公开(公告)号：US08180128B2

公开(公告)日：2012-05-15

申请号：US12219613

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

发明人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

IPC分类号： G01R33/56 ,  G01R33/54

CPC分类号： A61B6/032 ,  A61B5/11 ,  A61B5/7285 ,  A61B6/037 ,  A61B6/541 ,  A61B8/00 ,  A61B8/4416 ,  G06F19/00

摘要： A method is disclosed for recording measured data of a patient while taking account of movement operations by way of a medical device that is designed both for recording movement-related measured data, in particular measured data of high temporal resolution and/or measured data that can be interpolated with regard to movement operations, with the aid of an imaging method and/or by means of at least one sensor element, and also for recording nuclear medicine measured data, in particular of lower temporal resolution. In at least one embodiment, the method includes recording nuclear medicine measured data with the aid of the medical device; simultaneously recording movement-related measured data with the aid of the medical device; determining at least one item of movement information relating to at least one movement operation of the patient and/or in the body of the patient by evaluating at least a portion of the recorded measured data of high temporal resolution on the part of a computing device of the medical device; and adapting at least one item of attenuation correction information available for the computing device and serving for reconstructing the nuclear medicine measured data, doing so as a function of the at least one determined item of movement information.

摘要翻译： 公开了一种用于记录患者的测量数据的方法，同时考虑到通过设计用于记录运动相关测量数据的医疗设备，特别是高时间分辨率的测量数据和/或可测量数据的测量数据， 借助于成像方法和/或通过至少一个传感器元件，以及用于记录核医学测量数据，特别是用于记录较低时间分辨率的内插关于移动操作。 在至少一个实施例中，该方法包括借助医疗装置记录核医学测量数据; 借助医疗设备同时记录运动相关测量数据; 通过在计算设备的一部分上评估所记录的高时间分辨率的测量数据的至少一部分来确定与患者的至少一个移动操作和/或患者身体有关的至少一个移动信息项 医疗器械; 以及修改可用于所述计算设备的至少一项衰减校正信息，并且用于重构所述核医学测量数据，作为所述至少一个确定的运动信息项的函数。

公开(公告)号：US07960971B2

公开(公告)日：2011-06-14

申请号：US12358546

申请日：2009-01-23

申请人： Thorsten Feiweier

发明人： Thorsten Feiweier

IPC分类号： G01V3/00

CPC分类号： G01R33/3415 ,  G01R33/246 ,  G01R33/5612 ,  G01R33/5659 ,  G01R33/583

摘要： In a method for determination of flip angle distributions for various antenna transmission configurations in a magnetic resonance system, magnetic resonance measurements are implemented with the various transmission configurations, with the reception configuration being identical for all implemented magnetic resonance measurements, and all magnetic resonance measurements for the various transmission configurations are implemented with a specific pulse sequence. This pulse sequence is selected such that the total function that describes the dependency of the image signal at a specific location on the flip angle achieved at this location with the radiated radio-frequency field, as well as on further MR-relevant parameters, can be factored into a first sub-function that describes the dependency of the image signal on the achieved flip angle and a second sub-function (Tb) that describes the dependency of the image signal on the further MR-relevant parameters, and such that the functional dependency of the image signal on the achieved flip angle is known. The absolute flip angle distribution is measured for a reference transmission configuration, and the flip angle distributions of the other transmission configurations are then respectively determined on the basis of the absolute flip angle distribution of the reference transmission configuration and on the basis of the ratio of the spatially-dependent image signals of the magnetic resonance measurements of the respective transmission configuration to the corresponding spatially-dependent image signals of the magnetic resonance measurement of the reference transmission configuration.

摘要翻译： 在用于确定磁共振系统中的各种天线传输配置的翻转角分布的方法中，使用各种传输配置来实现磁共振测量，其中接收配置对于所有实现的磁共振测量是相同的，并且对于 以特定脉冲序列实现各种传输配置。 选择该脉冲序列，使得描述在具有辐射射频场的该位置处实现的翻转角上的特定位置处的图像信号的依赖性的总函数以及另外的MR相关参数可以是 考虑到描述图像信号对实现的翻转角的依赖性的第一子功能和描述图像信号对另外的MR相关参数的依赖性的第二子功能（Tb），并且使得功能 已知图像信号对实现的翻转角的依赖性。 对于参考传输配置来测量绝对翻转角分布，然后分别基于参考传输配置的绝对翻转角分布来确定其他传输配置的翻转角分布，并且基于 相应的传输配置的磁共振测量的空间相关图像信号与参考传输配置的磁共振测量的对应的空间相关图像信号。

