公开(公告)号：US07860288B2

公开(公告)日：2010-12-28

申请号：US11809276

申请日：2007-05-31

Applicant: Philipp Bernhardt ,  Estelle Camus ,  Martin Hoheisel ,  Thomas Redel

Inventor： Philipp Bernhardt ,  Estelle Camus ,  Martin Hoheisel ,  Thomas Redel

IPC: G06K9/00 ,  H05G1/70 ,  H05G1/10 ,  A61B5/05 ,  A61B5/02

CPC classification number: G01N23/04 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482 ,  A61B6/504 ,  A61B6/507 ,  G06T2207/30101

Abstract: A sequence of groups of projection images shows an object under examination comprising a vascular system and its environment. A computer determines a 2-dimensional evaluation image having a plurality of pixels based on combination images determined from the projection images of a group. The combination images have a plurality of pixels with pixel values. The sequence of the combination images shows the time characteristic of the distribution of a contrast medium in the object. The pixels of the evaluation image correspond to those of the projection images. The computer assigns each pixel, at least in a part area of the evaluation image, a type that is characteristic of whether the respective pixel corresponds to a vessel of the vascular system, a perfusion area or a background. It performs the assignment of the type on the basis of the time characteristic of the pixel values of the combination images.

Abstract translation: 一组投影图像的一系列显示一个被检查的物体，包括血管系统及其环境。 基于从组的投影图像确定的组合图像，计算机确定具有多个像素的二维评估图像。 组合图像具有多个具有像素值的像素。 组合图像的顺序示出了对象中造影剂的分布的时间特性。 评估图像的像素对应于投影图像的像素。 计算机至少在评估图像的一部分区域中分配每个像素，其特征在于各个像素是否对应于血管系统的血管，灌注区域或背景。 它根据组合图像的像素值的时间特性来执行类型的分配。

公开(公告)号：US20100246769A1

公开(公告)日：2010-09-30

申请号：US12566858

申请日：2009-09-25

Applicant: Christian David ,  Tilman Donath ,  Eckhard Hempel ,  Martin Hoheisel ,  Barbara Matthis ,  Franz Pfeiffer ,  Stefan Popescu

Inventor： Christian David ,  Tilman Donath ,  Eckhard Hempel ,  Martin Hoheisel ,  Barbara Matthis ,  Franz Pfeiffer ,  Stefan Popescu

IPC: G21K1/06 ,  G02B5/18 ,  B23P17/00

CPC classification number: A61B6/06 ,  A61B6/03 ,  A61B6/4092 ,  A61B6/4291 ,  A61B6/484 ,  G01T1/00 ,  G21K1/025 ,  G21K1/06 ,  G21K2207/005 ,  Y10T29/49

Abstract: In a method for the production of x-ray-optical gratings composed of a first material forming of periodically arranged grating webs and grating openings, a second material is applied by electroplating to fill the grid openings. The electroplating is continued until a cohesive layer of the second material with uniform height is created over the grating webs with this layer having a large absorption coefficient, the absorption properties of the grating structure of the grating are homogenized, so an improvement of the measurement signals that are generated with this grating is improved. Moreover, the mechanical stability of gratings produced in such a manner is improved.

Abstract translation: 在用于生产由形成周期性布置的光栅幅材和光栅开口的第一材料组成的x射线光栅的方法中，通过电镀施加第二材料以填充栅格开口。 电镀继续进行，直到在光栅幅面上形成具有均匀高度的第二材料的内聚层，该层具有大的吸收系数，光栅的光栅结构的吸收特性被均匀化，因此测量信号的改进 改善了用该光栅产生的光栅。 此外，改善了以这种方式制造的光栅的机械稳定性。

公开(公告)号：US07653177B2

公开(公告)日：2010-01-26

申请号：US12213945

申请日：2008-06-26

Applicant: Joachim Baumann ,  Christian David ,  Martin Engelhardt ,  Jörg Freudenberger ,  Eckhard Hempel ,  Martin Hoheisel ,  Matthias Honal ,  Thomas Mertelmeier ,  Franz Pfeiffer ,  Stefan Popescu ,  Manfred Schuster

