公开(公告)号：US20080015213A1

公开(公告)日：2008-01-17

申请号：US11791465

申请日：2005-11-18

申请人： Philippe Nantermet ,  Hemaka Rajapakse ,  Harold Selnick ,  Keith Moore

发明人： Philippe Nantermet ,  Hemaka Rajapakse ,  Harold Selnick ,  Keith Moore

IPC分类号： A61K31/4353 ,  A61P25/28 ,  C07D221/06 ,  C07D267/00

CPC分类号： C07D491/08

摘要： The present invention is directed to macrocyclic aminopyridyl compounds represented by general formula (I), which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

摘要翻译： 本发明涉及由通式（I）表示的大环氨基吡啶基化合物，其是β-分泌酶的抑制剂，并且其可用于治疗其中涉及β-分泌酶的疾病，例如阿尔茨海默氏病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。

公开(公告)号：US20060107536A1

公开(公告)日：2006-05-25

申请号：US11328519

申请日：2006-01-09

申请人： John Buck ,  James Bascom ,  Keith Moore

发明人： John Buck ,  James Bascom ,  Keith Moore

IPC分类号： B23D45/16

CPC分类号： H02J7/0045 ,  B25F5/02 ,  B27B9/02 ,  H01M2/10 ,  H01M2/1022 ,  H01M2/1055 ,  H01M2/30 ,  Y10S30/01 ,  Y10T307/50

摘要： A battery powered circular saw includes a rechargeable battery removably attached to the housing and an adjustable shoe pivotally attached to the housing for controlling a depth of cut. A locking mechanism for preventing relative movement between the adjustable shoe and the housing includes a clamp that is located so as to permit the battery pack to be inserted to and removed from a rear end of the housing in a direction that is generally parallel to a plane in which the circular saw blade is disposed.

摘要翻译： 电池供电的圆锯包括可拆卸地附接到壳体的可再充电电池和可枢转地附接到壳体的可调整滑块，用于控制切割深度。 用于防止可调节鞋和壳体之间的相对移动的锁定机构包括夹具，其被定位成允许电池组沿着大致平行于平面的方向插入壳体的后端并从壳体的后端移除 其中设置有圆锯片。

公开(公告)号：US20050262111A1

公开(公告)日：2005-11-24

申请号：US10850406

申请日：2004-05-21

申请人： Jun Li ,  Keith Moore

发明人： Jun Li ,  Keith Moore

IPC分类号： G06F9/46 ,  G06F17/00

CPC分类号： G06F9/548 ,  G06F9/465 ,  G06F2209/462

摘要： A system for object discovery in heterogeneous object systems includes a fixed object system having a registry. A callee object having a rendezvous name is registered in the registry of the fixed object system under the rendezvous name. The system also includes an adaptive object system having a remote procedure call protocol abstraction layer. The remote procedure call protocol abstraction layer is configured to access the registry of the fixed object system.

摘要翻译： 异构对象系统中的对象发现系统包括具有注册表的固定对象系统。 具有会合名称的被叫方对象在会合名称下的固定对象系统的注册表中注册。 该系统还包括具有远程过程调用协议抽象层的自适应对象系统。 远程过程调用协议抽象层被配置为访问固定对象系统的注册表。

公开(公告)号：US20050245614A1

公开(公告)日：2005-11-03

申请号：US11072162

申请日：2005-03-04

申请人： Keith Moore ,  Ralph Heasley ,  Jeffrey Greiwe

发明人： Keith Moore ,  Ralph Heasley ,  Jeffrey Greiwe

IPC分类号： A61K31/19

CPC分类号： A61K31/19

摘要： Disclosed are oral tranexamic acid formulations and methods of treatment therewith.

摘要翻译： 公开了口服氨甲环酸制剂及其治疗方法。

公开(公告)号：US20050080076A1

公开(公告)日：2005-04-14

申请号：US10681431

申请日：2003-10-08

申请人： Keith Moore ,  Ralph Heasley

发明人： Keith Moore ,  Ralph Heasley

IPC分类号： A61K31/382 ,  C07D279/24 ,  C07D279/28 ,  A61K31/5415

CPC分类号： A61K31/382 ,  C07D279/28

摘要： A pharmaceutically active N-desmethyl levomepromazine (abbreviated NDM LMP) and method of use. NDM LMP has substantially the same therapeutic effects as the parent levomepromazine but is subject to less disposition (e.g. presystemic and systemic metabolism) and thus has improved properties over the parent.

摘要翻译： 药物活性N-去甲基左美丙嗪（缩写为NDM LMP）及其使用方法。 NDM LMP具有与母体左美他嗪基本上相同的治疗效果，但是受到较少的处置（例如系统和全身代谢），因此具有比母体更好的性质。

公开(公告)号：US06173309B2

公开(公告)日：2001-01-09

申请号：US08803404

申请日：1997-02-20

申请人： Evan Kirshenbaum ,  Keith Moore ,  Walter R. Underwood

发明人： Evan Kirshenbaum ,  Keith Moore ,  Walter R. Underwood

IPC分类号： G06F900

CPC分类号： G06F9/44521 ,  G06F9/46

摘要： User code is operated in either a multithreaded or non-threaded programming environment by linking the code to different libraries. A standard thread library is linked with the code when operated in a multithreaded mode. A null thread library is linked to the code to operate in a non-threaded mode. The different libraries are linked to the user code through a common application programming interface allowing the same thread function calls to operate in either the multithreaded or non-threaded mode. The null thread library implements thread function calls as blocking functions which synchronize thread launches while eliminating the performance and memory overhead required in multithreaded processes.

摘要翻译： 通过将代码链接到不同的库，用户代码在多线程或非线程编程环境中运行。 当以多线程模式运行时，标准线程库与代码链接。 空线程库链接到代码以在非线程模式下操作。 不同的库通过通用应用程序编程接口链接到用户代码，允许相同的线程函数调用以多线程或非线程模式运行。 空线程库将线程函数调用作为同步线程启动的阻塞函数，同时消除了多线程进程中所需的性能和内存开销。

公开(公告)号：US5396037A

公开(公告)日：1995-03-07

申请号：US208371

申请日：1994-03-10

申请人： Keith Moore ,  Luke J. LaPanne

发明人： Keith Moore ,  Luke J. LaPanne

IPC分类号： H01H23/14 ,  H01H3/04

CPC分类号： H01H23/141

摘要： An elongate support rod has a handle at one end and damp structure at its other end, with the damp structure arranged for mounting to a light switch lever, wherein the handle is arranged to provide for illumination for indication of the structure, such that a child and the like may be availed to project the structure to effect actuation of an associated light switch member.

摘要翻译： 细长的支撑杆在一端具有手柄并在其另一端处具有阻尼结构，其中阻尼结构被布置成安装到灯开关杆，其中手柄被设置成提供用于指示结构的照明，使得儿童 可以利用这样的方式投射结构以实现相关联的光开关构件的致动。