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71.发明授权公开(公告)号：US11580410B2
公开(公告)日：2023-02-14
申请号：US16964388
申请日：2019-01-24
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Hongming Shan , Wenxiang Cong
Abstract: A 3-D convolutional autoencoder for low-dose CT via transfer learning from a 2-D trained network is described, A machine learning method for low dose computed tomography (LDCT) image correction is provided. The method includes training, by a training circuitry, a neural network (NN) based, at least in part, on two-dimensional (2-D) training data. The 2-D training data includes a plurality of 2-D training image pairs. Each 2-D image pair includes one training input image and one corresponding target output image. The training includes adjusting at least one of a plurality of 2-D weights based, at least in part, on an objective function. The method further includes refining, by the training circuitry, the NN based, at least in part, on three-dimensional (3-D) training data. The 3-D training data includes a plurality of 3-D training image pairs. Each 3-D training image pair includes a plurality of adjacent 2-D training input images and at least one corresponding target output image. The refining includes adjusting at least one of a plurality of 3-D weights based, at least in part, on the plurality of 2-D weights and based, at least in part, on the objective function. The plurality of 2-D weights includes the at least one adjusted 2-D weight.
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公开(公告)号：US11266363B2
公开(公告)日：2022-03-08
申请号：US15999466
申请日：2017-02-17
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Wenxiang Cong
Abstract: Systems and methods for obtaining scattering images during computed tomography (CT) imaging are provided. Two gratings or grating layers can be disposed between the object to be imaged and the detector, and the gratings or grating layers can be arranged such that primary X-rays are blocked while scattered X-rays that are deflected as they pass through the object to be imaged reach the detector to generate the scattering image.
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公开(公告)号：US20210321961A1
公开(公告)日：2021-10-21
申请号：US17354286
申请日：2021-06-22
Applicant: Rensselaer Polytechnic Institute
Inventor： Daniel David Harrison , Ge Wang
Abstract: Systems and method for performing X-ray computed tomography (CT) that can improve spectral separation and decrease motion artifacts without increasing radiation dose are provided. The systems and method can be used with either a kVp-switching source or a single-kVp source. When used with a kVp-switching source, an absorption grating and a filter grating can be disposed between the X-ray source and the sample to be imaged. Relative motion of the filter and absorption gratings can by synchronized to the kVp switching frequency of the X-ray source. When used with a single-kVp source, a combination of absorption and filter gratings can be used and can be driven in an oscillation movement that is optimized for a single-kVp X-ray source. With a single-kVp source, the absorption grating can also be omitted and the filter grating can remain stationary.
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公开(公告)号：US20210149005A1
公开(公告)日：2021-05-20
申请号：US16768834
申请日：2018-12-07
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
IPC: G01R33/54 , G01R33/56 , G01R33/565 , G01R33/561
Abstract: A synergized pulsing-imaging network is described. A method of optimizing a magnetic resonance imaging (MRI) system includes optimizing, by a synergized pulsing-imaging network (SPIN) circuitry a pulse sequence based, at least in part, on a loss function associated with a reconstruction network. The method further includes optimizing, by the SPIN circuitry, the reconstruction network based, at least in part, on intermediate raw MRI data and based, at least in part, on a ground truth MRI image data. The intermediate raw MRI data is determined based, at least in part on the pulse sequence.
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公开(公告)号：US11006916B2
公开(公告)日：2021-05-18
申请号：US15452802
申请日：2017-03-08
Applicant: Pusan National University Industry-University Cooperation Foundation , RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Seungwook Lee , Ohsung Oh , Ge Wang
Abstract: Provided are an apparatus and method for K-edge based interior tomography image processing. The apparatus efficiently performs tomography image reconstruction by acquiring different material images using an energy-selective detector, such as a photon counting detector. The apparatus includes a projection image acquisition unit configured to inject a contrast agent into an object and acquire projection images using the energy-selective detector with respect to a K-edge of the material, a parameter initialization unit configured to initialize parameters needed for image reconfiguration, an ROI interior reconstruction unit configured to perform reconstruction for image reconfiguration until initial convergence is achieved in order to reconstruct an interior of a region of interest, a concentration and correction value calculation unit configured to calculate a concentration and a correction value (β) using a linear attenuation coefficient of the contrast agent and a linear attenuation coefficient of blood, which are known, in the acquired and reconstructed image.
