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11.发明申请公开(公告)号：US20190000994A1
公开(公告)日：2019-01-03
申请号：US15996271
申请日：2018-06-01
申请人： New York University
摘要： The subject application is directed to a method for treating a mammal harboring a tumor comprising identifying a tumor associated antigen (TAA) expressed by the tumor and parenterally administering to the mammal a therapeutically effective amount of a Sindbis viral vector carrying a gene encoding the TAA to the mammal sufficient to elicit an immune response directed against the tumor, and thereby treating the tumor.
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12.发明授权公开(公告)号：US10010628B2
公开(公告)日：2018-07-03
申请号：US14478783
申请日：2014-09-05
申请人： New York University
CPC分类号： A61K48/0058 , A61K39/0011 , A61K2039/5256 , A61K2039/572 , C12N2770/36143
摘要： The subject application is directed to a method for treating a mammal harboring a tumor comprising identifying a tumor associated antigen (TAA) expressed by the tumor and parenterally administering to the mammal a therapeutically effective amount of a Sindbis viral vector carrying a gene encoding the TAA to the mammal sufficient to elicit an immune response directed against the tumor, and thereby treating the tumor.
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