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公开(公告)号：US20240342395A1
公开(公告)日：2024-10-17
申请号：US18638893
申请日：2024-04-18
发明人： Stephen H. Diaz , Alan E. Shluzas
CPC分类号： A61M5/36 , A61F9/0017 , A61M5/3135 , A61M5/3137 , A61M5/3146 , A61M5/31505 , A61M5/31511 , A61M5/31515 , A61M5/31531 , A61M5/3157 , A61M5/347 , A61M2005/3143 , A61M2205/0216 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/584
摘要： A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member. The plunger member includes a rotatable member configured to insert the stopper member distally in the syringe interior relative to the syringe body with rotation of the rotatable member. The plunger member further includes a proximal portion proximal of the rotatable member configured to be moved distally to also insert the stopper member distally in the syringe interior relative to the syringe body to eject about microliters of fluid from the syringe interior.
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公开(公告)号：US20240024587A1
公开(公告)日：2024-01-25
申请号：US18447435
申请日：2023-08-10
发明人： Gary Steese-Bradley , Stephen H. Diaz , Alan E. Shluzas , John F. Shanley , Jeff Tillack , Dan Thayer , John Merhige
CPC分类号： A61M5/3221 , A61M5/178 , A61M5/2448 , A61M5/2066 , A61M5/284 , A61M5/28 , A61M5/3234 , A61M5/31501 , A61M5/31511 , A61M5/3202 , A61M5/322 , A61M5/3137 , A61M5/3148 , A61M5/31513 , A61M2005/3231 , A61M2005/3223 , A61M2005/3241 , A61M5/3232 , A61M2005/323 , A61J1/2006
摘要： A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.
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公开(公告)号：US11844937B2
公开(公告)日：2023-12-19
申请号：US16824625
申请日：2020-03-19
发明人： Mina M. Leung , Jeff Tillack , Stephen H. Diaz
CPC分类号： A61M5/344 , A61M5/3202 , A61M5/3293 , A61M5/347 , A61M5/46 , A61M2005/312
摘要： An injection system includes a body member having a body connection member at a distal end thereof. The system also includes a needle hub assembly coupled to the distal end of the injection system body. The needle hub assembly includes a needle hub coupled to the body connection member, a needle coupled to the needle hub, and a spacer removably coupled to the needle hub. The spacer reduces an exposed length of the needle.
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公开(公告)号：US20230248913A1
公开(公告)日：2023-08-10
申请号：US18098295
申请日：2023-01-18
发明人： Stephen H. Diaz , Jeff Tillack , Alan E. Shluzas
CPC分类号： A61M5/19 , A61M5/34 , A61M5/31515 , A61M2005/3128
摘要： An injection system includes an injection system body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the injection system body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the injection system body. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a valve forming an openable barrier between the distal needle interface and at least a portion of the distal drug chamber. The valve is configured to allow flow from the portion of the distal drug chamber to the distal needle interface with increased pressure in the distal drug chamber.
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公开(公告)号：US11712525B2
公开(公告)日：2023-08-01
申请号：US16908531
申请日：2020-06-22
发明人： Stephen H. Diaz , Gary Steese-Bradley , Alan E. Shluzas , Conor Edward Shanley , Mina M. Leung , Jeff Tillack
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/31511 , A61J1/201
摘要： An injection system includes a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the syringe body, forming respective proximal and distal drug chambers. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body. Moreover, the system includes a fluid conveying assembly including a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers, a distal exit tube, and a transfer member disposed at least partially around a portion of the penetrating member and defining a fluid passage. A distal end of the penetrating member is disposed in the distal exit tube.
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公开(公告)号：US20230147715A1
公开(公告)日：2023-05-11
申请号：US18091959
申请日：2022-12-30
发明人： Jeff Tillack , Alan E. Shluzas , Stephen H. Diaz , Gary Steese-Bradley , John Merhige , Conor Edward Shanley , Mina M. Leung
CPC分类号： A61M5/2448 , A61M5/2066 , A61M5/284 , A61M2005/1787
摘要： A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.
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公开(公告)号：US11541179B2
公开(公告)日：2023-01-03
申请号：US16798188
申请日：2020-02-21
发明人： Jeff Tillack , Alan E. Shluzas , Stephen H. Diaz , Gary Steese-Bradley , John Merhige , Conor Edward Shanley , Mina M. Leung
摘要： A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.
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公开(公告)号：US20220387731A1
公开(公告)日：2022-12-08
申请号：US17888133
申请日：2022-08-15
发明人： Stephen H. Diaz , Alan E. Shluzas
摘要： In one embodiment, a system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a stopper member disposed in the syringe interior. Moreover, the system includes a plunger member coupled to the stopper member. In addition, the system includes a finger flange removably coupled to the syringe flange, the finger flange including a proximally directed screw. The system also includes a rotatable member disposed on the proximally directed screw, the rotatable member defining a rotatable member opening through which the plunger member is disposed and having an elastic latch disposed adjacent the rotatable member opening.
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公开(公告)号：US20220134021A1
公开(公告)日：2022-05-05
申请号：US17574279
申请日：2022-01-12
摘要： A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a finger flange coupled to the syringe flange. Moreover, the system includes a stopper member disposed in the syringe interior. In addition, the system includes a plunger ratchet member coupled to the stopper member. The system also includes a plunger tube disposed coaxially around at least a portion of the plunger ratchet member and operatively coupled thereto.
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公开(公告)号：US10912895B2
公开(公告)日：2021-02-09
申请号：US15985354
申请日：2018-05-21
发明人： Stephen H. Diaz , Alan E. Shluzas , John F. Shanley , Jeff Tillack , John Merhige , Frank Litvack , Dan Thayer
摘要： A system for measuring injection of a liquid medicine includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member and configured to be manipulated to insert the stopper member distally in the syringe interior relative to the syringe body. Moreover, the system includes a needle coupled to the syringe body at the distal end thereof. In addition, the system includes a sensor flange removably coupled to a syringe body. The sensor flange includes a sensor to measure an injection characteristic and a processor to analyze the injection characteristic to determine an occurrence of an injection event.
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