公开(公告)号：US07151301B2

公开(公告)日：2006-12-19

申请号：US11057642

申请日：2005-02-14

申请人： Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

发明人： Kyu-tae Yoo ,  Geun-bae Lim ,  Joon-ho Kim ,  Kak Namkoong

IPC分类号： H01L29/76

CPC分类号： G01N27/4145

摘要： There is provided a biomolecule FET enhancing a sensitivity. The biomolecule FET includes a substrate, first and second impurity regions formed on both sides of the substrate, and doped with impurities of a polarity opposite to that of the substrate, a gate formed on the substrate and being in contact with the first and second impurity regions, and a probe biomolecule attached to the gate. A region of the gate adjacent to the first impurity region is wider than a region thereof adjacent to the second impurity region. A density of the probe biomolecule attached to the surface of the gate is increased, and when detecting a level of hybridization of the probe biomolecule and the target biomolecule, its sensitivity is improved.

摘要翻译： 提供了提高灵敏度的生物分子FET。 生物分子FET包括基板，形成在基板两侧的第一和第二杂质区，并且掺杂极性与基板极性相反的杂质;形成在基板上并与第一和第二杂质接触的栅极 区域，以及连接到门的探针生物分子。 与第一杂质区相邻的栅极的区域比与第二杂质区相邻的区域宽。 附着在栅极表面的探针生物分子的密度增加，并且当检测到探针生物分子和靶生物分子的杂交水平时，其灵敏度得到改善。

公开(公告)号：US20060185584A1

公开(公告)日：2006-08-24

申请号：US11341033

申请日：2006-01-27

申请人： Su-hyeon Kim ,  Jun-hong Min ,  Kak Namkoong

发明人： Su-hyeon Kim ,  Jun-hong Min ,  Kak Namkoong

IPC分类号： C30B11/00

CPC分类号： B01L3/50273 ,  B01L3/502746 ,  B01L2200/0621 ,  B01L2300/0816 ,  B01L2400/0409 ,  Y10T117/10

摘要： Provided are a microfluidic chip and a microfluidic manipulating apparatus including the same. The microfluidic chip includes at least one microfluidic manipulating unit formed in a substrate. The microfluidic manipulating unit includes: a plurality of microchannels formed in the substrate; an inlet formed at a first end of the microchannel and exposed through the substrate; a trap formed at the microchannel; a chamber connected to a second end of the microchannel; and an outlet connected to the chamber and exposed through the substrate.

摘要翻译： 提供了一种微流控芯片和包括该微流控芯片的微流控操纵装置。 微流体芯片包括形成在基板中的至少一个微流体操纵单元。 微流体操纵单元包括：形成在基板中的多个微通道; 入口，其形成在所述微通道的第一端处并暴露于所述基底; 在微通道处形成的陷阱; 连接到所述微通道的第二端的室; 以及连接到室并通过基板暴露的出口。