Inventor： Joachim Baumann ,  Christian David ,  Martin Engelhardt ,  Jörg Freudenberger ,  Eckhard Hempel ,  Martin Hoheisel ,  Matthias Honal ,  Thomas Mertelmeier ,  Franz Pfeiffer ,  Stefan Popescu ,  Manfred Schuster

IPC: G01N23/20

CPC classification number: G01N23/20 ,  A61B6/484 ,  A61K49/0414 ,  G01N2223/303 ,  G21K2207/005

Abstract: A method and a measurement system are disclosed for the noninvasive determination of properties of an object to be examined and to the use of a contrast medium for X-ray phase-contrast measurement. in at least one embodiment of the invention, a mixture (suspension) consisting of a base liquid and a multiplicity of particles contained therein is used, the refractive index of the base liquid being different to the refractive index of the particles.

Abstract translation: 公开了一种方法和测量系统，用于无创测定被检查物体的性质以及使用造影剂进行X射线相位测量。 在本发明的至少一个实施方案中，使用由基础液体和其中包含的多个颗粒组成的混合物（悬浮液），所述基础液体的折射率不同于颗粒的折射率。

公开(公告)号：US20100012854A1

公开(公告)日：2010-01-21

申请号：US12504760

申请日：2009-07-17

Applicant: Martin Hoheisel ,  Klaus Lowack

Inventor： Martin Hoheisel ,  Klaus Lowack

IPC: G01J1/58

CPC classification number: G21K4/00 ,  G21K2004/12

Abstract: A scintillator plate has a radiation-permeable substrate on which a scintillator layer is applied. The substrate is composed of a cellular metallic material and has a smooth, closed outer skin. Such a scintillator plate has high mechanical stability with good radiation permeability.

Abstract translation: 闪烁体板具有辐射透射性基底，在其上施加闪烁体层。 基底由细胞金属材料组成，具有光滑，封闭的外皮。 这种闪烁体板具有高的机械稳定性和良好的辐射透过性。

公开(公告)号：US07561658B2

公开(公告)日：2009-07-14

申请号：US12222349

申请日：2008-08-07

Applicant: Eckhard Hempel ,  Martin Hoheisel ,  Stefan Popescu ,  Rainer Raupach

Inventor： Eckhard Hempel ,  Martin Hoheisel ,  Stefan Popescu ,  Rainer Raupach

IPC: A61B6/00

CPC classification number: A61B6/032 ,  A61B6/037 ,  A61B6/484 ,  A61B6/503 ,  A61B6/507

Abstract: A method and an x-ray computed tomography system are disclosed for visualizing at least two different types of cardiac tissue, such as normally perfused tissue, hypoperfused tissue and scarred tissue. In at least one embodiment, this is done by use of an imaging tomographic recording technique with the aid of x-ray radiation, wherein at least one cardiac region of a patient is scanned by x-ray radiation which passes through a first grating for the passing-through x-ray radiation, designed as an absorption grating, prior to reaching the patient, and at least the locally caused phase-shifts of the x-ray radiation in the cardiac region are also made detectable by using a second grating for the passing-through x-ray radiation, designed as a phase grating, downstream of the patient in the emission direction, and the spatial distribution of these shifts is measured and reconstructed, wherein an average specific phase-shift value is assigned to each spatial unit, wherein each of the abovementioned tissue types are assigned to a region of a typical specific phase-shift value and at least one region assigned to a tissue type is optically highlighted in a view of the cardiac region.

