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公开(公告)号：US09470801B2
公开(公告)日：2016-10-18
申请号：US12087150
申请日：2006-12-28
Applicant: Omer Ziv , Ran Ravhon , Eli Dichterman , Leonid Gluhovsky , Shlomo Ben-Haim , Benny Rousso
Inventor： Omer Ziv , Ran Ravhon , Eli Dichterman , Leonid Gluhovsky , Shlomo Ben-Haim , Benny Rousso
CPC classification number: G01T1/1644 , A61B5/055 , A61B5/415 , A61B5/416 , A61B5/418 , A61B5/7285 , A61B6/037 , A61B6/503 , A61B6/541 , A61B8/0883 , A61B8/543 , G01T1/1663 , G06T11/005 , G06T11/006 , G06T11/008 , G06T2207/10104 , G06T2207/30048 , G06T2211/436
Abstract: A method for reconstructing a radioactive emission image of an overall volume having first and second volumetric regions, each volumetric region having respectively independent dynamic characteristics. The method comprises the following steps: a) obtaining radioactive emissions from the overall volume, including the volumetric regions, b) reconstructing an initial radioactive emission image of the volumetric region according to the radioactive emissions, c) segmenting the initial radioactive emission image to delineate the first and second volumetric regions, and d) separately reconstructing the first and the second volumetric regions according to the respectively independent dynamic characteristics.
Abstract translation: 一种用于重建具有第一和第二体积区域的总体积的放射性发射图像的方法，每个体积区域具有分别独立的动态特性。 该方法包括以下步骤：a）从总体积（包括体积区域）获得放射性发射，b）根据放射性发射重建体积区域的初始放射性发射图像，c）分割初始放射性发射图像以描绘 第一和第二体积区域，以及d）根据分别独立的动态特性分别重建第一和第二体积区域。
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公开(公告)号：US09462971B2
公开(公告)日：2016-10-11
申请号：US13721839
申请日：2012-12-20
Applicant: Gearbox, LLC
Inventor： Dennis J. Rivet , Roderick A. Hyde
CPC classification number: A61B5/150061 , A61B5/0031 , A61B5/14 , A61B5/14503 , A61B5/14546 , A61B5/15 , A61B5/150022 , A61B5/150221 , A61B5/150229 , A61B5/150251 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150748 , A61B5/150755 , A61B5/150793 , A61B5/150877 , A61B5/15113 , A61B5/153 , A61B5/155 , A61B5/157 , A61B5/415 , A61B5/418 , A61B5/6842 , A61B5/6861 , A61N1/325 , A61N2/00
Abstract: A method may include collecting at least one analyte from within a body, ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and receiving the ejected at least one analyte outside the body. A system may include a means for collecting at least one analyte from within a body, a means for ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and a means for receiving the ejected at least one analyte outside the body.
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23.发明授权
公开(公告)号：US09451884B2
公开(公告)日：2016-09-27
申请号：US13253767
申请日：2011-10-05
Applicant: Vladimir Pavlovich Zharov , Ekaterina Galanzha
Inventor： Vladimir Pavlovich Zharov , Ekaterina Galanzha
IPC: A61B8/00 , A61B5/00 , A61B8/06 , A61K49/22 , B03C1/28 , B03C1/30 , G01N21/17 , G01N29/24 , G01N29/44 , A61B8/08 , A61B18/18 , A61B18/20 , G01N15/14
CPC classification number: A61B18/245 , A61B5/0059 , A61B5/0095 , A61B5/02007 , A61B5/14535 , A61B5/1495 , A61B5/412 , A61B5/415 , A61B5/416 , A61B5/418 , A61B5/4839 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61B5/7455 , A61B5/746 , A61B8/06 , A61B8/08 , A61B8/481 , A61B18/1815 , A61B18/20 , A61B2018/0041 , A61B2018/00577 , A61B2018/0088 , A61K49/22 , B03C1/288 , B03C1/30 , B03C2201/06 , B03C2201/26 , G01N15/1425 , G01N15/1434 , G01N15/147 , G01N21/1702 , G01N29/2418 , G01N29/4427 , G01N2015/1477 , G01N2201/0221
Abstract: A device and method of using the device to detect the presence and composition of clots and other target objects in a circulatory vessel of a living subject is described. In particular, devices and methods of detecting the presence and composition of clots and other target objects in a circulatory vessel of a living subject using in vivo photoacoustic flow cytometry techniques is described.
