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公开(公告)号：US20220096227A1
公开(公告)日：2022-03-31
申请号：US17643750
申请日：2021-12-10
IPC分类号： A61F2/24
摘要： A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window for enhanced access to the commissure posts and leaflets. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation.
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公开(公告)号：US11197756B2
公开(公告)日：2021-12-14
申请号：US16459343
申请日：2019-07-01
摘要： A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window for enhanced access to the commissure posts and leaflets. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation.
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公开(公告)号：US11185321B2
公开(公告)日：2021-11-30
申请号：US16436829
申请日：2019-06-10
发明人： Travis Zenyo Oba , Michael C. Murad , Manouchehr A. Miraki , Anthony P. Carcia , Fabian Daniel Schroeder , Raffaele Mazzei , Tyler Douglas Smith
摘要： Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.
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公开(公告)号：US11007058B2
公开(公告)日：2021-05-18
申请号：US16052775
申请日：2018-08-02
摘要： A valved conduit including a bioprosthetic aortic heart valve connected to a tubular conduit graft forming an ascending aorta. The conduit graft may attach to the heart valve in a manner that facilitates a redo operation in which the valve is replaced with another valve. A sewing ring may be pre-attached to the inflow end of the graft, and then the valve connected to a delivery holder advanced into the graft and secured to the sewing ring. Dry bioprosthetic valves coupled with conduit grafts sealed with a bioresorbable medium can be stored with the delivery holder.
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公开(公告)号：US10772725B2
公开(公告)日：2020-09-15
申请号：US15865006
申请日：2018-01-08
摘要： An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
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公开(公告)号：US20200060821A1
公开(公告)日：2020-02-27
申请号：US16673487
申请日：2019-11-04
发明人： Brian S. Conklin , Michael C. Murad
IPC分类号： A61F2/24
摘要： A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.
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公开(公告)号：US20180289477A1
公开(公告)日：2018-10-11
申请号：US15481283
申请日：2017-04-06
发明人： Brian S. Conklin , Michael C. Murad
IPC分类号： A61F2/24
摘要： A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.
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公开(公告)号：US09861478B2
公开(公告)日：2018-01-09
申请号：US15076107
申请日：2016-03-21
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2409 , A61F2/2412 , A61F2220/0075 , A61F2230/0006 , A61F2250/001
摘要： An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
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39.发明申请MULTIPLE-FIRING SECURING DEVICE AND METHODS FOR USING AND MANUFACTURING SAME 审中-公开多重安全保护装置及其使用和制造方法公开(公告)号：US20160166248A1
公开(公告)日：2016-06-16
申请号：US14965323
申请日：2015-12-10
发明人： Derek Dee Deville , Kevin W. Smith , Michael Walter Kirk , Carlos Rivera , George Nunez , Thomas O. Bales, JR. , Korey Kline , Matthew A. Palmer , M. Sean McBrayer , Richard Cartledge , Max Pierre Mendez , Hengchu Cao , Anthony Peter Carcia , Kevin Dang , Carey Hendsbee , Brent K. Hoffman , Brian R. Jacobs , Mohammad Jafari , Brian Janish , Jeffrey L. Mahoney , Raffaele Mazzei , Manouchehr A. Miraki , Ryan Moehle , Jeremiah Morgan , Michael C. Murad , Travis Zenyo Oba , Ralph Schneider , Fabian Daniel Schroeder , Tyler Douglas Smith , Ming H. Wu
IPC分类号： A61B17/04
CPC分类号： A61B17/0485 , A61B17/0467 , A61B17/0487 , A61B2017/00017 , A61B2017/00119 , A61B2017/00349 , A61B2017/00358 , A61B2017/00398 , A61B2017/00477 , A61B2017/00734 , A61B2017/00876 , A61B2017/00902 , A61B2017/0488 , A61B2017/0496 , A61B2090/064 , A61B2090/0807 , A61B2090/309 , A61B2090/3937
摘要： A multiple-fire securing device includes a hollow outer shaft, a reloader, a reloader movement assembly, a rail, and securing structures each defining an inner securing orifice. The reloader longitudinally moves within the outer shaft and has a distal end shaped to temporarily contact one of the securing structures. The rail is disposed within the reloader and has an installing location. The securing structures are disposed on the rail. The reloader movement assembly moves the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position and moves the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures. The second and successive securing structures are moved one at a time to the installing location.
摘要翻译： 多重火焰固定装置包括中空的外轴，重新装载机，重装机运动组件，轨道和固定结构，每个限定内固定孔。 重新装载机在外轴内纵向移动并且具有成形为临时接触其中一个固定结构的远端。 轨道设置在重新装载机内并具有安装位置。 固定结构设置在轨道上。 重新装载机构移动组件沿远侧方向纵向运动重新装载机，以将第一固定结构从第一近端位置传送到安装位置，并将重新装载机向近侧移动远离安装位置而不用第一固定结构移动到远端 的重新加载器临时接触第二个固定结构。 第二和连续的固定结构一次一个地移动到安装位置。
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公开(公告)号：US20150313712A1
公开(公告)日：2015-11-05
申请号：US14797110
申请日：2015-07-11
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B2017/00243 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2454 , A61F2230/0071
摘要： A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window for enhanced access to the commissure posts and leaflets. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation.
摘要翻译： 用于假体二尖瓣心脏瓣膜的保持器，其附接到瓣膜的流入端，并且包括将心脏瓣膜连接柱向内弯曲的简单张紧机构，以帮助防止缝合线循环。 张紧机构可以包括保持器的相对可移动的环或具有张量或可旋转旋钮的大体上一体的保持器。 连接缝合线通过保持器内部的通道，沿着流出方向沿阀门连接柱移动，出现在后端，并在阀的流出侧相互交叉。 手柄靠近座位，通过中央窗口增加对心脏瓣膜的可视化和访问，以增强对连接柱和传单的使用。 保持器由非金属材料构成，以避免干扰成像装置，并且手柄符合人体工程学地弯曲和成形以便于操纵。
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