Abstract:
A detector is described having readout electronics integrated in the photodetector layer. The detector may be configured to acquire both energy-integrated and photon-counting data. In one implementation, the detector is also configured with control logic to select between the jointly generated photon-counting and energy-integrated data.
Abstract:
The present approaches relates to the use of silicon-based energy-discriminating, photon-counting detectors, such as for use in X-ray based imaging including computed tomography. The described approaches address the resolution and classification of X-ray photons affected by Compton scatter, which may be detected as having energy levels below their proper level due to collision or deflection events.
Abstract:
Design and use of an administered drug in the form of a nanoparticle or molecule is described. In certain examples, the nanoparticle has a core and a shell surrounding the core. The core may be configured or designed to provide useful X-ray attenuating properties, gamma ray emission properties, magnetic properties, or therapeutic effects. In certain aspects, the nanoparticle or molecule is sized so as to either distribute from or remain in the blood pool, while still being eliminated by the kidneys.
Abstract:
The present approach relates to the use of energy-resolved, photon-counting detectors, such as CZT- or CdTe-based detectors, to acquire spectral information that is not available with conventional energy-integrating detectors. In certain embodiments, the present approach discussed reduces or eliminates spectral contamination incurred by transient signals in neighboring pixels in designs employing coincidence logic and shaping amplifiers with short shaping times.
Abstract:
The present approach relates to the use of energy-resolved, photon-counting detectors, such as CZT- or CdTe-based detectors, to acquire spectral information that is not available with conventional energy-integrating detectors. In certain embodiments, the present approach discussed reduces or eliminates spectral contamination incurred by transient signals in neighboring pixels in designs employing coincidence logic and shaping amplifiers with short shaping times.
Abstract:
Acquisition of X-ray transmission data at three or more energy levels is described. Various implementations utilize generator waveforms that utilize fast-switching, slow-switching, or a combination of fast- and slow-switching to transition between X-ray energy levels. In addition, various sampling arrangements for sampling and/or binning three or more energy levels of X-ray transmission data are discussed. The use of these data in subsequent processing steps, such for material decomposition and/or improvement of dual-energy material decomposition processing, are also described.
Abstract:
The present approach provides a non-invasive methodology for estimation of coronary flow and/or fractional flow reserve. In certain implementations, various approaches for personalizing blood flow models of the coronary vasculature are described. The described personalization approaches involve patient-specific measurements and do not assume or rely on the resting coronary flow being proportional to myocardial mass. Consequently, there are fewer limitations in using these approaches to obtain coronary flow and/or fractional flow reserve estimates non-invasively.
Abstract:
A signal processing method is disclosed, which includes detecting a total intensity of X-rays passing through an object comprising multiple materials; obtaining at least one set of basis information of basis material information of the multiple materials and basis component information of photon-electric absorption basis component and Compton scattering basis component of the object; estimating a scatter intensity component of the detected X-rays based on the at least one set of basis information and the detected total intensity; and obtaining an intensity estimate of primary X-rays incident on a detector based on the detected total intensity and the estimated scatter intensity component. An imaging system adopting the above signal processing method is also disclosed.
Abstract:
Acquisition of X-ray transmission data at three or more energy levels is described. Various implementations utilize generator waveforms that utilize fast-switching, slow-switching, or a combination of fast- and slow-switching to transition between X-ray energy levels. In addition, various sampling arrangements for sampling and/or binning three or more energy levels of X-ray transmission data are discussed. The use of these data in subsequent processing steps, such for material decomposition and/or improvement of dual-energy material decomposition processing, are also described.
Abstract:
A method of generating an image in one embodiment includes acquiring, with a computed tomography (CT) acquisition unit, CT projection data from at least a region of interest (ROI), and concurrently acquiring, with a magnetic resonance (MR) acquisition unit, MR imaging information of at least a portion of the ROI. The method also includes determining a motion of the at least a portion of the ROI using the MR imaging information, and reconstructing the image using the CT projection data. Reconstructing the image includes motion correcting the CT projection data based on the motion determined using the MR imaging information.