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公开(公告)号：US20170107239A1
公开(公告)日：2017-04-20
申请号：US15333049
申请日：2016-10-24
发明人： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
摘要： Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20160304539A1
公开(公告)日：2016-10-20
申请号：US15194433
申请日：2016-06-27
发明人： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT , Randy W. JACKSON
CPC分类号： C07F5/025 , A61K31/407 , A61K31/496 , A61K31/546 , A61K31/69 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
摘要： Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US09403850B2
公开(公告)日：2016-08-02
申请号：US14759853
申请日：2014-01-10
发明人： Christopher J. Burns , Denis Daigle , Bin Liu , Daniel McGarry , Daniel C. Pevear , Robert E. Lee Trout , Randy W. Jackson
IPC分类号： A61K31/407 , C07F5/02 , A61K31/69 , A61K45/06 , A61K31/496 , A61K31/546
CPC分类号： C07F5/025 , A61K31/407 , A61K31/496 , A61K31/546 , A61K31/69 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
摘要： Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20150361106A1
公开(公告)日：2015-12-17
申请号：US14737323
申请日：2015-06-11
发明人： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
摘要： Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US09040504B2
公开(公告)日：2015-05-26
申请号：US14152916
申请日：2014-01-10
发明人： Christopher J. Burns , Denis Daigle , Bin Liu , Daniel McGarry , Daniel C. Pevear , Robert E. Lee Trout , Randy W. Jackson
CPC分类号： C07F5/025 , A61K31/407 , A61K31/496 , A61K31/546 , A61K31/69 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
摘要： Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
摘要翻译： 本文描述了调节β-内酰胺酶活性的化合物和组合物。 在一些实施方案中，本文所述的化合物抑制β-内酰胺酶。 在某些实施方案中，本文所述的化合物可用于治疗细菌感染。
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公开(公告)号：US08912169B2
公开(公告)日：2014-12-16
申请号：US14099633
申请日：2013-12-06
发明人： Christopher J. Burns , Denis Daigle , Bin Liu , Daniel McGarry , Daniel C. Pevear , Robert E. Lee Trout
CPC分类号： C07F5/025 , A61K9/0019 , A61K9/0053 , A61K31/69 , A61K45/06 , C07F5/027 , C07F5/04
摘要： Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
摘要翻译： 本文描述了调节β-内酰胺酶活性的化合物和组合物。 在一些实施方案中，本文所述的化合物抑制β-内酰胺酶。 在某些实施方案中，本文所述的化合物可用于治疗细菌感染。
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