Abstract translation: 描述了使用该装置来检测在活体的循环血管中凝块和其它目标物体的存在和组成的装置和方法。 具体地，描述了使用体内光声流式细胞术技术来检测活体的循环血管中凝块和其它目标物体的存在和组成的装置和方法。
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24.发明授权MRI-guided interventional systems that can track and generate dynamic visualizations of flexible intrabody devices in near real time 有权MRI引导的介入系统可以实时跟踪和生成灵活的内部装置的动态可视化
公开(公告)号：US09439735B2
公开(公告)日：2016-09-13
申请号：US12796017
申请日：2010-06-08
Applicant: Michael Guttman , Kimble L. Jenkins , Peter Piferi , Kamal Vij
Inventor： Michael Guttman , Kimble L. Jenkins , Peter Piferi , Kamal Vij
CPC classification number: A61B5/418 , A61B5/055 , A61B5/415 , A61B18/1492 , A61B34/10 , A61B34/20 , A61B34/25 , A61B2017/00053 , A61B2017/00243 , A61B2018/00029 , A61B2018/00839 , A61B2018/1472 , A61B2034/101 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/252 , A61B2090/374
Abstract: MRI guided cardiac interventional systems are configured to generate dynamic (interactive) visualizations of patient anatomy and medical devices during an MRI-guided procedure and may also include at least one user selectable 3-D volumetric (tissue characterization) map of target anatomy, e.g., a defined portion of the heart.
Abstract translation: MRI引导的心脏介入系统被配置为在MRI引导过程期间生成患者解剖学和医疗装置的动态（交互）可视化，并且还可以包括目标解剖结构的至少一个用户可选择的3-D体积（组织表征）图， 心脏的定义部分。
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25.发明申请DEVICE FOR MEASURING THE CIRCUMFERENCE OF AN OBJECT, IN PARTICULAR A LIMB 审中-公开用于测量物体的轮廓的装置，特别是一个LIMB
公开(公告)号：US20160113549A1
公开(公告)日：2016-04-28
申请号：US14894314
申请日：2014-05-28
Applicant: JUST A NEW HEALTH
Inventor： Joseph Harfouche
CPC classification number: A61B5/1075 , A61B5/415 , A61B5/418 , A61B5/6824 , A61B5/6828 , A61B5/6831
Abstract: The application relates to a device for the iterative measurement of the circumference of an object, in particular a limb, comprising: a first longitudinal graduated measuring element having a first longitudinal direction, arranged to be placed alongside said object, in particular alongside said limb and defining a slide, a distal strap and a proximal strap each located in a plane substantially perpendicular to said longitudinal direction, and a slider engaging with said slide, linked to a second longitudinal graduated measuring element, said slider having a hole for the slide to pass through and being positioned between said distal strap and said proximal strap.
Abstract translation: 本申请涉及一种用于迭代测量物体，特别是肢体的圆周的装置，包括：具有第一纵向方向的第一纵向刻度测量元件，被布置成与所述物体一起放置，特别是与所述肢体一起放置， 限定滑动件，远端皮带和近端皮带，每个位于基本上垂直于所述纵向方向的平面中;以及与所述滑块接合的滑块，其连接到第二纵向刻度测量元件，所述滑块具有用于滑块通过的孔 通过并定位在所述远端带和所述近端带之间。
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公开(公告)号：US09311722B2
公开(公告)日：2016-04-12
申请号：US14181306
申请日：2014-02-14
Applicant: VisEn Medical, Inc.
