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21.
公开(公告)号:US20200380673A1
公开(公告)日:2020-12-03
申请号:US16621800
申请日:2018-06-18
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Mannudeep Kalra , Juergen Hahn , Uwe Kruger , Wenxiang Cong , Hongming Shan
Abstract: Computed tomography (CT) screening, diagnosis, or another image analysis tasks are performed using one or more networks and/or algorithms to either integrate complementary tomographic image reconstructions and radiomics or map tomographic raw data directly to diagnostic findings in the machine learning framework. One or more reconstruction networks are trained to reconstruct tomographic images from a training set of CT projection data. One or more radiomics networks are trained to extract features from the tomographic images and associated training diagnostic data. The networks/algorithms are integrated into an end-to-end network and trained. A set of tomographic data, e.g., CT projection data, and other relevant information from an individual is input to the end-to-end network, and a potential diagnosis for the individual based on the features extracted by the end-to-end network is produced. The systems and methods can be applied to CT projection data, MRI data, nuclear imaging data, ultrasound signals, optical data, other types of tomographic data, or combinations thereof.
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22.
公开(公告)号:US20200273215A1
公开(公告)日:2020-08-27
申请号:US16647220
申请日:2018-09-26
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong
Abstract: A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening. An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.
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公开(公告)号:US10729397B2
公开(公告)日:2020-08-04
申请号:US15741026
申请日:2016-07-20
Inventor: Ge Wang , Wenxiang Cong , Zaifeng Shi , Shuo Pang
Abstract: Novel and advantageous systems and methods for performing X-ray imaging by extracting X-ray phase-shift and/or dark-field information through a detector that has built-in G2 functionality are provided. Grating translation can be replaced by an electrical operation in the detection procedure, thereby eliminating the need for the analyzer grating and the typical mechanical stepping process.
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公开(公告)号:US10539689B1
公开(公告)日:2020-01-21
申请号:US15545623
申请日:2016-01-25
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong , Zaifeng Shi
Abstract: Novel and advantageous methods and systems for performing computed tomography (CT) imaging are disclosed. Electrodes can be connected to appropriate surface sites of a detector element of a CT scanner to capture nearby electron-hole pairs generated by X-rays received on the detector element. This detection can be performed in current-integrating/energy-integrating mode.
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公开(公告)号:US20190261930A1
公开(公告)日:2019-08-29
申请号:US16347828
申请日:2017-11-07
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Qingsong Yang , Wenxiang Cong
Abstract: Methods and systems for stationary computed tomography are disclosed. The methods and systems include a gantry having alternating x-ray sources and x-ray detectors that are stationary during operation of the system. The gantry and pairs of x-ray sources and detectors substantially surrounds an object positioned inside the gantry during operation of the system. Dynamically adjustable collimators are positioned between the x-ray sources and the object. Each of the x-ray sources projects an x-ray beam through the collimators and through the object and the x-ray detectors receive the x-ray beam. The x-ray detectors include means for converting the x-ray beam to raw image data. One or more microprocessors control the x-ray sources and the process raw image data. A data storage device stores instructions, which upon execution by the microprocessor, control the x-ray sources and process the raw image data by converting the raw image data to a digital image.
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公开(公告)号:US20180353147A1
公开(公告)日:2018-12-13
申请号:US15579394
申请日:2016-06-06
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Qingsong Yang , Wenxiang Cong
CPC classification number: A61B6/5205 , A61B6/037 , A61B6/481 , A61B6/5258 , G06T11/003 , G06T11/005 , G21H5/02
Abstract: Systems and methods for determining an attenuation sinogram for a time-of-flight (TOF) positron emission tomography (PET) scan using only TOF PET data, and including use of the total amount of tracer provided to the subject of the TOF PET scan, are provided. The total amount of injected tracer can be used to determine the otherwise unknown constant shift present when an attenuation sinogram is estimated using the gradient of the attenuation sinogram. The attenuation sinogram can therefore be accurately and stably determined without any additional knowledge on the attenuation sinogram or map.
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公开(公告)号:US20180192981A1
公开(公告)日:2018-07-12
申请号:US15741047
申请日:2016-07-27
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Wenxiang Cong
IPC: A61B6/00
CPC classification number: A61B6/484 , A61B6/032 , A61B6/4007 , A61B6/4021 , A61B6/4028 , A61B6/4035 , A61B6/405 , A61B6/4064 , A61B6/4225 , A61B6/4233 , A61B6/4241 , A61B6/4291 , G21K2207/005 , H01J29/488 , H01J35/14
Abstract: Novel and advantageous systems and methods for performing X-ray imaging by using an X-ray source with source grating functionality incorporated therein are provided. An electron beam can be electromagnetically manipulated such that the X-ray source emits radiation in a pattern that is the same as if the radiation had already passed through a source grating.
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公开(公告)号:US20180068467A1
公开(公告)日:2018-03-08
申请号:US15558053
申请日:2016-03-21
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Mianyi Chen , Yan Xi , Wenxiang Cong
CPC classification number: G06T11/005 , A61B6/032 , A61B6/5205 , A61B6/582 , G06T11/006 , G06T2207/10116 , G06T2207/20 , G06T2211/412 , G06T2211/424
Abstract: Systems and methods for geometric calibration and image reconstruction in computed tomography (CT) scanning using iterative reconstruction algorithms are provided. An iterative reconstruction algorithm can be used to reconstruct an improved image, and then the improved image can be used to adjust inaccurate parameters by using a Locally Linear Embedding (LLE) method. Adjusted parameters can then be used to reconstruct new images, which can then be used to further adjust the parameters. The steps of this iterative process can be repeated until a quality threshold is met.
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公开(公告)号:US12154193B2
公开(公告)日:2024-11-26
申请号:US17859061
申请日:2022-07-07
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong , Qingsong Yang
Abstract: Systems and methods for reconstructing images for computed tomography are provided. Image reconstruction can be based on a realistic polychromatic physical model, and can include use of both an analytical algorithm and a single-variable optimization method. The optimization method can be used to solve the non-linear polychromatic X-ray integral model in the projection domain, resulting in an accurate decomposition for sinograms of two physical basis components.
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公开(公告)号:US12051134B2
公开(公告)日:2024-07-30
申请号:US17194946
申请日:2021-03-08
Applicant: University of Iowa Research Foundation , Shandong University , Shandong Public Health Clinical Center , Rensselaer Polytechnic Institute
Inventor: Wenxiang Cong , Ye Yangbo , Ge Wang , Shuwei Mao , Yingmei Wang
CPC classification number: G06T11/006 , A61B6/032 , G06T11/003 , G06T11/005 , G06T2211/408 , G06T2211/424
Abstract: The disclosed apparatus, systems and methods relate to a framelet-based iterative algorithm for polychromatic CT which can reconstruct two components using a single scan. The algorithm can have various steps including a scaled-gradient descent step of constant or variant step sizes; a non-negativity step; a soft thresholding step; and a color reconstruction step.
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