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公开(公告)号:US10851384B2
公开(公告)日:2020-12-01
申请号:US16149456
申请日:2018-10-02
摘要: This disclosure provides tobacco plants having a mutation in PR50 and transgenic tobacco plants containing a PR50 RNAi, and methods of making and using such plants.
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公开(公告)号:US10851367B2
公开(公告)日:2020-12-01
申请号:US15347339
申请日:2016-11-09
摘要: The present application provides compounds, compositions, uses thereof for the treatment of diseases, conditions and/or disorders, and uses thereof as asialoglycoprotein receptor (ASGPR) targeting agents.
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公开(公告)号:US10829828B2
公开(公告)日:2020-11-10
申请号:US15228465
申请日:2016-08-04
发明人: Daniel Ader , Matthew W. Dimmic , Zhaolong Li , Robert Douglas Sammons , Ronak Hasmukh Shah , Nengbing Tao , Dafu Wang
摘要: The present invention provides novel compositions for use to enhance weed control. Specifically, the present invention provides for methods and compositions that modulate Acetyl-CoA carboxylase in weed species. The present invention also provides for combinations of compositions and methods that enhance weed control.
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公开(公告)号:US10813318B2
公开(公告)日:2020-10-27
申请号:US15914033
申请日:2018-03-07
IPC分类号: A01H5/12 , C07K14/415 , A01H1/02 , A24B15/20 , C12N15/82 , A01H1/06 , C12Q1/6895 , G01N33/00
摘要: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.
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公开(公告)号:US10793869B2
公开(公告)日:2020-10-06
申请号:US15637859
申请日:2017-06-29
发明人: Edwards M. Allen , Larry A Gilbertson , Sara E. Heisel , Shihshieh Huang , Elysia K. Krieger , Thomas M. Malvar
IPC分类号: C12N15/82 , C12N15/113
摘要: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
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公开(公告)号:US10669317B2
公开(公告)日:2020-06-02
申请号:US15849012
申请日:2017-12-20
发明人: James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC分类号: C07K14/325 , C12N15/82 , A01N63/10 , C12N15/62
摘要: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号:US10655136B2
公开(公告)日:2020-05-19
申请号:US15579120
申请日:2016-06-02
摘要: The present disclosure provides compositions and methods for introducing nucleic acids into plants. More specifically, disclosed herein are methods and compositions for introducing a nucleic acid, such as a double-stranded RNA, for silencing a target gene in a plant. Also disclosed herein are plants exhibiting modification of a target gene, obtained through the use of such methods and compositions.
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公开(公告)号:US10647989B2
公开(公告)日:2020-05-12
申请号:US15727523
申请日:2017-10-06
摘要: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radical absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
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公开(公告)号:US10570414B2
公开(公告)日:2020-02-25
申请号:US15348839
申请日:2016-11-10
发明人: Edwards Allen , William P. Donovan , Gregory R. Heck , James K. Roberts , Virginia Ursin , Yuanji Zhang
IPC分类号: C12N15/82 , A01N63/02 , C12N15/113
摘要: This invention provides plants having resistance to invertebrate pests. More specifically, this invention discloses a non-natural transgenic plant cell expressing at least one invertebrate miRNA in planta for suppression of a target gene of an invertebrate pest or of a symbiont associated with the invertebrate pest. Also provided are recombinant DNA constructs for expression of at least one invertebrate miRNA in planta, a non-natural transgenic plant containing the non-natural transgenic plant cell of this invention, a non-natural transgenic plant grown from the non-natural transgenic plant cell of this invention, and non-natural transgenic seed produced by the non-natural transgenic plants, as well as commodity products produced from a non-natural transgenic plant cell, plant, or seed of this invention. This invention further provides a method of suppressing at least one target gene of an invertebrate pest of a plant or of a symbiont associated with the invertebrate, including providing a plant including the non-natural transgenic plant cell of this invention, wherein the invertebrate is the invertebrate pest, the recombinant DNA is transcribed in the non-natural transgenic plant cell to the recombinant miRNA precursor, and when the invertebrate pest ingests the recombinant miRNA precursor, the at least one target gene is suppressed.
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