公开(公告)号：US20200171053A1

公开(公告)日：2020-06-04

申请号：US16787796

申请日：2020-02-11

申请人： Intercept Pharmaceuticals, Inc. ,  Sumitomo Dainippon Pharma Co., Ltd.

发明人： Richard Gail Lancaster ,  Kay K. Olmstead ,  Masashi Kagihiro ,  Mitsuhiro Matono ,  Ikuko Taoka ,  Mark Pruzanski ,  David Shapiro ,  Roya Hooshmand-Rad ,  Richard Pencek ,  Cathi Sciacca ,  Lise Eliot ,  Jeffrey Edwards ,  Leigh A. MacConell ,  Tonya K. Marmon

IPC分类号： A61K31/575 ,  A61K45/06 ,  A61K9/20 ,  C07J9/00 ,  A61K9/14 ,  A61K9/16 ,  A61K47/50

摘要： The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

公开(公告)号：US20200054650A1

公开(公告)日：2020-02-20

申请号：US16597412

申请日：2019-10-09

申请人： Intercept Pharmaceuticals, Inc. ,  Sumitomo Dainippon Pharma Co., Ltd.

发明人： Richard Gail Lancaster ,  Kay K. Olmstead ,  Masashi Kagihiro ,  Mitsuhiro Matono ,  Ikuko Taoka ,  Mark Pruzanski ,  David Shapiro ,  Roya Hooshmand-Rad ,  Richard Pencek ,  Cathi Sciacca ,  Lise Eliot ,  Jeffrey Edwards ,  Leigh A. MacConell ,  Tonya K. Marmon

IPC分类号： A61K31/575 ,  A61K45/06 ,  A61K9/20 ,  C07J9/00 ,  A61K9/14 ,  A61K9/16 ,  A61K47/50

摘要： The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

公开(公告)号：US20190255071A1

公开(公告)日：2019-08-22

申请号：US16248512

申请日：2019-01-15

申请人： Intercept Pharmaceuticals, Inc. ,  Sumitomo Dainippon Pharma Co., Ltd.

发明人： Richard Gail Lancaster ,  Kay K. Olmstead ,  Masashi Kagihiro ,  Mitsuhiro Matono ,  Ikuko Taoka ,  Mark Pruzanski ,  David Shapiro ,  Roya Hooshmand-Rad ,  Richard Pencek ,  Cathi Sciacca ,  Lise Eliot ,  Jeffrey Edwards ,  Leigh A. MacConell ,  Tonya K. Marmon

IPC分类号： A61K31/575 ,  A61K45/06 ,  A61K9/20 ,  A61K47/50 ,  C07J9/00 ,  A61K9/16 ,  A61K9/14

摘要： The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.