公开(公告)号：US20140169524A1

公开(公告)日：2014-06-19

申请号：US13719815

申请日：2012-12-19

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Jonathan Immanuel Sperl ,  Dirk Wim Jos Beque

IPC: G06T5/00 ,  G01N23/04

CPC classification number: G06T5/001 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612

Abstract: A phase retrieval method for differential phase contrast imaging includes receiving data corresponding to a differential phase image generated from a measured signal. The measured signal corresponds to an X-ray signal detected by a detector after passing through a subject located with a grating arrangement between an X-ray source and the detector. The method further includes generating a phase image corresponding to the integration of the differential phase image. Generating the phase image includes performing an iterative total variation regularized integration in the Fourier domain.

Abstract translation: 用于差分相位对比成像的相位检索方法包括接收与从测量信号生成的差分相位图像相对应的数据。 所测量的信号对应于在通过位于X射线源和检测器之间的光栅布置的被摄物体之后由检测器检测的X射线信号。 该方法还包括产生与差分相位图像的积分相对应的相位图像。 生成相位图像包括在傅里叶域中执行迭代总变化正则化积分。

公开(公告)号：US20160334489A1

公开(公告)日：2016-11-17

申请号：US14711650

申请日：2015-05-13

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan

IPC: G01R33/563 ,  G01R33/56 ,  G01R33/561 ,  G01R33/385

CPC classification number: G01R33/56341 ,  G01R33/5608

Abstract: A magnetic resonance imaging method includes generating spatially resolved fiber orientation distributions (FODs) from magnetic resonance signals acquired from a patient tissue using a plurality of diffusion encodings, each acquired magnetic resonance signal corresponding to one of the diffusion encodings and being representative of a three-dimensional distribution of displacement of magnetic spins of gyromagnetic nuclei present in each imaging voxel. Generating the spatially resolved FODs includes performing generalized spherical deconvolution using the acquired magnetic resonance signals and a modeled tissue response matrix (TRM) to reconstruct the spatially resolved FODs. The method also includes using the spatially resolved FODs to generate a representation of fibrous tissue within the patient tissue.

Abstract translation: 磁共振成像方法包括使用多个扩散编码从从患者组织获取的磁共振信号产生空间分辨纤维取向分布（FOD），每个获得的磁共振信号对应于一个扩散编码，并且代表三维 每个成像体素中存在的回旋磁核的磁自旋的位移的尺寸分布。 生成空间分辨的FOD包括使用获取的磁共振信号和建模的组织响应矩阵（TRM）来执行广义的球形去卷积以重构空间分辨的FOD。 该方法还包括使用空间分辨的FOD来产生患者组织内的纤维组织的表示。

公开(公告)号：US09330456B2

公开(公告)日：2016-05-03

申请号：US14264689

申请日：2014-04-29

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Kinan Mahdi

IPC: G06K9/00 ,  G06T7/00 ,  A61B6/00 ,  G01N23/04 ,  G06K9/52

CPC classification number: G06T7/0012 ,  A61B6/484 ,  A61B6/5205 ,  A61B6/5211 ,  G01N23/04 ,  G06K9/0014 ,  G06K9/52 ,  G06K9/522 ,  G06T5/002 ,  G06T5/50 ,  G06T2207/10116 ,  G06T2207/20056 ,  G06T2207/30004

Abstract: A method of regularization of x-ray phase contrast imaging (XPCi) system measurement data includes obtaining air scan data of the XPCi system prior to the presence of an object undergoing imaging, performing Fourier analysis of the air scan data, computing air coefficients from the result of the performing step, obtaining object scan data of an object undergoing imaging on the XPCi system, regularizing the object scan data, and calculating at least one of absorption image data, differential phase image data, and dark field image data by using object coefficients. A system configured to implement the method and a non-transitory computer-readable medium are disclosed.