Abstract translation: 公开了一种方法和x射线计算机断层摄影系统，用于可视化至少两种不同类型的心脏组织，例如通常灌注的组织，低灌注组织和瘢痕组织。 在至少一个实施例中，这通过使用借助于X射线辐射的成像断层摄影记录技术来完成，其中患者的至少一个心脏区域被x射线辐射扫描，X射线辐射通过第一光栅 在到达患者之前设计为吸收光栅的穿透X射线辐射以及至少在心脏区域中的x射线辐射的局部引起的相移也可以通过使用第二光栅来检测 测量并重构这些偏移的空间分布，其中平均特定相移值被分配给每个空间单元，其中， 其中上述组织类型中的每一种被分配给典型的特定相移值的区域，并且指定为组织类型的至少一个区域在心脏区域的视图中被光学突出显示。

公开(公告)号：US20090003526A1

公开(公告)日：2009-01-01

申请号：US12213945

申请日：2008-06-26

Applicant: Joachim Baumann ,  Christian David ,  Martin Engelhardt ,  Jorg Freudenberger ,  Eckhard Hempel ,  Martin Hoheisel ,  Matthias Honal ,  Thomas Mertelmeier ,  Franz Pfeiffer ,  Stefan Popescu ,  Manfred Schuster

Inventor： Joachim Baumann ,  Christian David ,  Martin Engelhardt ,  Jorg Freudenberger ,  Eckhard Hempel ,  Martin Hoheisel ,  Matthias Honal ,  Thomas Mertelmeier ,  Franz Pfeiffer ,  Stefan Popescu ,  Manfred Schuster

IPC: G01N23/20

CPC classification number: G01N23/20 ,  A61B6/484 ,  A61K49/0414 ,  G01N2223/303 ,  G21K2207/005

Abstract: A method and a measurement system are disclosed for the noninvasive determination of properties of an object to be examined and to the use of a contrast medium for X-ray phase-contrast measurement. in at least one embodiment of the invention, a mixture (suspension) consisting of a base liquid and a multiplicity of particles contained therein is used, the refractive index of the base liquid being different to the refractive index of the particles.

Abstract translation: 公开了一种方法和测量系统，用于无创测定被检查物体的性质以及使用造影剂进行X射线相位测量。 在本发明的至少一个实施方案中，使用由基础液体和其中包含的多个颗粒组成的混合物（悬浮液），所述基础液体的折射率不同于颗粒的折射率。

公开(公告)号：US07372944B2

公开(公告)日：2008-05-13

申请号：US11352716

申请日：2006-02-13

Applicant: Philipp Bernhardt ,  Martin Hoheisel

Inventor： Philipp Bernhardt ,  Martin Hoheisel

IPC: H05G1/22

CPC classification number: A61B6/542 ,  A61B6/503 ,  A61B6/545

Abstract: The invention relates to an x-ray diagnostics device having an x-ray tube for generating x-rays operated by a high voltage generator, having an x-ray detector for converting incident x-rays into electrical signals, having an image processing system and a control device for the duration of the x-ray pulse, in which parameters of the x-ray diagnostics device can be adjusted, with a computing unit being assigned to the control device, said computing unit determining the spatial frequency-dependent signal-to-noise ratio on the basis of the parameters and calculating therefrom the duration of the x-ray pulse and/or the remaining parameters required for a recording. The invention further relates to a method of this type for controlling the x-ray diagnostics device, in which the duration of the x-ray pulse is controlled such that the recognizability of relevant, moved objects is maximal.

Abstract translation: 本发明涉及一种具有用于产生由高压发生器操作的x射线的X射线管的X射线诊断装置，具有用于将入射的X射线转换为电信号的X射线检测器，具有图像处理系统和 控制装置，其中X射线脉冲的持续时间可以通过计算单元被分配给控制装置来调节x射线诊断装置的参数，所述计算单元确定空间频率相关信号到 - 根据参数计算噪声比，并从中计算x射线脉冲的持续时间和/或记录所需的剩余参数。 本发明还涉及这种类型的用于控制X射线诊断装置的方法，其中控制x射线脉冲的持续时间，使得相关的被移动物体的可识别性是最大的。

公开(公告)号：US20070262266A1

公开(公告)日：2007-11-15

申请号：US11628190

申请日：2005-05-31

Applicant: Martin Hoheisel ,  Markus Schild ,  Martin Spahn

Inventor： Martin Hoheisel ,  Markus Schild ,  Martin Spahn

IPC: G01N23/223

CPC classification number: G01T1/202

Abstract: An x-ray detector has a light sensitive detector that is substantially transparent to x-rays, and has opposite sides that are permeated by incoming x-rays. At each of said opposite sides, a scintillator is arranged on the sensor that converts the incoming x-rays into light at each of said opposite sides.