Inventor： Wael I. Yared , Pouyan Mohajerani , Joshua Kempner
CPC classification number: G06T11/005 , A61B5/0071 , A61B5/0073 , A61B5/415 , G01N21/4795 , G01N21/6456 , G01N2021/6439 , G01N2021/6491 , G06T11/003
Abstract: In certain embodiments, the invention relates to systems and methods for altering an image to compensate for variation in one or more physical and/or supervenient properties (e.g., optical absorption and/or scattering) in heterogeneous, diffuse tissue, thereby attenuating the effects of tissue waveguiding. The methods enable the proper identification of emission image regions that evidence waveguiding of electromagnetic radiation, and enables compensation of emission images for such waveguiding. The methods preserve the depth localization accuracy of the FMT approach and improve optical reconstruction in the targeted areas while eliminating spurious components of fluorescence from the acquired data set. Calibration methods for probe concentration mapping are also presented.
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公开(公告)号：US09289152B2
公开(公告)日：2016-03-22
申请号：US12531465
申请日：2008-03-14
Applicant: Marina Shaduri
Inventor： Marina Shaduri
CPC classification number: A61B5/05 , A61B5/0059 , A61B5/415 , A61B5/418 , H04N7/18
Abstract: The invention concerns a device for non-invasive detection of malignant processes in human body. Diagnostically informative optical data are obtained by exposing human fingertips to pulsed electric fields strong enough to initiate atmospheric pressure corona discharge. The device that provides reliable information useful for detection of cancer-specific spectral signatures comprises a transparent electrode (4) to generate electric impulses, which is covered by a rigid transparent insulator (3); a flexible transparent membrane (2) positioned loosely on the free surface of the rigid insulator to facilitate the recombination processes; a dark opaque membrane (1) positioned on the transparent membrane to eliminate spurious light; an image-receiving camera (5) mounted beneath the optically transparent electrode and a computer to operate the device and process recorded data. Proper arrangement of 3 dielectric layers and the recording of images when thermodynamic equilibrium is already established, significantly improves the reproducibility of optical data.
Abstract translation: 本发明涉及用于非侵入性检测人体恶性进程的装置。 通过将人类指尖暴露于足以引发大气压电晕放电的脉冲电场，获得诊断信息的光学数据。 提供可用于检测癌症特异性光谱特征的可靠信息的装置包括产生电脉冲的透明电极（4），其由刚性透明绝缘体（3）覆盖; 柔性透明膜（2）松散地定位在刚性绝缘体的自由表面上，以促进复合过程; 位于透明膜上的黑色不透明膜（1），以消除杂散光; 安装在光学透明电极下面的图像接收相机（5）和计算机来操作该设备并处理记录的数据。 3个电介质层的正确配置和当热力学平衡已经建立时记录图像，显着提高了光学数据的再现性。
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公开(公告)号：US09289135B2
公开(公告)日：2016-03-22
申请号：US14540404
申请日：2014-11-13
Applicant: Valencell, Inc.
