公开(公告)号：US20140203818A1

公开(公告)日：2014-07-24

申请号：US14092927

申请日：2013-11-28

Applicant: ACEA Biosciences, Inc.

Inventor： Xiaobo Wang ,  Wei Ouyang ,  Nan Li ,  Tianxing Wang ,  Xiaoyu Zhang ,  Xiao Xu ,  Yama A. Abassi

IPC: G01N27/02

CPC classification number: G01N27/02 ,  G01N33/4836

Abstract: Devices, systems and methods for monitoring excitable cells, such as cardiomyocytes, on microelectrode arrays that couple the electro-stimulation of excitable cells to induce or regulate cardiomyocyte beating and the simultaneous measurement of impedance and extracellular recording to assess changes in cardiomyocyte beating, viability, morphology or electrophysical properties in response to a plurality of treatments.

Abstract translation: 用于监测微电极阵列上的可兴奋细胞（例如心肌细胞）的装置，系统和方法，其耦合可刺激细胞的电刺激以诱导或调节心肌细胞搏动，以及同时测量阻抗和细胞外记录以评估心肌细胞跳动，活力， 响应于多种处理的形态或电物理性质。