公开(公告)号：US20110043204A1

公开(公告)日：2011-02-24

申请号：US12859461

申请日：2010-08-19

申请人： Wolfgang Bielmeier ,  Gerhard Brinker ,  Swen Campagna ,  Thorsten Feiweier ,  Bernd Kuehn ,  Mathias Nittka ,  Carsten Prinz ,  Thorsten Speckner

发明人： Wolfgang Bielmeier ,  Gerhard Brinker ,  Swen Campagna ,  Thorsten Feiweier ,  Bernd Kuehn ,  Mathias Nittka ,  Carsten Prinz ,  Thorsten Speckner

IPC分类号： G01R33/44

CPC分类号： G01R33/546 ,  G01R33/543

摘要： In a magnetic resonance system according to a measurement protocol defined in advance and comprising multiple acquisition parameters, wherein given a non-compliance with at least one limit value (which is automatically established before the beginning of a subject-specific measurement data acquisition)—in particular a SAR limit value and/or a magneto-stimulation limit value and/or a hardware limit value—by the measurement protocol, an adaptation of at least one acquisition parameter ensues using at least one (in particular user-defined) protocol-specific rule for compliance with the limit value, and the measurement data acquisition ensues automatically according to the adapted acquisition parameters.

摘要翻译： 在根据预先定义并包括多个采集参数的测量协议的磁共振系统中，其中给定不符合至少一个限制值（其在对象特异性测量数据获取开始之前自动建立） - 在 特别是SAR限制值和/或磁刺激极限值和/或硬件限制值 - 通过测量协议，使用至少一个（特别是用户定义的）协议特定的随机序列来调整至少一个采集参数 根据适应的采集参数自动进行测量数据采集。

公开(公告)号：US20100171498A1

公开(公告)日：2010-07-08

申请号：US12650757

申请日：2009-12-31

申请人： Karin Auslender ,  Thorsten Feiweier ,  Stefan Huwer

发明人： Karin Auslender ,  Thorsten Feiweier ,  Stefan Huwer

IPC分类号： G01R33/48 ,  G06K9/00

CPC分类号： G01R33/56341 ,  A61B5/055 ,  A61B5/7207 ,  G01R33/56518

摘要： In a method and magnetic resonance (MR) system for correction of image distortions that occur in acquisitions of diffusion-weighted MR images of an examination subject a first adjustment measurement with a first diffusion weighting is implemented, a second adjustment measurement with a second diffusion weighting is implemented and correction parameters to de-skew diffusion-weighted MR images are automatically calculated in a computer on the basis of the two adjustment measurements. One of the two adjustment measurements is implemented with a predetermined diffusion weighting in three orthogonal diffusion directions, and correction parameters are determined for the three orthogonal diffusion directions.

摘要翻译： 在用于校正在检查对象的扩散加权MR图像的采集中发生的图像失真的方法和磁共振（MR）系统中，实现具有第一扩散加权的第一调整测量，具有第二扩散加权的第二调整测量 并且基于两个调整测量在计算机中自动计算用于去偏斜扩散加权的MR图像的校正参数。 两个调整测量中的一个在三个正交扩散方向上以预定的扩散加权来实现，并且为三个正交扩散方向确定校正参数。

公开(公告)号：US07634303B2

公开(公告)日：2009-12-15

申请号：US11768531

申请日：2007-06-26

申请人： Yvonne Candidus ,  Thorsten Feiweier ,  Wilhelm Horger ,  Jürgen Huber ,  Razvan Lazar ,  Melanie Schmitt ,  Lothar Schön

发明人： Yvonne Candidus ,  Thorsten Feiweier ,  Wilhelm Horger ,  Jürgen Huber ,  Razvan Lazar ,  Melanie Schmitt ,  Lothar Schön

IPC分类号： A61B5/05 ,  G01V3/00 ,  B23P17/04

CPC分类号： G01R33/28 ,  G01R33/34 ,  G01R33/5659 ,  Y10T29/49

摘要： A dielectric element is formed of a dielectric material exhibiting a magnetic resonance relaxation time, with a relaxation agent incorporated in the dielectric material that reduces the relaxation time of the dielectric material. The dielectric element is adapted for placement on a subject while magnetic resonance data are acquired from the subject, and locally influences the B1 field distribution in the subject during the acquisition of magnetic resonance data.

