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公开(公告)号:US20230190114A1
公开(公告)日:2023-06-22
申请号:US18110135
申请日:2023-02-15
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
IPC: A61B5/02 , A61B5/00 , G09B23/30 , A61B34/10 , A61B5/318 , A61B5/319 , A61B5/339 , A61B5/341 , G06V10/00 , G06V10/764
CPC classification number: A61B5/02028 , A61B5/7275 , G09B23/30 , A61B34/10 , A61B5/743 , A61B5/7435 , A61B5/318 , A61B5/319 , A61B5/339 , A61B5/341 , G06V10/00 , G06V10/764 , A61B5/7267 , G16H50/50
Abstract: Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.
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公开(公告)号:US20230075266A1
公开(公告)日:2023-03-09
申请号:US17930155
申请日:2022-09-07
Inventor: David Krummen , Christopher Villongco
IPC: G06T7/00 , G16H50/20 , G16H30/40 , A61B5/055 , G16H50/50 , A61B5/00 , A61B6/03 , A61B6/00 , A61B5/25 , A61B5/291 , A61B5/318
Abstract: A method may include identifying a simulated three-dimensional representation corresponding to an internal anatomy of a subject based on a match between a computed two-dimensional image corresponding to the simulated three-dimensional representation and a two-dimensional image depicting the internal anatomy of the subject. Simulations of the electrical activities measured by a recording device with standard lead placement and nonstandard lead placement may be computed based on the simulated three-dimensional representation. A clinical electrogram and/or a clinical vectorgram for the subject may be corrected based on a difference between the simulations of electrical activities to account for deviations arising from patient-specific lead placement as well as variations in subject anatomy and pathophysiology.
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公开(公告)号:US20210321960A1
公开(公告)日:2021-10-21
申请号:US17110101
申请日:2020-12-02
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
IPC: A61B5/00 , G09B23/30 , A61B34/10 , A61B5/02 , A61B5/318 , A61B5/319 , A61B5/339 , A61B5/341 , A61B5/349
Abstract: A system is provided for generating a classifier for classifying electromagnetic data (e.g., ECG) derived from an electromagnetic source (e.g., heart). The system accesses a computational model of the electromagnetic source. The computational model models the electromagnetic output of the electromagnetic source over time based on a source configuration (e.g., rotor location) of the electromagnetic source. The system generates, for each different source configuration (e.g., different rotor locations), a modeled electromagnetic output (e.g., ECG) of the electromagnetic source for that source configuration. For each modeled electromagnetic output, the system derives the electromagnetic data for the modeled electromagnetic output and generates a label (e.g., rotor location) for the derived electromagnetic data from the source configuration for the modeled electromagnetic data. The system trains a classifier with the derived electromagnetic data and the labels as training data. The classifier can then be used to classify the electromagnetic output collected from patients.
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公开(公告)号:US10959680B2
公开(公告)日:2021-03-30
申请号:US17081556
申请日:2020-10-27
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
IPC: A61B5/00 , G16H50/50 , G16H50/20 , G06N20/00 , G09B23/30 , G06K9/62 , G06N3/08 , G06N5/04 , G06T19/20 , A61B34/10 , A61B5/02 , A61B5/107 , G06T3/40 , G06T17/20 , A61B5/316 , A61B5/318 , A61B5/319 , A61B5/339 , A61B5/341 , A61B5/349 , A61B5/364 , G06F30/20 , A61B6/03 , G09B23/28 , A61B5/25 , A61B5/361 , A61B5/363
Abstract: Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.
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公开(公告)号:US20190333642A1
公开(公告)日:2019-10-31
申请号:US16043011
申请日:2018-07-23
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
IPC: G16H50/50 , G06N99/00 , A61B5/0402 , G16H50/20 , G09B23/30
Abstract: Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.
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公开(公告)号:US20190328336A1
公开(公告)日:2019-10-31
申请号:US16043050
申请日:2018-07-23
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
IPC: A61B5/00 , A61B5/0402 , A61B5/0468 , A61B5/044
Abstract: Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.
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公开(公告)号:US20190328257A1
公开(公告)日:2019-10-31
申请号:US16162695
申请日:2018-10-17
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
Abstract: A system is provided for generating a classifier for classifying electromagnetic data (e.g., ECG) derived from an electromagnetic source (e.g., heart). The system accesses a computational model of the electromagnetic source. The computational model models the electromagnetic output of the electromagnetic source over time based on a source configuration (e.g., rotor location) of the electromagnetic source. The system generates, for each different source configuration (e.g., different rotor locations), a modeled electromagnetic output (e.g., ECG) of the electromagnetic source for that source configuration. For each modeled electromagnetic output, the system derives the electromagnetic data for the modeled electromagnetic output and generates a label (e.g., rotor location) for the derived electromagnetic data from the source configuration for the modeled electromagnetic data. The system trains a classifier with the derived electromagnetic data and the labels as training data. The classifier can then be used to classify the electromagnetic output collected from patients.
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公开(公告)号:US20230225655A1
公开(公告)日:2023-07-20
申请号:US18123922
申请日:2023-03-20
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco
CPC classification number: A61B5/243 , A61B5/352 , A61B5/339 , A61B5/743 , A61B5/7267 , A61B5/35 , A61B5/361
Abstract: A system is provided for displaying heart graphic information relating to sources and source locations of a heart disorder to assist in evaluation of the heart disorder. A heart graphic display system provides an intra-cardiogram similarity (“ICS”) graphic and a source location (“SL”) graphic. The ICS graphic includes a grid with the x-axis and y-axis representing patient cycles of a patient cardiogram with the intersections of the patient cycle identifiers indicating similarity between the patient cycles. The SL graphic provides a representation of a heart with source locations indicated. The source locations are identified based on similarity of a patient cycle to library cycles of a library cardiogram of a library of cardiograms.
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公开(公告)号:US20230005625A1
公开(公告)日:2023-01-05
申请号:US17784975
申请日:2021-10-22
Applicant: Christopher VILLONGCO , The Regents of the University of California , Vektor Medical, Inc.
Inventor: David Krummen , Kurt Hoffmayer , Christopher Villongco
Abstract: A non-invasive method for cardiac arrhythmia risk stratification may include identifying, based at least on an electrical recording of a patient, a cardiac depolarization simulation and a cardiac repolarization simulation corresponding to an electrical recording of a patient. One or more regions of increased spatial repolarization gradient in which a first area of a myocardium of the patient exhibits a first repolarization rate that differs from a second repolarization rate of a second area of the myocardium by an amount then divided by the spatial distance between the two regions, by a threshold value may be determined based on the cardiac depolarization simulation and the cardiac repolarization simulation. A risk of cardiac arrhythmia for the patient may be determined based a magnitude of the increased spatial repolarization gradient. Moreover, a treatment plan for the patient may be determined based on the magnitude and/or location of the increased spatial repolarization gradient.
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公开(公告)号:US20220192749A1
公开(公告)日:2022-06-23
申请号:US17590119
申请日:2022-02-01
Applicant: Vektor Medical, Inc.
Inventor: Christopher Villongco , Alexander Michael Monko
Abstract: Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.
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