Abstract translation: X射线检测器具有对x射线基本上透明的光敏检测器，并且具有被入射的X射线渗透的相对侧。 在每个所述相对侧，在传感器上布置闪烁体，其将进入的X射线转换成每个所述相对侧的光。

公开(公告)号：US20070183583A1

公开(公告)日：2007-08-09

申请号：US11700172

申请日：2007-01-31

Applicant: Joachim Baumann ,  Christian David ,  Martin Engelhardt ,  Jorg Freudenberger ,  Eckhard Hempel ,  Martin Hoheisel ,  Thomas Mertelmeier ,  Franz Pfeiffer ,  Stefan Popescu ,  Manfred Schuster

Inventor： Joachim Baumann ,  Christian David ,  Martin Engelhardt ,  Jorg Freudenberger ,  Eckhard Hempel ,  Martin Hoheisel ,  Thomas Mertelmeier ,  Franz Pfeiffer ,  Stefan Popescu ,  Manfred Schuster

IPC: G21K1/00

CPC classification number: G21K1/06 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4092 ,  A61B6/4233 ,  A61B6/4291 ,  A61B6/484 ,  G21K2207/005

Abstract: A focus-detector arrangement and an X-ray apparatus for generating projective or tomographic phase contrast recordings of a subject are disclosed. In at least one embodiment, the focus-detector arrangement includes a radiation source with a focus, arranged on a first side of the subject, for generating a fan-shaped or conical beam of rays; at least one X-ray optical grating arranged in the beam path, with at least one phase grating arranged on the opposite second side of the subject in the beam path generating an interference pattern of the X-radiation preferably, in a particular energy range; and an analysis-detector system which detects at least the interference pattern generated by the phase grating in respect of its phase shift with position resolution. According to at least one embodiment of the invention, at least one X-ray optical grating including bars which are free from overhangs form shadows in the beam path of the fan-shaped or conical beam of rays.

Abstract translation: 公开了一种聚焦检测器装置和用于产生对象的投影或层析相位对比记录的X射线装置。 在至少一个实施例中，焦点检测器装置包括布置在被检体的第一侧上的具有焦点的辐射源，用于产生扇形或锥形光束束; 布置在所述光束路径中的至少一个X射线光栅，其中至少一个相位光栅布置在所述束路径中的所述对象的相对的第二侧上，优选地在特定能量范围内产生所述X射线的干涉图案; 以及分析检测器系统，其至少检测相位光栅相对于其相移与位置分辨率产生的干涉图案。 根据本发明的至少一个实施例，至少一个X射线光栅，其包括不具有突出端的杆，在扇形或锥形光束的光束路径中形成阴影。

公开(公告)号：US20070140429A1

公开(公告)日：2007-06-21

申请号：US11432242

申请日：2006-05-11

Applicant: Martin Hoheisel

Inventor： Martin Hoheisel

IPC: H05G1/54

CPC classification number: A61B6/08 ,  A61B6/589

Abstract: In the English translation document, please delete the title of the abstract at page 11 line 3, as follows: In the English translation document, please amend the paragraph at page 11 lines 5-11, as follows: The invention relates to a method for monitoring an x-ray apparatus. To prevent the application of a harmful x-ray dose, it is proposed in accordance with the invention to compare a distance value indicating a distance between an x-ray source and a surface of a patient with a predetermined mini-mum distance value and to generate a warning signal, if the distance value is smaller than the minimum distance value. In the English translation document, please delete the term—FIG.—at page 11 line 13.

Abstract translation: 在英文译文中，请删除第11行第3行摘要的标题如下：在英文翻译文件中，请修改第11-11行第5-11段的段落，具体如下：本发明涉及一种 监测x射线设备。 为了防止施加有害的x射线剂量，根据本发明提出了将具有预定的微距离值的x射线源和患者的表面之间的距离的距离值进行比较，以及 如果距离值小于最小距离值，则生成警告信号。 在英文译文中，请删除第13页第13行中的术语。