公开(公告)号：US20190177389A1

公开(公告)日：2019-06-13

申请号：US16196829

申请日：2018-11-20

Applicant: Genentech, Inc.

Inventor： Justin SCHEER ,  Wenjun OUYANG ,  Richard VANDLEN ,  Philip E. HASS ,  Eric Gary STEFANICH ,  Ganesh A. KOLUMAM ,  Xiaoting WANG ,  Jed ROSS ,  Nicholas VAN BRUGGEN ,  Wyne P. LEE

IPC: C07K14/54 ,  A61K38/20 ,  A61K47/38 ,  C07K16/28

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.