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    Quaternary ammonium polyol salts as anti-aging actives in personal care compositions
    55.
    发明授权
    Quaternary ammonium polyol salts as anti-aging actives in personal care compositions 有权
    季铵多元醇盐作为个人护理组合物中的抗衰老活性物质

    公开(公告)号：US07176172B2

    公开(公告)日：2007-02-13

    申请号：US10992405

    申请日：2004-11-18

    Applicant: Clive Roderick Harding ,  Bijan Harichian

    Inventor： Clive Roderick Harding ,  Bijan Harichian

    IPC: C11D1/62

    CPC classification number: A61Q19/08 ,  A61K8/416 ,  A61K8/60 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q19/10

    Abstract: A personal care product is provided which includes a package filed with a personal care composition and instructions printed on or associated with the package indicating topical use of the composition on skin for purposes of controlling the signs of aging. The composition includes a quaternary ammonium compound selected from (a) salts of hydroxypropyltri(C1–C3 alkyl)ammonium mono-substituted mono-saccharide; (b) salts of hydroxypropyltri(C1–C3 alkyl)ammonium mono-substituted polyols, the salts having a cation of an average molecular weight no higher than about 450 and the salt having a Tg no higher than about 10° C.; (c) dihydroxypropyltri(C1–C3 alkyl)ammonium salts; (d) chlorohydroxypropyltri(C1–C3 alkyl)ammonium salts; and (e) mixtures thereof.

    Abstract translation: 提供个人护理产品，其包括提供有个人护理组合物的包装，以及印刷在包装上或与包装有关的指令，其指示组合物在皮肤上局部使用以控制老化迹象。 该组合物包括选自（a）羟丙基三（C 1 -C 3） - 亚烷基）铵单取代的单糖的盐的季铵化合物; （b）羟丙基三（C 1 -C 3 -C 3烷基）铵单取代多元醇的盐，所述盐具有平均分子量不高于约450的阳离子，和 所述盐具有不高于约10℃的T <！ - SIPO

    Novel resorcinol derivatives for skin
    56.
    发明申请
    Novel resorcinol derivatives for skin 审中-公开
    用于皮肤的新型间苯二酚衍生物

    公开(公告)号：US20060210498A1

    公开(公告)日：2006-09-21

    申请号：US11084601

    申请日：2005-03-18

    Applicant: Bijan Harichian ,  Jose Rosa

    Inventor： Bijan Harichian ,  Jose Rosa

    IPC: A61K8/34 ,  C07C39/12

    CPC classification number: C07C69/017 ,  C07C39/17 ,  C07C2601/14

    Abstract: New 4-substituted resorcinol derivatives of general formula I and/or B and process for synthesizing same, cosmetic compositions and methods of using same, particularly for skin lightening: Wherein X1 and/or X2 represents hydrogen (H), linear or branched, saturated or unsaturated C1-C12 alkyl, alkenyl, or acyl groups. Preferably, X1 and/or X2 represents hydrogen (H); linear or branched, saturated or unsaturated C1-C12 alkyl or acyl groups; R1 represents hydrogen (H), linear or branched, cyclic or acyclic, saturated or unsaturated C1-C12 alkyl, alkenyl, cycloalkyl, or cycloalkenyl group. Preferably, R1 represents hydrogen (H) or a C1 alkyl group (i.e, methyl group). More preferably, R1 represents hydrogen; n represents 0, 1. When n=0, the ring is a cyclopentyl with or without one heteroatom from O, N or S and/or with or without one double bond. When n=1, the ring is a cyclohexyl with or without one heteroatom from O, N or S and/or with or without one double bond; and m represents an integer between 1 and 6.

    Abstract translation: 新的通式I和/或B的4-取代间苯二酚衍生物及其合成方法，化妆品组合物及其使用方法，特别是皮肤增白剂：其中X 1和/或X 1， 2 H表示氢（H），直链或支链的饱和或不饱和的C 1 -C 12烷基，烯基或酰基。 优选地，X 1和/或X 2代表氢（H）; 直链或支链的饱和或不饱和的C 1 -C 12烷基或酰基; R 1表示氢（H），直链或支链，环状或非环状的饱和或不饱和的C 1 -C 12烷基，烯基，环烷基 ，或环烯基。 优选地，R 1表示氢（H）或C 1烷基（即甲基）。 更优选地，R 1表示氢; 当n = 0时，环是具有或不具有来自O，N或S的一个杂原子的环戊基和/或具有或不具有一个双键的环戊基。 当n = 1时，环是具有或不具有来自O，N或S的一个杂原子和/或具有或不具有一个双键的环己基; m表示1〜6的整数。

