公开(公告)号：US20220383562A1

公开(公告)日：2022-12-01

申请号：US17753452

申请日：2021-01-06

Applicant: TOMOCUBE, INC. ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： YongKeun PARK ,  Donghun RYU ,  HyunSeok MIN ,  Dongmin RYU

IPC: G06T11/00 ,  G06V10/82

Abstract: Proposed are a method and device for regularizing rapid three-dimensional tomographic imaging using a machine-learning algorithm. A method for regularizing three-dimensional tomographic imaging using a machine-learning algorithm according to an embodiment comprises the steps of: measuring a three-dimensional tomogram of a cell to acquire a raw tomogram of the cell; acquiring a regularized tomogram by using a regularization algorithm; and learning the relationship between the raw tomogram and the regularized tomogram through machine-learning.

公开(公告)号：US20230410256A1

公开(公告)日：2023-12-21

申请号：US17818987

申请日：2022-08-11

Applicant: Tomocube, Inc.

Inventor： Hyunseok MIN ,  Dongmin RYU ,  Woonsoo LEE ,  Hansol YOON

IPC: G06T3/40 ,  G02B21/36

CPC classification number: G06T3/4053 ,  G06T3/4046 ,  G06T2200/04 ,  G06T3/4038 ,  G02B21/367 ,  G06T3/4023

Abstract: The present disclosure provides a system and method for improving image resolution of a three-dimensional (3-D) refractive index microscope based on an artificial intelligence (AI) technology. The present disclosure provides a technology for converting a low-resolution 3-D refractive index microscope image into a high-resolution 3-D refractive index image without physical machine conversion and re-photographing based on AI. That is, the present disclosure applies an AI technology, such as deep learning, in order to train an AI model with a physical correlation between a low-resolution 3-D refractive index microscope image and a high-resolution 3-D refractive index image of various samples, such as a cell and a tissue, and convert a low resolution image into a high resolution image without a change in a physical microscope based on the training. Furthermore, for the training of the AI model, the present disclosure uses physical characteristics of a refractive index image.