公开(公告)号：US4730040A

公开(公告)日：1988-03-08

申请号：US7788

申请日：1987-01-28

申请人： Uwe Vagt ,  Rolf Fischer ,  Franz Merger ,  Hans-Martin Hutmacher

发明人： Uwe Vagt ,  Rolf Fischer ,  Franz Merger ,  Hans-Martin Hutmacher

IPC分类号： C07D223/04 ,  C07D201/08

CPC分类号： C07D201/08

摘要： .epsilon.-caprolactam is prepared by a process in which(a) a 5-formylvalerate is reacted with water in the presence of an acidic agent at from 30.degree. to 200.degree. C.,(b) the 5-formylvaleric acid thus obtained is reacted with excess ammonia and hydrogen in the presence of a hydrogenation catalyst and of a solvent which is inert under the reaction conditions, at from 50.degree. to 150.degree. C. under superatmospheric pressure, and(c) after the ammonia has been separated off, the resulting solution of 6-aminocaproic acid is heated to 150.degree.-370.degree. C. and the caprolactam formed is isolated.

摘要翻译： ε-己内酰胺通过以下方法制备：（a）在30℃至200℃下，在酸性试剂存在下，使5-甲酰基戊酸酯与水反应，（b）将所得的5-甲酰基戊酸反应 在氢化催化剂和在反应条件下为惰性的溶剂中，在超大气压下，在50-150℃下，过量的氨和氢，和（c）氨分离后， 将得到的6-氨基己酸溶液加热至150-370℃，形成己内酰胺。