摘要翻译： 电介质元件由表现出磁共振弛豫时间的电介质材料形成，并且电介质材料中包含减轻电介质材料弛豫时间的松弛剂。 介电元件适于放置在被摄体上，同时从受检者获取磁共振数据，并且在获取磁共振数据期间局部影响对象中的B1场分布。

公开(公告)号：US07603157B2

公开(公告)日：2009-10-13

申请号：US10921583

申请日：2004-08-19

申请人： Thorsten Feiweier ,  Franz Hebrank

发明人： Thorsten Feiweier ,  Franz Hebrank

IPC分类号： A61B5/05

CPC分类号： G01R33/5659

摘要： In a method and magnetic resonance apparatus for compensation of contrast inhomogeneities in magnetic resonance images caused by spatial distributions of the radio frequency field associated with the radio frequency pulses that are emitted in order to acquire magnetic resonance (MR) data, multiple individual MR images of a particular region of a subject are recorded with different radio frequency pulse sequences leading to different flip angles. A common contrast-homogenized image for the affected region then is generated based on the different individual images, so that within the contrast-homogenized image, intensity variations due to a distribution of the flip angle are smaller than in the individual images, at least in some areas.

摘要翻译： 在一种方法和磁共振装置中，用于补偿与为了获得磁共振（MR）数据而发射的射频脉冲相关联的射频场的空间分布引起的磁共振图像中的对比度不均匀性， 用不同的射频脉冲序列记录被摄体的特定区域，导致不同的翻转角度。 然后基于不同的单独图像生成受影响区域的常见对比均匀化图像，使得在对比均匀化图像内，由于翻转角分布引起的强度变化小于各个图像中的强度变化，至少在 一些地区。

公开(公告)号：US20090048507A1

公开(公告)日：2009-02-19

申请号：US12222210

申请日：2008-08-05

申请人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

发明人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

IPC分类号： A61B5/055 ,  A61B5/0476 ,  G01V3/00 ,  A61B6/00

CPC分类号： A61B6/037 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/4094 ,  A61B6/032 ,  A61B6/501 ,  A61B6/5247 ,  G06T7/30

摘要： A method and an apparatus for imaging functional and electrical activities of the brain are disclosed. In order to allow improved relative positional determination of the epileptogenic focus with reference to the EEG electrodes, a positron emission tomography measurement using at least one radiation detector, and a magnetic resonance imaging measurement using at least one coil for generating a basic magnetic field, at least one gradient coil and a radio-frequency antenna device are undertaken in at least one embodiment. In addition, in at least one embodiment an electroencephalography measurement using a plurality of electrodes for acquiring spatial and temporal changes of the electrical activities of the brain and a computed tomography measurement using at least one x-ray source and at least one x-ray detector are carried out. By way of an evaluation apparatus in at least one embodiment, a spatial correlation between the computed tomography measurement and the magnetic resonance imaging measurement is undertaken, so as to result in registration between the electroencephalography measurement and the positron emission tomography measurement.

摘要翻译： 公开了一种用于成像大脑的功能和电活动的方法和装置。 为了允许参考EEG电极改进癫痫发生焦点的相对位置确定，使用至少一个辐射检测器的正电子发射断层摄影测量和使用至少一个线圈产生基本磁场的磁共振成像测量，在 至少一个实施例中进行至少一个梯度线圈和射频天线装置。 另外，在至少一个实施例中，使用多个电极获取脑的电活动的空间和时间变化以及使用至少一个X射线源和至少一个X射线检测器的计算机断层摄影测量的脑电图测量 被执行。 通过至少一个实施例中的评估装置，进行计算机断层摄影测量和磁共振成像测量之间的空间相关性，以便导致脑电图测量与正电子发射断层摄影测量之间的对准。

公开(公告)号：US20090037130A1

公开(公告)日：2009-02-05

申请号：US12219610

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

发明人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

IPC分类号： G01R35/00

CPC分类号： A61B6/032 ,  A61B5/11 ,  A61B5/7285 ,  A61B6/037 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/00 ,  A61B8/4416 ,  A61B90/36 ,  A61B2090/364 ,  G06F19/00

摘要： A method is disclosed for recording measured data from a patient by taking movements into account by use of a medical device designed both for recording motion-related measured data, in particular measured data with a high temporal resolution and/or measured data which can be interpolated with regard to movements, using an imaging method and/or by use of at least one sensor element and for recording nuclear medicine measured data, in particular with a relatively low temporal resolution. In at least one embodiment, the method includes recording nuclear medicine measured data by use of the medical device; simultaneously recording motion-related measured data by use of the medical device; determining at least one motion information item relating to at least one movement of the patient and/or at least one movement inside the body of the patient during the ongoing measured data recording by evaluating at least a portion of the previously recorded motion-related measured data by use of a computational device of the medical device; and carrying out motion correction for at least a portion of the nuclear medicine measured data in real-time by use of the computational device in parallel with recording the measured data depending on the at least one determined motion information item.

