公开(公告)号：US20060164663A1

公开(公告)日：2006-07-27

申请号：US11261034

申请日：2005-10-28

Applicant: Ming Luo ,  Kaida Xiao ,  Changjun Li

Inventor： Ming Luo ,  Kaida Xiao ,  Changjun Li

IPC: H04N1/60

CPC classification number: G01J3/526 ,  G01J3/46 ,  G01J3/465

Abstract: A method, combination or apparatus for compensating for or predicting the shift in the human perception of colour which occurs when the colour is seen on a small surface area as compared with when it is seen extending over of large surface area. The compensation or prediction is performed by increasing (compensation) or decreasing (prediction) the lightness and chroma of the colour in a specified way. The invention allows choosers of colour to take account of the shifts when making their choice of colours and is useful in choosing colours for paints, plastics, textiles or illuminated surfaces.

Abstract translation: 与在大面积上延伸的情况相比，当在小的表面积上看到颜色时，补偿或预测人类对颜色的感知的偏移的方法，组合或装置。 通过以指定的方式增加（补偿）或减少（预测）颜色的亮度和色度来执行补偿或预测。 本发明允许选择颜色在选择颜色时考虑到变化，并且可用于选择油漆，塑料，纺织品或照明表面的颜色。

公开(公告)号：US06987003B1

公开(公告)日：2006-01-17

申请号：US09316048

申请日：1999-05-21

Applicant: Luc Desgroseillers ,  Andrew J. Mouland ,  Eric A. Cohen ,  Louise Wickham ,  Ming Luo ,  Thomas Duchaîne

Inventor： Luc Desgroseillers ,  Andrew J. Mouland ,  Eric A. Cohen ,  Louise Wickham ,  Ming Luo ,  Thomas Duchaîne

IPC: C12P21/06 ,  C07H21/02 ,  C12N15/00 ,  C12N5/00

CPC classification number: C12N9/1241 ,  A61K38/00 ,  C07K14/43545 ,  C07K14/47

Abstract: The present invention relates to mammalian staufen, a double-stranded RNA-binding protein involved in mRNA transport and localization. The invention further relates to the demonstration of the association of a RNA-binding protein with the rough endoplasmic reticulum (RER), implicating staufen and related proteins in the transport of RNA to its site of translation. Broadly, the invention therefore relates to transport and translation of RNA. More specifically, the present invention relates to human and mouse staufen proteins and to the modulation of transport of RNA to the RER by these proteins. The present invention also relates to isolated nucleic acid molecules encoding mammalian staufen, as well as vectors and host cells harboring same. In addition, the present invention relates to screening assays for identifying modulators of staufen activity and to the identification of mutants thereof which abrogate their interaction with RER. Furthermore, the present invention relates to the use of the double-stranded RNA binding activity of staufen as a means to target proteins into virions. The invention in addition relates to the incorporation of staufen into RNA viruses and the use of overexpression of staufen to significantly decrease the infectivity thereof. More particularly, the present invention relates to a novel and broad class of molecules which can be used as carriers to target molecules into virions of RNA viruses and to decrease infectivity of a wide variety of RNA viruses including retroviruses.

Abstract translation: 本发明涉及哺乳动物staufen，涉及mRNA转运和定位的双链RNA结合蛋白。 本发明还涉及RNA结合蛋白与粗糙内质网（RER）的关联的证明，其涉及在转运RNA到其翻译位点时涉及到的staufen和相关蛋白质。 因此，广义上，本发明涉及RNA的转运和翻译。 更具体地说，本发明涉及人和小鼠粪蛋白蛋白以及通过这些蛋白质将RNA转运至RER的调节。 本发明还涉及编码哺乳动物staufen的分离的核酸分子以及含有其的载体和宿主细胞。 此外，本发明涉及用于鉴定staufen活性的调节剂的筛选测定法和鉴定其消除其与RER的相互作用的突变体。 此外，本发明涉及使用staufen的双链RNA结合活性作为将蛋白质靶向病毒粒子的手段。 本发明另外涉及将staufen并入RNA病毒中，并且使用staufen的过表达显着降低其感染性。 更具体地说，本发明涉及一种新颖且广泛的分子，其可以用作载体以将分子靶向RNA病毒的病毒粒子并降低包括逆转录病毒在内的各种RNA病毒的感染性。

公开(公告)号：US20050018191A1

公开(公告)日：2005-01-27

申请号：US10491706

申请日：2002-10-04

Applicant: Ming Luo ,  Chuangjun Li ,  Guihua Cui

Inventor： Ming Luo ,  Chuangjun Li ,  Guihua Cui

IPC: G01J3/10 ,  G01J3/46 ,  G01N21/25 ,  G01J3/40

CPC classification number: G01J3/10 ,  G01J3/46

Abstract: An apparatus and method for measuring colours of an object includes an enclosure for receiving the object; illumination means for illuminating the object within the enclosure; a digital camera for capturing an image of the object; a computer connected to the digital camera, for processing information relating to the image of the object; and display means for displaying information relating to the image of the object. The enclosure may include means for mounting an object therein such that its position may be altered. These means may include a tiltable table for receiving the object, the tiltable table being controllable by the computer. the illumination means are preferably located within the enclosure, and may include diffusing means for providing a diffuse light throughout the enclosure. the illumination means may include a plurality of different light sources for providing respectively different illuminations for the object, one or more of the light sources may be adjustable to adjust the level of the illumination or the direction of the illumination. The light sources may be controllable by the computer.

Abstract translation: 用于测量物体颜色的装置和方法包括：用于接收物体的外壳; 照明装置，用于照明外壳内的物体; 用于捕获对象的图像的数字照相机; 连接到数字照相机的计算机，用于处理与对象的图像有关的信息; 以及显示装置，用于显示与对象的图像有关的信息。 外壳可以包括用于将物体安装在其中的装置，使得其位置可以改变。 这些装置可以包括用于接收物体的可倾斜台，可倾斜台由计算机控制。 照明装置优选地位于外壳内，并且可以包括用于在整个外壳中提供漫射光的漫射装置。 照明装置可以包括多个不同的光源，用于为物体分别提供不同的照明，一个或多个光源可以是可调节的，以调节照明的水平或照明的方向。 光源可以由计算机控制。