃的温度下进行热处理以获得进一步的改进。
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公开(公告)号:US4691718A
公开(公告)日:1987-09-08
申请号:US846069
申请日:1986-03-31
申请人: Shuji Sakuma , Hirotaka Fujinawa
发明人: Shuji Sakuma , Hirotaka Fujinawa
CPC分类号: A61N1/303
摘要: A toothbrush includes a bristle portion having implanted bristles and molded from an ion eluting-type ceramic, a conductor extending into the interior of the bristle portion, and a battery to which the conductor is connected. An electric current flows from the user's hand toward the surface of the teeth through the user's body as the teeth are brushed, thereby causing calcium of fluorine ion, which elutes from the ceramic constituting the bristle portion, to be deposited onto and to penetrate the teeth and dental pulpa while tartar is removed from the surface of the teeth by electronic decomposition.
摘要翻译: 牙刷包括具有植入的刷毛并由离子洗脱型陶瓷模制的刷毛部分,延伸到刷毛部分的内部的导体和连接导体的电池。 当刷牙时,电流从使用者的手朝着使用者身体的牙齿表面流动,从而从构成刷毛部分的陶瓷洗脱出的氟离子钙被沉积到牙齿上并穿过牙齿 和牙髓,而牙垢通过电子分解从牙齿表面除去。
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公开(公告)号:US11007125B2
公开(公告)日:2021-05-18
申请号:US15742747
申请日:2016-07-12
发明人: Tsutomu Ishizaki , Tadayoshi Arakawa , Kazushi Ota
IPC分类号: C09K3/00 , A61K6/838 , A61K6/17 , A61K6/20 , A61K6/78 , B05B1/30 , B05D1/12 , C04B35/626 , C01B25/32
摘要: In order to provide a film-forming powder using hydroxyapatite which is a main component of teeth, or hydroxyapatite in which a color tone adjuster is blended, the powder being used in a jet-device for forming a film on a surface of a tooth by spraying the powder on the tooth, and being suitable for forming a film having a high hardness and extremely low solubility in acid in a short period of time, and suitable for forming a film of a powder conforming to the color tone of a tooth in a short period of time; a hydroxyapatite powder calcined in an inert gas atmosphere at 600 to 1350° C., a powder obtained by applying to the hydroxyapatite powder calcined at 600 to 1350° C. plasma irradiation, or plasma irradiation and mechanical energy, and additionally a film-forming powders obtained by blending color tone adjusters into these hydroxyapatite powders are produced.
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公开(公告)号:US10039698B2
公开(公告)日:2018-08-07
申请号:US15510648
申请日:2016-01-14
发明人: Takayuki Itakura , Rimiko Takikawa , Mariko Obuki , Rie Takamatsu
摘要: An object of the present invention is to provide a tooth-cleaning composition having a high remineralizing effect on demineralized dental enamel. The tooth-cleaning composition contains a wax and a calcium phosphate, wherein a content of the calcium phosphate is 0.001 to 33% by mass.
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公开(公告)号:US08232433B2
公开(公告)日:2012-07-31
申请号:US12602885
申请日:2009-08-17
申请人: Ayumu Onda , Shuhei Ogo , Kazumichi Yanagisawa
发明人: Ayumu Onda , Shuhei Ogo , Kazumichi Yanagisawa
CPC分类号: C07C29/34 , B01J27/1806 , C07C31/12
摘要: The present invention is intended to provide a catalyst which is for synthesizing butanol from ethanol at a high selectivity and which comprises strontium phosphate apatite having the Sr/P atomic ratio of 1.5-2.0, and the synthesis method.
摘要翻译: 本发明旨在提供一种用于以高选择性从乙醇合成丁醇并且包含Sr / P原子比为1.5-2.0的磷酸锶磷灰石的催化剂及其合成方法。
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10.
公开(公告)号:US07250453B2
公开(公告)日:2007-07-31
申请号:US10492352
申请日:2002-10-10
申请人: Shuji Sakuma , Tomoki Saito , Yuki Sasaki , Yasuo Matsumura , Etsuo Tominaga , Takayoshi Aoki
发明人: Shuji Sakuma , Tomoki Saito , Yuki Sasaki , Yasuo Matsumura , Etsuo Tominaga , Takayoshi Aoki
IPC分类号: C09D5/16
CPC分类号: C08K9/02 , A01N59/16 , A01N59/20 , D01F1/103 , A01N2300/00
摘要: Anti-bacterial composite particles which comprise a polymer base material comprising a thermal melting polymer, such as a polyolefine, exhibiting good dispersibility in a basic material resin and having a lower molecular weight or a lower softening point than that of the basic material resin, and inorganic fine particles comprising a metal having anti-bacterial activity carried thereon. An antibacterial resin composition can be prepared by melting and kneading a synthetic resin composition as the basic material resin together with the anti-bacterial composite particles and forming by known molding methods such as extrusion molding and injection molding, and can be used for producing various synthetic resin moldings which have an inorganic anti-bacterial agent uniformly dispersed in a synthetic resin composition and thus exhibits good anti-bacterial effect.
摘要翻译: 包含聚合物基材的抗细菌复合颗粒包括在碱性材料树脂中表现出良好分散性并且具有比基本材料树脂低的分子量或更低的软化点的热熔性聚合物如聚烯烃,以及 包含其上承载有抗菌活性的金属的无机细颗粒。 可以通过将合成树脂组合物作为基础材料树脂与抗菌复合颗粒一起熔融捏合并通过已知的模塑方法如挤压成型和注塑成型来制备抗菌树脂组合物,并且可以用于生产各种合成 具有均匀分散在合成树脂组合物中的无机抗菌剂并因此表现出良好的抗菌作用的树脂模制品。
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