摘要翻译： 公开了一种用于通过使用设计用于记录运动相关测量数据的医疗装置，特别是具有高时间分辨率的测量数据和/或可被内插的测量数据来考虑来自患者的测量数据来记录测量数据的方法 关于运动，使用成像方法和/或通过使用至少一个传感器元件并且用于记录核医学测量数据，特别是具有相对低的时间分辨率。 在至少一个实施例中，该方法包括使用医疗装置记录核医学测量数据; 通过使用医疗装置同时记录运动相关测量数据; 在正在进行的测量数据记录期间，通过评估先前记录的运动相关测量数据的至少一部分来确定与患者的至少一个运动和/或患者体内的至少一个运动相关的至少一个运动信息项 通过使用医疗装置的计算装置; 以及根据所述至少一个所确定的运动信息项，通过使用所述计算装置与记录所述测量数据并行地对所述核医学测量数据的至少一部分进行实时运动校正。

公开(公告)号：US20080290281A1

公开(公告)日：2008-11-27

申请号：US12153487

申请日：2008-05-20

申请人： Diana Martin ,  Thorsten Feiweier ,  Gunther Platsch ,  Kristin Schmiedehausen ,  Sebastian Schmidt ,  Michael Szimtenings

发明人： Diana Martin ,  Thorsten Feiweier ,  Gunther Platsch ,  Kristin Schmiedehausen ,  Sebastian Schmidt ,  Michael Szimtenings

IPC分类号： G01T1/164

CPC分类号： G01R33/481 ,  A61B6/501 ,  A61B6/5247 ,  A61B2090/364 ,  G01R33/4806

摘要： A method is disclosed for data acquisition and/or data evaluation during a functional brain examination with the aid of a combined magnetic resonance/PET unit. In at least one embodiment, functional image data of the brain are acquired in at least two activity states with the aid of both modalities. Further, magnetic resonance image data and PET image data are acquired within time windows determined by the activity states, the acquisition mode and/or the image data being synchronized as a function of a timing of stimulations determining the activity states.

摘要翻译： 公开了一种借助于组合磁共振/ PET单元在功能性脑部检查期间进行数据采集和/或数据评估的方法。 在至少一个实施例中，借助于两种模式在至少两个活动状态中获取大脑的功能图像数据。 此外，在由活动状态确定的时间窗内获取磁共振图像数据和PET图像数据，获取模式和/或图像数据作为确定活动状态的刺激的定时的函数被同步。

公开(公告)号：US20080061779A1

公开(公告)日：2008-03-13

申请号：US11851462

申请日：2007-09-07

申请人： Thorsten Feiweier

发明人： Thorsten Feiweier

IPC分类号： G01V3/00 ,  G06K9/00

CPC分类号： G01R33/561 ,  G01R33/4818 ,  G01R33/4824 ,  G01R33/56509

摘要： In a measurement sequence and apparatus for three-dimensional magnetic resonance imaging, in which an acquisition of measurement data ensues by scanning multiple lines in k-space; and the number of k-space lines is apportioned among a number of partial acquisitions so that scanning of associated k-space lines occurs in each partial acquisition, the k-space lines are associated with the partial acquisitions such that the association corresponds to the following association rule: (a) evaluation of each k-space line with an interval measurement that characterizes the interval of the respective k-space line relative to the k-space center, (b) arrangement of the k-space lines to be scanned in an order dependent on the interval measure, (c) grouping of the k-space lines arranged in order into a number of groups with a number of successive k-space lines being combined into a group, and (d) association of the k-space lines with the partial acquisitions by, for each group, the k-space lines combined into this group are apportioned to different partial acquisitions.

摘要翻译： 在用于三维磁共振成像的测量序列和装置中，其中通过扫描k空间中的多条线来进行测量数据的采集; 并且在多次部分获取中分配k空间线的数量，使得在每个部分采集中发生相关联的k空间线的扫描，所述k空间线与部分采集相关联，使得该关联对应于以下 关联规则：（a）用表征各个k空间线相对于k空间中心的间隔的间隔测量的每个k空间线的评估，（b）要扫描的k空间线的排列 依赖于间隔测量的顺序，（c）按顺序排列的k空间线组合成多个组，其中多个连续的k空间线被组合成一组，以及（d）k- 对于每个组，对组合到该组的k空间线进行部分采集的空间线被分配给不同的部分采集。