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Patent Agency Ranking
公开(公告)号：US20210031055A1
公开(公告)日：2021-02-04
申请号：US17045978
申请日：2019-04-11
Applicant: Board of Regents of the University of Texas System , Rensselaer Polytechnic Institute Office Of Technology Transfer
Inventor： Steve Bin Jiang , Xun Jia , Ge Wang , Hak Choy , Nima Hassan-Rezaeian , Chenyang Shen
IPC: A61N5/10 , G01R33/3815 , A61B6/04 , A61B5/055 , G01R33/38 , G01R33/385 , G01R33/48 , G01R33/3875
Abstract: Various examples of methods, systems, apparatus and devices are provided for MRI adaptation for radiotherapy machines. In one example, a system for MRI-guided radiotherapy can include a mounting ring and superconducting magnets. The mounting ring can be installed on a gantry of a LINAC to rotate about an isocenter of the LINAC moving with the gantry. The first and second superconducting magnet can be positioned substantially parallel to each other at a separation distance with the centers substantially aligned. The first and second superconducting magnets can provide a main magnetic field within a region of interest located between the first and second superconducting magnets. The superconducting magnets can have an aperture positioned at the center of each magnet and can allow a radiotherapy beam emitting from the gantry head to pass through the apertures. In another example, superconducting magnets can be installed at opposite ends of a LINAC gantry.
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77.发明申请公开(公告)号：US20200380673A1
公开(公告)日：2020-12-03
申请号：US16621800
申请日：2018-06-18
Applicant: Rensselaer Polytechnic Institute
Inventor： Ge Wang , Mannudeep Kalra , Juergen Hahn , Uwe Kruger , Wenxiang Cong , Hongming Shan
Abstract: Computed tomography (CT) screening, diagnosis, or another image analysis tasks are performed using one or more networks and/or algorithms to either integrate complementary tomographic image reconstructions and radiomics or map tomographic raw data directly to diagnostic findings in the machine learning framework. One or more reconstruction networks are trained to reconstruct tomographic images from a training set of CT projection data. One or more radiomics networks are trained to extract features from the tomographic images and associated training diagnostic data. The networks/algorithms are integrated into an end-to-end network and trained. A set of tomographic data, e.g., CT projection data, and other relevant information from an individual is input to the end-to-end network, and a potential diagnosis for the individual based on the features extracted by the end-to-end network is produced. The systems and methods can be applied to CT projection data, MRI data, nuclear imaging data, ultrasound signals, optical data, other types of tomographic data, or combinations thereof.
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78.发明申请公开(公告)号：US20200273215A1
公开(公告)日：2020-08-27
申请号：US16647220
申请日：2018-09-26
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Wenxiang Cong
Abstract: A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening. An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.
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公开(公告)号：US10729397B2
公开(公告)日：2020-08-04
申请号：US15741026
申请日：2016-07-20
Inventor： Ge Wang , Wenxiang Cong , Zaifeng Shi , Shuo Pang
Abstract: Novel and advantageous systems and methods for performing X-ray imaging by extracting X-ray phase-shift and/or dark-field information through a detector that has built-in G2 functionality are provided. Grating translation can be replaced by an electrical operation in the detection procedure, thereby eliminating the need for the analyzer grating and the typical mechanical stepping process.
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公开(公告)号：US10539689B1
公开(公告)日：2020-01-21
申请号：US15545623
申请日：2016-01-25
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： Ge Wang , Wenxiang Cong , Zaifeng Shi
Abstract: Novel and advantageous methods and systems for performing computed tomography (CT) imaging are disclosed. Electrodes can be connected to appropriate surface sites of a detector element of a CT scanner to capture nearby electron-hole pairs generated by X-rays received on the detector element. This detection can be performed in current-integrating/energy-integrating mode.
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