Albumin-binding PSMA inhibitors
    11.
    发明授权

    公开(公告)号:US11147889B2

    公开(公告)日:2021-10-19

    申请号:US16349756

    申请日:2017-11-24

    IPC分类号: A61K49/10 C07D225/08

    摘要: Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 are each independently a covalent bond or a divalent linking group, R is a detectable label or therapeutic drug and B is an albumin binding moiety. Also provided are compositions including a compound of Formula (I) together with a pharmaceutically acceptable carrier, and methods for imaging prostate cancer cells using a compound of Formula (I).