公开(公告)号：US3687982A

公开(公告)日：1972-08-29

申请号：US3687982D

申请日：1971-03-09

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： YOUNG VERNON V

IPC: C07D313/00 ,  C07D9/00

CPC classification number: C07D313/00

Abstract: A mixture of the diastereoisomers of zearalanol is formed when zearalenone is catalytically reduced in the presence of hydrogen. Separation of the diastereoisomers can be effected by converting them to a mixture of their 6''-acetate esters, separating the 6''acetate esters by fractional crystallization from a monohydric alkanol of one to five carbon atoms, e.g., from methanol, and deesterifying the separated esters to yield separated zearalanol diastereoisomers.

Abstract translation: 在玉米赤兰烯酮在氢存在下催化还原时，形成了zearalanol的非对映异构体的混合物。 非对映异构体的分离可以通过将它们转化成它们的6'-乙酸酯的混合物来实现，通过从1至5个碳原子的一元链烷醇（例如甲醇）分离6'-乙酸酯来分离， 酯化分离的酯以产生分离的玉米赤霉烯醇非对映异构体。

公开(公告)号：US3580929A

公开(公告)日：1971-05-25

申请号：US3580929D

申请日：1968-04-16

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： HIDY PHIL H ,  YOUNG VERNON V

IPC: C07D313/00 ,  C12P17/08 ,  C07D9/00

CPC classification number: C07D313/00 ,  C12P17/08 ,  Y10S435/803 ,  Y10S435/911

Abstract: A PROCESS FOR THE RECOVERY OF A FERMENTATION PRODUCT FROM A POROUS SUBSTRATE SUCH AS RECOVERY OF THE ANABOLIC AND ESTROGENIC SUBSTANCE KNOWN AT F.E.S., IDENTIFIED IN U.S. PAT. NO. 3,196,019, PRODUCED BY CULTIVATION OF THE MICROOGANISM GIBBERELLA ZEAE (GORDON) ON A POROUS SUBSTRATE, ESPECIALLY FROM A SYNTHETIC FERMENTATION MEDIUM WHICH INCLUDES EXFOLIATED VERMICULITE AS A SUPPORT FOR THE MICROORGANISM AND A NUTRIENT PRODUCTION MEDIUM INCLUDING SUGAR AS THE CARBOHYDRATE SOURCE AND ADDED MINERALS DESIRED FOR PROPER GROWTH OF THE MICROORGANISM. IN THIS RECOVERY PROCESS THE POROUS SUBSTRATE OR FERMENTATION CAKE IS CRUSHED AND SLURRIED WITH AN AQUEOUS ALKALINE SOLUTION TO DISSOLVE THE NORMALLY WATER-INSOLUBLE F.E.S. THE SOLUTION IS THEN FILTERED AND ACIDIFIED TO PRECIPITATE THE F.E.S. WHICH IS RECOVERED. THE SOLUTION IS HEATED PRIOR TO OR DURING ACIDIFICATION TO INSURE THE PRODUCTION OF EASILY FILTERABLE F.E.S. CRYSTALS.

公开(公告)号：US3267142A

公开(公告)日：1966-08-16

申请号：US41233464

申请日：1964-11-19

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： YOUNG VERNON V

IPC: B01J23/68

CPC classification number: B01J23/685

公开(公告)号：US2864863A

公开(公告)日：1958-12-16

申请号：US66566357

申请日：1957-06-14

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： YOUNG VERNON V

IPC: C07C209/48

CPC classification number: C07C209/48

公开(公告)号：US2587574A

公开(公告)日：1952-02-26

申请号：US14558850

申请日：1950-02-21

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： YOUNG VERNON V

IPC: C07D499/00 ,  C07D499/24

CPC classification number: C07D499/00