    Cosmetic compositions containing Sophora alopecuroides L. extracts
    57.
    发明申请
    Cosmetic compositions containing Sophora alopecuroides L. extracts 审中-公开
    含有苦参芍药提取物的化妆品组合物

    公开(公告)号：US20060110341A1

    公开(公告)日：2006-05-25

    申请号：US10997204

    申请日：2004-11-24

    Applicant: Bijan Harichian ,  Minliang Zou ,  Hongqiang Wang

    Inventor： Bijan Harichian ,  Minliang Zou ,  Hongqiang Wang

    IPC: A61K38/19 ,  A61K36/489 ,  A61K8/35

    CPC classification number: A61Q19/02 ,  A61K8/97 ,  A61K36/489 ,  A61K2300/00

    Abstract: Disclosed are extracts of Sophora alopecuroides L. as cosmetic skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle. Also disclosed are active ingredients in the extracts, including Alopecurone A, Alopecurone B, Sophoraflavone-G, Sophoraflavone-I, Sophoraflavone-K, and mixtures thereof. The inventive extracts, compositions and methods have effective skin lightening properties, may be easier to deliver to the skin and are available in nature.

    Abstract translation: 公开了作为化妆品皮肤增白剂的苦参芍药提取物，或与其它皮肤有益剂组合，并与化妆品载体一起使用。 还公开了提取物中的活性成分，包括Alopecurone A，Alopecurone B，Sophoraflavone-G，Sophoraflavone-I，Sophoraflavone-K及其混合物。 本发明的提取物，组合物和方法具有有效的皮肤发光特性，可以更容易地递送至皮肤并且在本质上可用。

    Skin lightening agents, compositions and methods
    58.
    发明授权
    Skin lightening agents, compositions and methods 有权
    护肤剂，组合物和方法

    公开(公告)号：US06852310B2

    公开(公告)日：2005-02-08

    申请号：US10227642

    申请日：2002-08-23

    Applicant: Bijan Harichian ,  Michael James Barratt ,  Carol Annette Bosko

    Inventor： Bijan Harichian ,  Michael James Barratt ,  Carol Annette Bosko

    IPC: A61K8/42 ,  A61Q19/02 ,  A61K7/42 ,  A61K7/00 ,  A61K7/44

    CPC classification number: A61Q19/02 ,  A61K8/42

    Abstract: Cosmetic methods of skin lightening using coumarin derivatives of formula I as skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle: Where each or both R1 and/or R2 represents hydrogen; linear or branched C1-C18 alkyl, alkenyl, cycloalkyl, cycloalkenyl, hydroxyalkyl, hydroxyalkenyl, acyl, cycloacyl, or alkoxy groups; Each or both R3 and/or R4, which may be connected by a single or double carbon-carbon bond (shown as a dotted line), represents hydrogen; linear or branched C1-C18 alkyl, alkenyl, alkoxy, cycloalkyl, or cycloalkenyl group; and Each or both R5 and/or R6 represents a hydrogen atom, OH, C1-C4 acyl group, C1-C4 alkyl group, O—CO—R7, O—COO—R8 group, mesyl group or tosyl group, where each or both R7 and/or R8 represents hydrogen; linear or branched C1-C18 alkyl, alkenyl, hydroxyalkyl, hydroxyalkenyl, acyl, cycloacyl, or alkoxy groups.

    Abstract translation: 使用式I的香豆素衍生物作为皮肤增白剂单独使用或与其它皮肤有益剂组合以及与化妆品载体一起使用的美白方法：其中R1和/或R2各自表示氢; 直链或支链C 1 -C 18烷基，烯基，环烷基，环烯基，羟基烷基，羟基烯基，酰基，环酰基或烷氧基;可以通过单或双碳 - 碳键连接的各个或两个R 3和/或R 4 作为虚线）表示氢; 直链或支链C 1 -C 18烷基，烯基，烷氧基，环烷基或环烯基; R 5和/或R 6中的每一个或两个表示氢原子，OH，C 1 -C 4酰基，C 1 -C 4烷基，O-CO-R 7，O-COO-R 8基，甲磺酰基或甲苯磺酰基， R7和/或R8表示氢; 直链或支链C 1 -C 18烷基，烯基，羟烷基，羟烯基，酰基，环酰基或烷氧基。

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