Abstract translation: x射线相位成像（XPCi）系统测量数据的正则化方法包括在存在正在进行成像的对象之前获得XPCi系统的空气扫描数据，执行空中扫描数据的傅里叶分析，计算来自 执行步骤的结果，获得在XPCi系统上进行成像的对象的对象扫描数据，使对象扫描数据正规化，以及通过使用对象系数来计算吸收图像数据，差分相位图像数据和暗场图像数据中的至少一个 。 公开了一种被配置为实现该方法的系统和一种非暂时的计算机可读介质。

公开(公告)号：US08989347B2

公开(公告)日：2015-03-24

申请号：US13719815

申请日：2012-12-19

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Dirk Wim Jos Beque

IPC: G06T7/00 ,  G01N23/04 ,  G06T5/00

CPC classification number: G06T5/001 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612

Abstract: A phase retrieval method for differential phase contrast imaging includes receiving data corresponding to a differential phase image generated from a measured signal. The measured signal corresponds to an X-ray signal detected by a detector after passing through a subject located with a grating arrangement between an X-ray source and the detector. The method further includes generating a phase image corresponding to the integration of the differential phase image. Generating the phase image includes performing an iterative total variation regularized integration in the Fourier domain.

Abstract translation: 用于差分相位对比成像的相位检索方法包括接收与从测量信号生成的差分相位图像相对应的数据。 所测量的信号对应于在通过位于X射线源和检测器之间的光栅布置的被摄物体之后由检测器检测的X射线信号。 该方法还包括产生与差分相位图像的积分相对应的相位图像。 生成相位图像包括在傅里叶域中执行迭代总变化正则化积分。

公开(公告)号：US08908951B2

公开(公告)日：2014-12-09

申请号：US13728871

申请日：2012-12-27

Applicant: General Electric Company

Inventor： Marion Irene Menzel ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Luca Marinelli ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G01R33/56341

Abstract: A magnetic resonance (MR) imaging method includes acquiring MR signals having phase and magnitude at q-space locations using a diffusion sensitizing pulse sequence performed on a tissue of interest, wherein the acquired signals each include a set of complex Fourier encodings representing a three-dimensional displacement distribution of the spins in a q-space location. The signals each include information relating to coherent motion and incoherent motion in the q-space location. The method also includes determining a contribution by coherent motion to the phase of the acquired MR signals; removing the phase contribution attributable to coherent motion from the acquired MR signals to produce a complex data set for each q-space location and an image of velocity components for each q-space location; and producing a three-dimensional velocity image from the image of the velocity components.

Abstract translation: 磁共振（MR）成像方法包括使用在感兴趣的组织上执行的扩散增感脉冲序列获取在q空间位置具有相位和幅度的MR信号，其中所获取的信号各自包括一组代表三维空间的复数傅里叶编码， 在q空间位置的自旋的三维位移分布。 每个信号包括与q空间位置中的相干运动和非相干运动有关的信息。 该方法还包括通过相干运动确定所获取的MR信号的相位的贡献; 从所获取的MR信号去除归因于相干运动的相位贡献，以产生用于每个q空间位置的复数据集合和用于每个q空间位置的速度分量的图像; 并根据速度分量的图像产生三维速度图像。

公开(公告)号：US20140185757A1

公开(公告)日：2014-07-03

申请号：US13731447

申请日：2012-12-31

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Jonathan Immanuel Sperl ,  Dirk Beque

IPC: A61B6/00 ,  G06T7/00

CPC classification number: A61B6/484 ,  G06T5/001 ,  G06T5/10 ,  G06T7/0012 ,  G06T11/003 ,  G06T2207/10116

Abstract: An image reconstruction method for differential phase contrast imaging includes receiving data corresponding to a signal produced by an X-ray detector and corresponding to X-rays that passed through a subject and a grating system to reach the X-ray detector. The method also includes performing a fringe analysis on the received data. The fringe analysis includes a non-integer fringe fraction correction utilizing one or more adapted basis functions in the Fourier domain to determine one or more Fourier coefficients. A differential phase image of the subject is generated by utilizing the one or more Fourier coefficients.

Abstract translation: 用于差分相位对比成像的图像重建方法包括：接收对应于由X射线检测器产生的信号的数据，并对应于穿过被摄体的X射线和光栅系统到达X射线检测器。 该方法还包括对所接收的数据执行边缘分析。 边缘分析包括利用傅立叶域中的一个或多个适应的基函数来确定一个或多个傅立叶系数的非整数边缘分数校正。 通过利用一个或多个傅立叶系数来产生对象的差分相位图像。