Inventor： Steven Francis LeBoeuf , Jesse Berkley Tucker , Michael Edward Aumer
IPC: A61B5/00 , A61B5/0205 , G06F19/00 , A61B5/024 , H04R1/10 , A61B5/11 , A61B5/1455 , A61B5/0476 , A61B5/16 , F21V8/00 , A61B5/021 , A61B5/08 , A61B5/01 , A61B5/145 , A61B5/026 , A61B5/0295 , A61B5/091
CPC classification number: A61B5/7221 , A61B5/00 , A61B5/0013 , A61B5/002 , A61B5/0022 , A61B5/0024 , A61B5/0059 , A61B5/0082 , A61B5/0084 , A61B5/01 , A61B5/0205 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/02405 , A61B5/02416 , A61B5/02427 , A61B5/02433 , A61B5/026 , A61B5/0261 , A61B5/0295 , A61B5/0476 , A61B5/0816 , A61B5/091 , A61B5/11 , A61B5/1107 , A61B5/1118 , A61B5/14532 , A61B5/1455 , A61B5/14551 , A61B5/165 , A61B5/411 , A61B5/415 , A61B5/418 , A61B5/4812 , A61B5/4845 , A61B5/4848 , A61B5/486 , A61B5/4866 , A61B5/4875 , A61B5/4884 , A61B5/6803 , A61B5/6815 , A61B5/6816 , A61B5/6817 , A61B5/6819 , A61B5/6826 , A61B5/6838 , A61B5/7207 , A61B5/721 , A61B5/7214 , A61B5/725 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B5/7475 , A61B2560/0242 , A61B2560/0425 , A61B2560/0443 , A61B2562/0219 , A61B2562/0233 , G02B6/0001 , G06F19/00 , G06F19/3418 , H04R1/028 , H04R1/105 , H04R1/1091 , Y02A90/26
Abstract: A monitoring device includes a housing configured to be attached to a body of a subject. An optical emitter, optical detector, and sensor for measuring motion noise are located within the housing. Light transmissive material is in optical communication with the optical emitter and detector and is configured to deliver light from the optical emitter to one or more locations of the body of the subject and to collect light external to the housing and deliver the collected light to the detector. A signal processor is configured to receive and process signals produced by the optical detector and the motion noise sensor, and to remove noise from the signals produced by the optical detector. The signal processor may generate physiological parameters for the subject such as heart rate, blood flow, blood pressure, VO2max, heart rate variability, respiration rate, and blood gas/analyte level.
Abstract translation: 监视装置包括被配置为附接到被摄体的主体的壳体。 用于测量运动噪声的光发射器，光学检测器和传感器位于壳体内。 透光材料与光发射器和检测器光学通信，并且被配置为将光从光发射器传送到被摄体的身体的一个或多个位置并且收集外壳外部的光并将收集的光传送到检测器 。 信号处理器被配置为接收和处理由光学检测器和运动噪声传感器产生的信号，并且从由光学检测器产生的信号中去除噪声。 信号处理器可以产生对象的生理参数，例如心率，血流量，血压，VO2max，心率变异性，呼吸速率和血气/分析物水平。
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公开(公告)号：US09259290B2
公开(公告)日：2016-02-16
申请号：US12795945
申请日：2010-06-08
Applicant: Kimble L. Jenkins , Peter Piferi , Michael Guttman
Inventor： Kimble L. Jenkins , Peter Piferi , Michael Guttman
CPC classification number: A61B5/418 , A61B5/055 , A61B5/415 , A61B18/1492 , A61B34/10 , A61B34/20 , A61B34/25 , A61B2017/00053 , A61B2017/00243 , A61B2018/00029 , A61B2018/00839 , A61B2018/1472 , A61B2034/101 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/252 , A61B2090/374
Abstract: Systems to facilitate MRI-guided procedures are configured to generate proximity alerts for an MRI-guided procedure associated with at least one target site and/or at least one avoid zone.
Abstract translation: 用于促进MRI引导过程的系统被配置为产生与至少一个目标部位和/或至少一个避免区域相关联的MRI引导过程的接近警报。
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公开(公告)号：US20160025632A1
公开(公告)日：2016-01-28
申请号：US14847434
申请日：2015-09-08
Applicant: Lumicell, Inc.
Inventor： W. David Lee , Moungi G. Bawendi , Jorge Ferrer
IPC: G01N21/64 , A61B5/00 , G01N33/483
CPC classification number: G01N21/6486 , A61B5/0071 , A61B5/0084 , A61B5/0086 , A61B5/0091 , A61B5/415 , A61B5/418 , A61B5/4519 , A61B5/742 , A61B90/37 , A61B2090/373 , A61K49/0032 , G01N33/4833 , G01N2201/06113
Abstract: The present invention provides compositions and methods for imaging tumor resections.
Abstract translation: 本发明提供用于成像肿瘤切除术的组合物和方法。
