DOWN SYNDROME MODEL RAT AND METHOD FOR PRODUCING SAME

    公开(公告)号:US20200029539A1

    公开(公告)日:2020-01-30

    申请号:US16337381

    申请日:2017-09-28

    IPC分类号: A01K67/027 C12N15/02

    摘要: In this application, the provided are: a Down syndrome rat model characterized in that a rat gene homologous to at least one gene present on a human chromosome 21 or fragment thereof is a trisomy and is transmittable to progeny; or a Down syndrome rat model characterized in that it comprises a human chromosome 21 or fragment thereof, or an exogenous rat chromosome or fragment thereof on which a rat gene homologous to the human chromosome 21 or fragment thereof is present, wherein at least one gene on the human chromosome 21 or fragment thereof or on the exogenous rat chromosome or fragment thereof is added to endogenous rat genes homologous to the at least gene so as to become a trisomy and to be transmittable to progeny: and a method for producing the Down syndrome rat model.

    Agent for preventing adverse side effects of carcinostatic agent
    17.
    发明授权
    Agent for preventing adverse side effects of carcinostatic agent 有权
    防止制癌剂副作用的药剂

    公开(公告)号:US08974796B2

    公开(公告)日:2015-03-10

    申请号:US13377887

    申请日:2010-02-22

    IPC分类号: A61K36/03 A61K31/737

    CPC分类号: A61K31/737 A61K36/03

    摘要: The present invention provides a side effect inhibitor of drug therapy for colorectal cancer using 5-fluorouracil, comprising fucoidan or a fucoidan-containing material; a method for inhibiting side effects of drug therapy for colorectal cancer using 5-fluorouracil, which comprises administering fucoidan or a fucoidan-containing material to a colorectal cancer patient; and use of fucoidan or a fucoidan-containing material for the production of a side effect inhibitor of drug therapy for colorectal cancer using 5-fluorouracil.

    摘要翻译: 本发明提供使用5-氟尿嘧啶,包含岩藻依聚糖或含岩藻依聚糖的材料的结肠直肠癌药物治疗的副作用抑制剂; 一种使用5-氟尿嘧啶抑制药物治疗结直肠癌副作用的方法,其包括对结肠直肠癌患者施用岩藻依聚糖或含岩藻依聚糖的材料; 以及使用含有岩藻依聚糖的岩藻多糖或含有岩藻依聚糖的材料用于使用5-氟尿嘧啶生产结肠直肠癌药物治疗副作用抑制剂。

    Diagnosis processing device, diagnosis processing system, diagnosis processing method, diagnosis processing program and computer-readable recording medium, and classification processing device
    20.
    发明授权
    Diagnosis processing device, diagnosis processing system, diagnosis processing method, diagnosis processing program and computer-readable recording medium, and classification processing device 有权
    诊断处理装置,诊断处理系统,诊断处理方法,诊断处理程序和计算机可读记录介质以及分类处理装置

    公开(公告)号:US08798345B2

    公开(公告)日:2014-08-05

    申请号:US13496391

    申请日:2010-08-16

    IPC分类号: G06K9/00 G06K9/62

    摘要: A diagnosis processing device is provided in which diagnosis is realizable by a simple arrangement. A diagnosis processing device (1) of the present invention includes: a learning pattern creating section (10a) for creating a learning pattern by sampling data from a learning image in which abnormality information indicating a substantive feature of abnormality of a target is pre-known; a learning processing section (12) for causing a neural network (17) to learn, by using learning patterns; a diagnostic pattern creating section (10b) for creating a diagnostic pattern by sampling data from a diagnostic image in which abnormality information is unknown; a determination processing section (18) for determining a substantive feature of the abnormality of the target indicated in the abnormality information in the diagnostic image, based on an output value outputted, in response to an input of the diagnostic pattern, from a learned neural network (17) which is a neural network subjected to learning.

    摘要翻译: 提供一种诊断处理装置,其中可以通过简单的布置来实现诊断。 本发明的诊断处理装置(1)包括:学习图案生成部(10a),用于通过从表示目标的异常的实质特征的异常信息是已知的学习图像进行采样来创建学习模式 ; 学习处理部(12),用于使神经网络(17)通过使用学习模式学习; 诊断图案生成部(10b),用于通过从异常信息未知的诊断图像中取样数据来生成诊断图案; 确定处理部(18),用于基于从所述诊断图案的输入而输出的输出值,从所学习的神经网络中确定所述诊断图像中的异常信息中指示的所述目标的异常的实质特征 (17),它是受到学习的神经网络。